Version 2.78

Part Descriptions

LP14377-3   Aldosterone
Aldosterone is a steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It is the sole endogenous member of the class of mineralocorticoids. Acting on mineralocorticoid receptors (MR) on principal cells in the collecting ducts of the kidneys, it increases the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. Aldosterone also stimulates H+ secretion by intercalated cells in the collecting duct, regulating plasma bicarbonate (HCO3-) levels and its acidbase balance. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Aldosterone (Wikipedia)

LP14377-3   Aldosterone
Used to detect hyper and hypo aldosteronisnm. Hypoaldosteronism can occur in any condition that causes destruction or dysfunction of the adrenal gland.1,2,4 Hypoaldosterism can be due to primary adrenal insufficiency , congenital adrenal hypoplasia, acquired secondary aldosterone deficiency (hyporeninemic hypoaldosteronism), and acquired Hyporeninemic hypoaldosteronism is the most common form of isolated hypoaldosteronism and is results from impaired renin release from the kidney. Congenital hypoaldosteronism caused by inherited enzymatic defects in aldosterone biosynthesis are rare. Corticosterone methyloxidase I (CMO I) deficiency is associated with elevated serum levels of corticosterone and low levels of 18-hydroxy-corticosterone and aldosterone. Corticosterone methyloxidase II (CMO II) deficiency produces high levels of 18-hydroxy-corticosterone, the immediate precursor of aldosterone.
Acquired primary hypoaldosteronism can be caused by the administration of heparin. Also, persistently hypotensive, critically ill patients with sepsis, pneumonia, peritonitis, cholangitis, and liver failure can have inappropriately low plasma aldosterone concentrations in relation to elevated plasma renin activity. Primary hyperaldosteronism, also referred to as Conn syndrome, is due to overproduction of aldosterone by one or both of the adrenal glands. Some recent studies suggest that 10% to 15% of Hyper thyroidism cases are due to (or associated with ) primary hyperaldosteronism. Secondary hyperaldosteronism is relatively common and can occur as the result of any condition that decreases blood flow to the kidneys (ie, renal artery stenosis), decreases blood pressure, or lowers plasma sodium levels. Secondary hyperaldosteronism may also be seen with cirrhosis, congestive heart failure. and toxemia of pregnancy. Several studies have suggested that high-normal aldosterone levels predict development of high blood pressure in normotensive subjects and that increased aldosterone action contributes to hypertension, cardiovascular fibrosis, and cardiac hypertrophy. Source: Regenstrief Institute

Fully-Specified Name

Component
Aldosterone^15M post XXX challenge
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Aldosterone [Moles/volume] in Serum or Plasma --15 minutes post XXX challenge
Short Name
Aldost 15M p chal SerPl-sCnc
Display Name
Aldosterone 15 Min post Unsp challenge [Moles/Vol]
Consumer Name Alpha Get Info
Aldosterone 15 min after challenge, Blood

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC Group Group Name
LG50715-8 Aldosterone^15M post XXX challenge|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Aldosterona^15 minutos pos provocación XXX:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Aldosterona ^15M después del desafío XXX:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Aldosteroon^15 minutiti pärast XXX manustamist:SCnc:Pt:S/P:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Aldostérone^15 min post test de provocation XXX:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Aldostérone T15min après épreuve:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Aldostérone^15 min post test de provocation XXX:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Aldosterone^15Minuti post XXX provocazione:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: 15 minuti dopo XXX stimolo Concentrazione di Sostanza dopo XXX provocazione Plasma Punto nel tempo (episodio) Siero Siero o Plasma Stimolo Test di provocazione
nl-NL Dutch (Netherlands) aldosteron^15 min na XXX belasting:mol/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Aldosterona^15 min após administração de XXX:#N/A:Pt:Sor/Plas:Qn:
Synonyms: ; Aldost; 15M p chal; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; PST; After; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
ru-RU Russian (Russian Federation) Альдостерон^15 минут после XXX пробы:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Провокационная проба Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Aldosteron^15dk snr XXX girişimi:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 醛固酮^在XXX刺激之后15分钟:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 15Min之后于XXX刺激;15Min之后于此处不作说明的刺激;15分钟之后于XXX刺激;15分钟之后于此处不作说明的刺激;在XXX刺激之后15Min;在此处不作说明的刺激之后15Min;在此处不作说明的刺激之后15分钟 XXX刺激 - 在...之后 XXX刺激因素 之后于 XXX 刺激;之后于 XXX 刺激因素;之后于此处不作说明的刺激;之后于此处不作说明的刺激因素;在 XXX 刺激因素之后;在此处不作说明的刺激之后;在此处不作说明的刺激因素之后 之后于... 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 刺激因素;挑战 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 时刻;随机;随意;瞬间 此处不作说明的刺激 此处不作说明的刺激因素 血清或血浆 醛基甾酮;醛甾酮;醛皮质酮;醛类脂醇

Example Units

Unit Source
pmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=57589-4