58390-6
2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP)/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
LP35885-0 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
EDDP (2-ethylidene-1,5-dimethyl1-3,3-diphenylpyrrolidine) is a primary metabolite of methadone, a synthetic opioid used for the treatment of opioid dependence. It is excreted in bile and urine along with other another methadone metabolite, EMPD. Levels of methadone itself are variable and depend on a patient's urine pH value, dose given, and metabolism. EDDP levels are less variable and can be detected 4 to 6 hours after methadone use, therefore, EDDP is preferentially used to check for methadone exposure.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- EDDP/Creat Ur
- Display Name
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP)/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP)/Creatinine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.30
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3156
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | 2-Ethyliden-1,5-Dimethyl-3,3-Diphenylpyrrolidin/Creatinin: |
es-ES | Spanish (Spain) | 2-etilideno-1,5-dimetil-3,3-difenilpirrolidina (EDDP)/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 2-etiliden-1,5-dimetil-3,3-difenilpirrolidina / creatinina: |
et-EE | Estonian (Estonia) | 2-etüülideen-1,5-dimetüül-3,3-difenüülpürolidiin/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-CA | French (Canada) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP)/Créatinine: |
fr-FR | French (France) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine/créatinine: |
fr-BE | French (Belgium) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP)/Créatinine: Synonyms: Rapport de masse |
it-IT | Italian (Italy) | 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina/Creatinina: Synonyms: 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina (ED Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa |
nl-NL | Dutch (Netherlands) | 2-ethylideen-1,5-dimethyl-3,3-difenylpyrrolidine/creatinine: Synonyms: kreatinine |
pt-BR | Portuguese (Brazil) | 2-Etilideno-1,5-Dimetil-3,3-Difenilpirrolidina/Creatinina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | 2-Этилиден-1,5-Диметил-3,3-Дифенил Пирролидин/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
tr-TR | Turkish (Turkey) | 2-Etiliden-1,5-Dimetil-3,3-Difenilpirrolidin/Kreatinin: |
zh-CN | Chinese (China) | 2-亚乙基-1,5-二甲基-3,3-四氢吡咯/肌酐: Synonyms: Ⅰ 2-乙叉-1,5-二甲基-3,3-吡咯烷; |
Example Units
Unit | Source |
---|---|
ug/g{creat} | Example UCUM Units |
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