57618-1
5-Alpha tetrahydrocortisol [Mass/time] in 24 hour Urine --pre dose dexamethasone
Active
Part Description
LP97520-8 5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, 5-Alpha tetrahydrocortisol
Fully-Specified Name
- Component
- 5-Alpha tetrahydrocortisol^pre dose dexamethasone
- Property
- MRat
- Time
- 24H
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- 5-Alpha tetrahydrocortisol [Mass/time] in 24 hour Urine --pre dose dexamethasone
- Short Name
- 5-A THF Pre Dex 24h Ur-mRate
- Display Name
- 5-Alpha tetrahydrocortisol pre dose dexamethasone (24H U) [Mass/Time]
- Consumer Name Alpha Get Info
- 5-Alpha tetrahydrocortisol before dose dexamethasone, Urine
Basic Attributes
- Class
- CHAL
- Type
- Laboratory
- First Released
- Version 2.29
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | 5-α-τετραϋδροκορτιζόλη^προ δόσης δεξαμεθαζόνης: Synonyms: 5-α-τετραϋδροκορτιζόλη MRat Δεξαμεθαζόνη Τετραϋδροκορτιζόλη |
es-ES | Spanish (Spain) | 5-Alfa tetrahidrocortisol^Pre dosis dexametasona: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 5-alfa tetrahidrocortisol^ predosis dexametasona: |
fr-CA | French (Canada) | 5-alpha tétrahydrocortisol^pré dose dexaméthasone: |
fr-FR | French (France) | 5-alpha tétrahydrocortisol avant dexaméthasone: |
fr-BE | French (Belgium) | 5-Alpha tétrahydrocortisol^Pré dose dexaméthasone: Synonyms: Avant dose |
it-IT | Italian (Italy) | 5-Alfa tetraidrocortisolo^pre dose desametasone: Synonyms: 24 Ore Indice di Massa prima di dose prima di dose di desametasone Test di provocazione |
nl-NL | Dutch (Netherlands) | 5-alfa-tetrahydrocortisol^voor dosis dexamethason: Synonyms: 24U |
pt-BR | Portuguese (Brazil) | 5-Alfa tetrahidrocortisol^pré dose de dexametasona: Synonyms: ; |
ru-RU | Russian (Russian Federation) | 5-Альфа тетрагидрокортизол^до дозы дексаметазона: Synonyms: Количественный Массовая скорость |
tr-TR | Turkish (Turkey) | 5-Alfa tetrahidrokortizol^önc dekzametazon dozu: |
zh-CN | Chinese (China) | 5-Alpha 四氢皮质醇^在给予地塞米松之前: Synonyms: 1天; |
Example Units
Unit | Source |
---|---|
mg/(24.h) | Example UCUM Units |
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