57613-2
5-Alpha tetrahydrocortisol [Mass/volume] in 24 hour Urine --pre high dose dexamethasone
Active
Part Description
LP97520-8 5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, 5-Alpha tetrahydrocortisol
Fully-Specified Name
- Component
- 5-Alpha tetrahydrocortisol^pre high dose dexamethasone
- Property
- MCnc
- Time
- 24H
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- 5-Alpha tetrahydrocortisol [Mass/volume] in 24 hour Urine --pre high dose dexamethasone
- Short Name
- 5-A THF pre hi Dex 24h Ur-mCnc
- Display Name
- 5-Alpha tetrahydrocortisol pre high dose dexamethasone (24H U) [Mass/Vol]
- Consumer Name Alpha Get Info
- 5-Alpha tetrahydrocortisol before high dose dexamethasone, Urine
Basic Attributes
- Class
- CHAL
- Type
- Laboratory
- First Released
- Version 2.29
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | 5-α-τετραϋδροκορτιζόλη^προ υψηλής δόσης δεξαμεθαζόνης: Synonyms: 5-α-τετραϋδροκορτιζόλη MCnc Δεξαμεθαζόνη Τετραϋδροκορτιζόλη |
| es-ES | Spanish (Spain) | 5-Alfa tetrahidrocortisol^pre alta dosis de dexametasona: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 5-alfa tetrahidrocortisol^ antes de dosis altas de dexametasona: |
| fr-CA | French (Canada) | 5-alpha tétrahydrocortisol^pré dexaméthasone forte dose: |
| fr-FR | French (France) | 5-alpha tétrahydrocortisol avant dexaméthasone fort: |
| fr-BE | French (Belgium) | 5-Alpha tétrahydrocortisol^pre dexamethasone haute dose: Synonyms: avant haute dose de Dexamethasone |
| it-IT | Italian (Italy) | 5-Alfa tetraidrocortisolo^pre dose elevata desametasone: Synonyms: 24 Ore Alta dose Concentrazione di Massa prima di dose elevata di desametasone Test di provocazione |
| nl-NL | Dutch (Netherlands) | 5-alfa-tetrahydrocortisol^voor hoge dosis dexamethason: Synonyms: 24U |
| pt-BR | Portuguese (Brazil) | 5-Alfa tetrahidrocortisol^pré alta dose de dexametasona: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | 5-Альфа тетрагидрокортизол^до высокой дозы дексаметазона: Synonyms: Количественный Массовая концентрация |
| tr-TR | Turkish (Turkey) | 5-Alfa tetrahidrokortizol^önc dekzametazon dozu yüksek: |
| zh-CN | Chinese (China) | 5-Alpha 四氢皮质醇^在给予高剂量地塞米松之前: Synonyms: 1天; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
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