53020-4

Complement C1q Ab [Presence] in Serum

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Part Descriptions

LP16352-4 Complement C1q
A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY. Source: National Library of Medicine, MeSH 2006

LP16352-4 Complement C1q
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement (C1) is composed of 3 subunits: C1q, C1r, and C1s. Complement C1q initiates the complement pathway by binding to immunoglobulins. Absent or decreased levels of Complement C1q are seen in patients with acquired angioedema, systemic lupus erythematosus (SLE), polymyositis, and other immune complex diseases. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency. Source: Regenstrief Institute

Fully-Specified Name

Component: Complement C1q Ab
Property: PrThr
Time: Pt
System: Ser
Scale: Ord
Method

Additional Names

Long Common Name: Complement C1q Ab [Presence] in Serum
Short Name: C1q Ab Ser Ql
Display Name: Complement C1q Ab Ql (S)
Consumer Name Alpha Get Info: Complement C1q antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: HEM/BC
Type: Laboratory
First Released: Version 2.24
Last Updated: Version 2.56
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Komplement C1q Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:
es-ES	Spanish (Spain)	Complemento C1q Anticuerpos:PrThr:Punto temporal:Suero:Ord:
es-MX	Spanish (Mexico)	Complemento C1q Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:
et-EE	Estonian (Estonia)	Komplemendi komponent C1q antikehad:PrThr:Pt:S:Ord: Synonyms: Järgarvuline Juhuslik Seerum
fr-CA	French (Canada)	Complément C1q, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FR	French (France)	Complément C1q anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
fr-BE	French (Belgium)	Complément C1q Ac:PrThr:Temps ponctuel:Sérum:Ordinal: Synonyms: Anticorps
it-IT	Italian (Italy)	Complemento C1q Ab:PrThr:Pt:Siero:Ord: Synonyms: anticorpo Ematologia (coagulazione) conta differenziale Presenza o Soglia Punto nel tempo (episodio) Siero
nl-NL	Dutch (Netherlands)	complement C1q As:aanwezigheid:moment:serum:ordinaal: Synonyms: antistof; antilichaam
pt-BR	Portuguese (Brazil)	Complemento C1q Ac:ACnc:Pt:Soro:Ord: Synonyms: Complement c1q binding; Complmt; Comp; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS
ru-RU	Russian (Russian Federation)	Комплемент C1q Ат:PrThr:ТчкВрм:Сыв:Пор: Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Kompleman C1q Ab:MevcEşik:Zmlı:Ser:Srl: Synonyms: Ak Mevcut
zh-CN	Chinese (China)	补体 C1q 抗体:存在情况或阈值:时间点:血清:序数型: Synonyms: Ab;自身抗体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间血液学/细胞计数;血液学与细胞计数补体 C1q Ab

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.