Version 2.78

Part Description

LP30825-1   Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378 Source: Regenstrief LOINC

Fully-Specified Name

Component
Guanidinoacetate
Property
SCnc
Time
Pt
System
CSF
Scale
Qn
Method

Additional Names

Long Common Name
Guanidinoacetate [Moles/volume] in Cerebral spinal fluid
Short Name
Guanidinoacetate CSF-sCnc
Display Name
Guanidinoacetate (CSF) [Moles/Vol]
Consumer Name Alpha Get Info
Guanidinoacetate, Spinal fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.27
Last Updated
Version 2.70
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
79288-7 Creatine and guanidinoacetate panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Guanidinoacetat:Stoffmengenkonzentration:Zeitpunkt:Liquor:Quantitativ:
Synonyms: Zerebrospinalflüssigkeit
es-ES Spanish (Spain) Guanidinoacetato:Concentración de sustancia:Punto temporal:Líquido Cefalorraquideo:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Guanidinoacetato:Concentración de sustancias:Punto temporal:Fluído espinal cerebral:Cuantitativo:
et-EE Estonian (Estonia) Guanidinoatsetaat:SCnc:Pt:CSF:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Liikvor
fr-CA French (Canada) Guanidinoacétate:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
fr-FR French (France) Guanidinoacétate:Moles/Volume:Ponctuel:Liquide céphalorachidien:Numérique:
fr-BE French (Belgium) Guanidinoacétate:Concentration de substance:Temps ponctuel:LCR:Quantitatif:
it-IT Italian (Italy) Guanidinoacetato:SCnc:Pt:LCS:Qn:
Synonyms: Chimica Concentrazione di Sostanza Liquido cerebrospinale Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) guanidinoacetaat:mol/volume:moment:liquor cerebrospinalis:kwantitatief:
pt-BR Portuguese (Brazil) Guanidinoacetato:#N/A:Pt:LCR:Qn:
Synonyms: glycocyamine; guanidoacetic acid; guanidinoacetic acid; GAA; Substance concentration; Level; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU Russian (Russian Federation) Гуанидинацетат:МолКонц:ТчкВрм:ЦСЖ:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Guanidinoasetat:SubKons:Zmlı:BOS:Kant:
zh-CN Chinese (China) 胍基乙酸:物质的量浓度:时间点:脑脊液:定量型:
Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 GAA;胍乙酸;胍基醋酸 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

Example Units

Unit Source
umol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=54287-8