Version 2.77

Term Description

Antineuronal Nuclear Antibody (ANNA) Type 2 Cerebrospinal Fluid (CSF) Titer. This antibody recognizes a set of protein antigens of 55 and 80 kD found in neuronal cell nuclei. Patients usually present with signs of midbrain, brain stem, cerebellar and/or spinal cord dysfunction. Ocular opsoclonus-myoclonus may be a symptom. Para neoplastic opsoclonus, which is characterized by involuntary rapid movement of the eyes in both vertical and horizontal planes, is most often associated with breast cancer and SCLC (small lung cell carcinoma). The autoantibody has also been detected in patients with bladder and cervical cancer. Paraneoplastic syndromes are autoantibody-mediated neurologic disorders associated with underlying tumors. These syndromes arise when systemic tumors express antigens normally found only in neural tissues. Information from http://www.clinlabnavigator.com accessed 2008 14 02.
Source: Regenstrief LOINC

Part Descriptions

LP14164-5   Neuronal nuclear type 2
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable. Source: ARUP Laboratories, ANNA

LP39195-0   Neuronal nuclear type 2 Ab
Neuronal nuclear antibody is a neuronal paraneoplastic antibody that has been associated with cerebellar degeneration in breast, small cell lung carcinoma and gynecological cancers. Source: University of Birmingham, Neuronal antibodies

Fully-Specified Name

Component
Neuronal nuclear type 2 Ab
Property
Titr
Time
Pt
System
CSF
Scale
SemiQn
Method

Additional Names

Short Name
Hu2 Ab Titr CSF
Display Name
Neuronal nuclear type 2 Ab (CSF) [Titer]
Consumer Name Alpha Get Info
Neuronal nuclear type 2 antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.75
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG8744-7 Neuronal nuclear type 2 Ab|Titr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Anticuerpos Antineuronal nuclear tipo 2 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Nuclear neuronal tipo 2 Ab:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-CA French (Canada) Neuronal nucléaire de type 2 , Ac:Titre:Temps ponctuel:LCR:SemiQn:
fr-FR French (France) Hu2 anticorps:Titre:Ponctuel:Liquide céphalorachidien:Numérique:
it-IT Italian (Italy) Nucleare neuronale tipo 2 Ab:Titr:Pt:LCS:SemiQn:
Synonyms: anticorpo Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NL Dutch (Netherlands) neuronaal nucleair type 2 As:titer:moment:liquor cerebrospinalis:semikwantitatief:
Synonyms: antistof; antilichaam soort
pl-PL Polish (Poland) Typ 2 neuronalny jądrowy Ab:miano:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:
Synonyms: Przeciwciała do antygenów jądrowych komórek nerwowych typu 2 Przeciwciała onkoneuronalne
pt-BR Portuguese (Brazil) Neuronal nuclear tipo 2 Ac:Título:Pt:LCR:Qn:
Synonyms: Nuc; Hu2; Ri; ANNA 2; Neuronal nuclear type II; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
zh-CN Chinese (China) 神经元细胞核 2 型 抗体:滴定度:时间点:脑脊液:半定量型:
Synonyms: Ⅱ Ab;自身抗体 ANNA 2 Ab ANNA 2 抗体 ANNA 2;ANNA-2;Hu2;Ri;神经元核 2 型;神经元细胞核 2 型（Neuronal nuclear type 2，ANNA 2） ANNA-2 Ab ANNA-2 抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Hu2 Ab Hu2 抗体 II Ri Ab Ri 抗体 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 核;胞核 神经元性;神经元的 神经元核 神经元核 2 型 Ab 神经元核 2 型抗体 神经元细胞核 2 型 Ab 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
titer REGENSTRIEF
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53712-6