Version 2.80

Part Description

LP97520-8   5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database , 5-Alpha tetrahydrocortisol

Fully-Specified Name

Component
5-Alpha tetrahydrocortisol^2D post high dose dexamethasone
Property
MRat
Time
24H
System
Urine
Scale
Qn
Method

Additional Names

Long Common Name
5-Alpha tetrahydrocortisol [Mass/time] in 24 hour Urine --2 days post high dose dexamethasone
Short Name
5-A THF 2D p high Dex 24h Ur-mRate
Display Name
5-Alpha tetrahydrocortisol 2 days post high dose dexamethasone (24H U) [Mass/Time]
Consumer Name Alpha Get Info
5-Alpha tetrahydrocortisol 2 days after high dose dexamethasone, Urine

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) 5-α-τετραϋδροκορτιζόλη^2 ημέρες κατόπιν υψηλής δόσης δεξαμεθαζόνης:MRat:24H:Ούρα:Qn:
Synonyms: 5-α-τετραϋδροκορτιζόλη MRat Δεξαμεθαζόνη Τετραϋδροκορτιζόλη
es-ES Spanish (Spain) 5-Alfa tetrahidrocortisol^2D pos dosis alta de dexametasona:Indice de masa:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 5-alfa tetrahidrocortisol^2D después de dosis altas de dexametasona:Tasa de masa:24H:Orina:Cuantitativo:
fr-CA French (Canada) 5-alpha tétrahydrocortisol^2 j dexaméthasone post forte dose:Débit de masse:24 h:Urine:Quantitatif:
fr-FR French (France) 5-alpha tétrahydrocortisol TJ02 après dexaméthasone fort:Masse/Temps:24H:Urine:Numérique:
fr-BE French (Belgium) 5-Alpha tétrahydrocortisol^après haute dose de Dexaméthasone. 2j après:Débit de masse:24 h:Urine:Quantitatif:
it-IT Italian (Italy) 5-Alfa tetraidrocortisolo^2 gg post dose elevata desametazone:MRat:24h:Urine:Qn:
Synonyms: 2 giorni dopo dose elevata di desametazone;2die po 24 Ore Alta dose dopo dose elevata di desametasone Indice di Massa Test di provocazione
nl-NL Dutch (Netherlands) 5-alfa-tetrahydrocortisol^2 dagen na hoge dosis dexamethason:massa/tijd:24 uur:urine:kwantitatief:
Synonyms: 24U 2D na hoge dosis dexamethason
pt-BR Portuguese (Brazil) 5-Alfa tetrahidrocortisol^2 dias após alta dose de dexametasona:#N/A:24H:Urina:Qn:
Synonyms: ; THF; THC; Decadron; Dexameth; Dexone; Hexadrol; 5-A THF; 5A-tetrahydrocortisol; 2D p high Dex; mRate; Mass rate; 1 day; 24 hours; 24HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; PST; After; Alfa; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
ru-RU Russian (Russian Federation) 5-Альфа тетрагидрокортизол^2 дня после высокой дозы дексаметазона:МассСк:24 часа:Моча:Колич:
Synonyms: Количественный Массовая скорость
tr-TR Turkish (Turkey) 5-Alfa tetrahidrokortizol^2G snr yüksek doz dekzametazon:KütlHz:24Sa:İdrar:Kant:
zh-CN Chinese (China) 5-Alpha 四氢皮质醇^在给予高剂量地塞米松之后2天:质量速率:24小时:尿液:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 2D之后于给予高剂量地塞米松;2天之后于给予高剂量地塞米松;48Hr之后于给予高剂量地塞米松;48小时之后于给予高剂量地塞米松;在给予高剂量地塞米松之后2D;在给予高剂量地塞米松之后48Hr;在给予高剂量地塞米松之后48小时 5 Alpha-四氢皮质甾醇 5 Alpha-四氢皮醇 5-A 四氢皮质醇;5-α 四氢皮质醇;5-alpha（α、A） 四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇） 5α-四氢皮质甾醇 5α-四氢皮质醇 5α-四氢皮醇 9α氟16甲基脱氢皮质甾醇;氟甲强的松龙;氟美松;甲氟烯索 THC;THF;四氢皮质甾醇;四氢皮醇 XXX刺激 - 在...之后 α 一剂物质 一剂药物 之后于... 之后于给予高剂量地塞米松 剂量物质 单位时间内的质量数;质量速率(单位时间) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 尿;小便;下泉 阿尔法 高剂量

Example Units

Unit Source
mg/(24.h) Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=57616-5