53020-4
Complement C1q Ab [Presence] in Serum
Active
Part Descriptions
LP16352-4 Complement C1q
A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY.
Source: National Library of Medicine, MeSH 2006
LP16352-4 Complement C1q
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement (C1) is composed of 3 subunits: C1q, C1r, and C1s. Complement C1q initiates the complement pathway by binding to immunoglobulins. Absent or decreased levels of Complement C1q are seen in patients with acquired angioedema, systemic lupus erythematosus (SLE), polymyositis, and other immune complex diseases. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Complement C1q Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
Additional Names
- Short Name
- C1q Ab Ser Ql
- Display Name
- Complement C1q Ab Ql (S)
- Consumer Name Alpha Get Info
- Complement C1q antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.24
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Komplement C1q Ak: |
| es-ES | Spanish (Spain) | Complemento C1q Anticuerpos: |
| es-MX | Spanish (Mexico) | Complemento C1q Ab: |
| et-EE | Estonian (Estonia) | Komplemendi komponent C1q antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | Complément C1q , Ac: |
| fr-FR | French (France) | Complément C1q anticorps: |
| fr-BE | French (Belgium) | Complément C1q Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Complemento C1q Ab: Synonyms: anticorpo Ematologia (coagulazione) conta differenziale Presenza o Soglia Punto nel tempo (episodio) Siero |
| nl-NL | Dutch (Netherlands) | complement C1q As: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Complemento C1q Ac: Synonyms: Complement c1q binding; |
| ru-RU | Russian (Russian Federation) | Комплемент C1q Ат: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Kompleman C1q Ab: Synonyms: Ak Mevcut |
| zh-CN | Chinese (China) | 补体 C1q 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=53020-4
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright