57619-9
5-Alpha tetrahydrocortisol [Mass/volume] in 24 hour Urine --2 days post dose dexamethasone
Active
Part Description
LP97520-8 5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, 5-Alpha tetrahydrocortisol
Fully-Specified Name
- Component
- 5-Alpha tetrahydrocortisol^2D post dose dexamethasone
- Property
- MCnc
- Time
- 24H
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- 5-Alpha tetrahydrocortisol [Mass/volume] in 24 hour Urine --2 days post dose dexamethasone
- Short Name
- 5-A THF 2D p Dex 24h Ur-mCnc
- Display Name
- 5-Alpha tetrahydrocortisol 2 days post dose dexamethasone (24H U) [Mass/Vol]
- Consumer Name Alpha Get Info
- 5-Alpha tetrahydrocortisol 2 days after dexamethasone, Urine
Basic Attributes
- Class
- CHAL
- Type
- Laboratory
- First Released
- Version 2.29
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | 5-α-τετραϋδροκορτιζόλη^2 ημέρες κατόπιν δόσης δεξαμεθαζόνης: Synonyms: 5-α-τετραϋδροκορτιζόλη MCnc Δεξαμεθαζόνη Τετραϋδροκορτιζόλη |
es-ES | Spanish (Spain) | 5-Alfa tetrahidrocortisol^2D pos dosis de dexametasona: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 5-alfa tetrahidrocortisol^2D posdosis dexametasona: |
fr-CA | French (Canada) | 5-alpha tétrahydrocortisol^2 j post dose dexaméthasone: |
fr-FR | French (France) | 5-alpha tétrahydrocortisol TJ02 après dexaméthasone: |
fr-BE | French (Belgium) | 5-Alpha tétrahydrocortisol^2 j post dose dexaméthasone: |
it-IT | Italian (Italy) | 5-Alfa tetraidrocortisolo^2 gg post dose desametazone: Synonyms: 2 giorni dopo soppressione con desametazone; |
nl-NL | Dutch (Netherlands) | 5-alfa-tetrahydrocortisol^2 dagen na dosis dexamethason: Synonyms: 24U 2D na dosis dexamethason |
pt-BR | Portuguese (Brazil) | 5-Alfa tetrahidrocortisol^2 dias após dose de dexametasona: Synonyms: ; |
ru-RU | Russian (Russian Federation) | 5-Альфа тетрагидрокортизол^2 дня после дозы дексаметазона: Synonyms: Количественный Массовая концентрация |
tr-TR | Turkish (Turkey) | 5-Alfa tetrahidrokortizol^2G snr dekzametazon dozu: |
zh-CN | Chinese (China) | 5-Alpha 四氢皮质醇^在给予剂量地塞米松之后2天: Synonyms: 1天; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
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