54069-0
Hemoglobin Barts/Hemoglobin.total in DBS
Active
Part Description
LP16418-3 Hemoglobin Barts
Hemoglobin Barts is a relatively common hemoglobin variant consisting of four gamma chains. Hemoglobin Barts is an extremely high affinity hemoglobin that is not effective at delivering oxygen to tissues. Hemoglobin Barts is only seen during the newborn period and usually indicates that one or more of the baby's alpha-globin genes are deleted, resulting in alpha-thalassemia. Alpha thalassemia is caused by deletions of the alpha globin genes on chromosome 16. Normal patients have four copies of the alpha-globin gene, 2 on each chromosome. A silent carrier will have one deleted alpha gene and usually result in a benign condition. Alpha thalassmia trait occurs when there are two deleted alpha genes, resulting in mild or no anemia with microcytosis and hypochromia. Hemoglobin H disease results from the deletion of three alpha genes with resultant moderately severe alpha thalassemia. Most patients are anemic and display some degree of splenomegaly. Fetal hydrops syndrome occurs when all four alpha genes are deleted. Fetal hydrops is not compatible with life and death occurs in utero or during early infancy.Carrier states for alpha thalassemia are very common in the African, Meditteranean and Asian populations. In general, only the loss of one or two genes is seen in African Americans. Asian and Meditteranean populations may have all types of alpha thalassemia. Information from The Georgia Comphensive Sickle Cell Center at Grady Health System, Emory University School of Medicine Department of Pediatrics, Atlanta, GA at www.scinfo.org, accessed 2007 11 02, and The Utah Department of Health at www.health.utah.gov, accessed 2007 11 02.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Hemoglobin Barts/Hemoglobin.total
- Property
- MFr
- Time
- Pt
- System
- Bld.dot
- Scale
- Qn
- Method
Additional Names
- Short Name
- Hgb Barts MFr DBS
- Display Name
- Hemoglobin Barts (DBS) [Mass fraction]
- Consumer Name Alpha Get Info
- Hemoglobin barts/Total Hgb, Dried blood spot
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.26
- Last Updated
- Version 2.61
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
104191-2 | Guanidinoacetate methyltransferase (GAMT) deficiency newborn screening panel |
54081-5 | Hemoglobinopathies newborn screening panel |
54089-8 | Newborn screening panel American Health Information Community (AHIC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Hemoglobina Barts/Hemoglobina.total: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Barts de hemoglobina / hemoglobina total: |
fr-CA | French (Canada) | Hémoglobine Bart/Hémoglobine.totale: |
fr-FR | French (France) | Hémoglobine Barts/hémoglobine totale: |
fr-BE | French (Belgium) | Hémoglobine Bart/Hémoglobine.totale: Synonyms: Hb Hb Bart Hb.totale |
it-IT | Italian (Italy) | Emoglobina Bart/Emoglobina.totale: Synonyms: Ematologia (coagulazione) conta differenziale Emoglobina di Bart Frazione di massa Punto nel tempo (episodio) Sangue Spot sangue secco |
nl-NL | Dutch (Netherlands) | hemoglobine Barts/hemoglobine.totaal: |
pl-PL | Polish (Poland) | Hemoglobina Barts/hemoglobina całkowita: Synonyms: Hemoglobina Barta/Hemoglobina całkowita |
pt-BR | Portuguese (Brazil) | Hemoglobina Barts/Hemoglobina.total: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Гемоглобин Barts/Гемоглобин.общий: Synonyms: Количественный Кровь Кровь сухая капля Массовая доля Точка во времени; |
tr-TR | Turkish (Turkey) | Hemoglobin Barts/Hemoglobin.total: |
zh-CN | Chinese (China) | 血红蛋白 Barts/血红蛋白.总计: Synonyms: Bart Bart's Hgb Barts MFr 全体数量 全血斑点(滤纸); |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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