54163-1

Cytomegalovirus DNA [#/volume] (viral load) in Urine by Probe and target amplification method detection limit = 200 copies/ml

Active

Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cytomegalovirus DNA:NCnc:Pt:Urine:Qn:Probe.amp.tar detection limit = 200 copies/mL
Long Common Name: Cytomegalovirus DNA [#/volume] (viral load) in Urine by Probe and target amplification method detection limit = 200 copies/ml
Short Name: CMV DNA # Ur NAA DL=200
Display Name: CMV DNA NAA+probe DL = 200 copies/ml (U) [#/Vol]
Consumer Name Alpha Get Info: Cytomegalovirus (CMV), Urine

Part Model Get Info

Component
Cytomegalovirus DNA
LP37883-3
- Analyte
  Cytomegalovirus DNA
  LP37883-3
  - Component Numerator
    Cytomegalovirus DNA
    LP37883-3
    - Component Numerator Core
      Cytomegalovirus
      LP14255-1
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NCnc
LP6836-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Probe.amp.tar detection limit = 200 copies/mL
LP57624-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.27
Last Updated: Version 2.70 (MIN)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG34273-9	Cytomegalovirus DNA\|NCnc\|Sys:ANYGU
LG36512-8	Cytomegalovirus DNA\|NCnc\|Urine

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytomegalovirus DNA:Početní koncentrace:Časový bod:Moč:Kvantitativní:Amplifikace nukleových kyselin limit detekce = 200 kopií/mL
de-DE	German (Germany)	Cytomegalie-Virus DNA:Anzahl pro Volumen:Zeitpunkt:Urin:Quantitativ:Zielfragmentamplifikation Nachweisgrenze = 200 Kopien/ml Synonyms: CMV
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός DNA:NCnc:Pt:Ούρα:Qn:Όριο ανίχνευσης δείκτη ενίσχυσης στόχου = 200 αντίγραφα/mL Synonyms: DNA MICRO NCnc Pt Qn Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Κυτταρομεγαλοϊός Όριο ανίχνευσης δείκτη ενίσχυσης στόχου = 200 αντίγραφα/mL Ούρα
es-ES	Spanish (Spain)	Citomegalovirus ADN:Concentración de número:Punto temporal:Orina:Qn:Sonda con objetivo límite de detección de amplificación = 200 copies/ml Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	ADN de citomegalovirus:Concentración numérica:Punto temporal:Orina:Cuantitativo:Límite de detección de amplificación de ácido nucleico = 200 copias / ml
fr-CA	French (Canada)	Cytomégalovirus, ADN:Concentration numérique:Temps ponctuel:Urine:Quantitatif:Sonde avec limite de détection de l'amplification = 200 copies/mL
fr-FR	French (France)	Cytomégalovirus ADN:Nombre/Volume:Ponctuel:Urine:Numérique:PCR amplification de cible,limite de détection=200 copies/mL
fr-BE	French (Belgium)	Cytomégalovirus ADN:Concentration numérique:Temps ponctuel:Urine:Quantitatif:Sonde avec limite de détection de l'amplification = 200 copies/mL Synonyms: CMV
it-IT	Italian (Italy)	Citomegalovirus DNA:NCnc:Pt:Urine:Qn:Sonda.amp.tar limite rilevamento = 200 copie/mL Synonyms: Concentrazione Numerica Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda con limite di rilevamento dell''amplificazio Sonda di DNA
nl-NL	Dutch (Netherlands)	Cytomegalovirus DNA:aantal/volume:moment:urine:kwantitatief:probe-detectie met detectielimiet = 200 copies/mL Synonyms: probe.amp.tar probe.amp.tar detectielimiet = 200 copies/mL
pt-BR	Portuguese (Brazil)	Cytomegalovírus DNA:#N/A:Pt:Urina:Qn:Sonda com limite de detecção da amplificação de alvo = 200 cópias/mL Synonyms: Deoxyribonucleic acid; CMV; Cytomgal; Cytomegalo virus; #; Number concentration; Count/mass; Count; AcS; CT; Acsolute; Acsolutes; Cnt; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; PCR DL=200; PCR DL=200; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Microbiology; Viral load
tr-TR	Turkish (Turkey)	Cytomegalovirus DNA:SayKons:Zmlı:İdrar:Kant:Porb.amf.hdf saptama sınırı = 200 kopya/mL
zh-CN	Chinese (China)	巨细胞病毒 DNA:计数型浓度:时间点:尿液:定量型:探针法.基因扩增.靶向检测极限 = 200 拷贝/毫升 Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法检测极限 = 200 拷贝/毫升;探针法.基因扩增.靶向检测极限 = 200 copies/mL;靶向扩增探针法检测极限 = 200 copies/mL;靶向扩增探针法检测极限 = 200 拷贝/毫升借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性数量型浓度探针法.基因扩增.靶向数量型浓度探针法.扩增.靶向数量或计数型浓度探针法.扩增.靶向时刻;随机;随意;瞬间病毒负荷病毒负荷量病毒负载病毒载量病毒载量（Viral load）经过扩增的脱氧核糖核酸探针计数型浓度探针法.基因扩增.靶向计数型浓度探针法.扩增.靶向

Example Units

Unit	Source
{copies}/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=54163-1

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.