53151-7

Valine/Phenylalanine [Molar ratio] in DBS

Active

Term Description

Valine/Phenylalanine is a primary marker for Maple syrup urine disease and Valinemia.
Source: Regenstrief LOINC

Part Descriptions

LP15946-4   Valine
Valine, one of the 20 proteinogenic amino acids, is nutritionally essential. It is named after the plant valerian. Foods that are good sources of valine include cottage cheese, fish, poultry, peanuts, sesame seeds, and lentils. In sickle cell disease, the replacement of an A by T in the beta chain gene of hemoglobin changes the codon GAG (for glutamic acid) to GTG (which encodes valine). Thus valine, a hydrophic amnio acid, replaces glutamic acid, a hydrophilic amino acid, causing hemoglobin to not fold correctly. It is also a precursor in the penicillin biosynthetic pathway. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Valine (Wikipedia)

LP15946-4   Valine
A branched-chain essential amino acid that stimulates activity and promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway. Source: National Library of Medicine, MeSH 2006

LP15946-4   Valine
Valine is a branched-chain amino acid that stimulates activity and promotes muscle growth and tissue repair. It is elevated in branched-chain ketoaciduria (maple syrup urine disease), along with leucine, isoleucine, and alloisoleucine. Source: Regenstrief Institute

LP70160-4   Phenylalanine
Phenylalanine is an essential alpha-amino acid. It exists in two forms, a D and an L form, which are enantiomers (mirror-image molecules) of each other. It has a benzyl side chain and its name comes from its chemical structures that consists of a phenyl group substituted for one of the hydrogens in the side chain of alanine. Because of its phenyl group, phenylalanine is an aromatic compound that at room temperature exists as a white, powdery solid. L -phenylalanine (LPA) is an electrically-neutral amino acid and its enantiomer, D -phenylalanine (DPA), can be synthesized artificially. L -phenylalanine can also be converted into L -tyrosine, another one of the twenty protein-forming amino acids. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Phenylalanine (Wikipedia)

Fully-Specified Name

Component

Valine/Phenylalanine

Property

SRto

Time

Pt

System

Bld.dot

Scale

Qn

Method

Additional Names

Short Name

Valine/Phe DBS-sRto

Display Name

Valine/Phenylalanine (DBS) [Molar ratio]

Consumer Name Alpha Get Info

Valine/Phenylalanine, Dried blood spot

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.24

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

18115

Member of these Panels

Language Variants Get Info

Related Names

• Blood
• Chemistry
• DBS
• Dried blood spot
• Filter paper
• FP
• Phe
• PKU
• Point in time
• PPA
• QNT
• Quan
• Quant
• Quantitative
• Random
• Scrto
• Substance concentration ratio
• Substance ratio
• Val
• WB
• Whole blood

Example Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.

CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53151-7

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.