59171-9
Norclozapine [Presence] in Urine
Active
Part Description
LP18081-7 Norclozapine
Norclozapine (desmethyl-clozapine),a major metabolite of clozapine, is pharmacologically active. The cytochrome P450 isoenzyme 1A2 is primarily responsible for clozapine metabolism, but 2C, 2D6, 2E1 and 3A3/4 appear to play roles as well. Agents which induce (e.g. cigarette smoke) or inhibit (e.g. theophylline, ciprofloxacin, fluvoxamine) CYP1A2 may increase or decrease, respectively, the metabolism of clozapine. For example, the induction of metabolism caused by smoking means that smokers require up to double the dose of clozapine compared with non-smokers to achieve an equivalent plasma concentration.
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Source: Wikipedia, Norclozapine
Fully-Specified Name
- Component
- Norclozapine
- Property
- PrThr
- Time
- Pt
- System
- Urine
- Scale
- Ord
- Method
Additional Names
- Long Common Name
- Norclozapine [Presence] in Urine
- Short Name
- Norclozapine Ur Ql
- Display Name
- Norclozapine Ql (U)
- Consumer Name Alpha Get Info
- Norclozapine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.32
- Last Updated
- Version 2.73
- Change Reason
- The Property has been changed from ACnc to reflect the new model for ordinal terms where results are based on a cut-off value.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4976
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Norclozapina: |
es-MX | Spanish (Mexico) | Norclozapina: |
et-EE | Estonian (Estonia) | Norklosapiin: Synonyms: Järgarvuline Juhuslik Uriin |
fr-CA | French (Canada) | Norclozapine: |
fr-FR | French (France) | Norclozapine: |
fr-BE | French (Belgium) | Norclozapine: |
it-IT | Italian (Italy) | Norclozapina: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | norclozapine: |
pt-BR | Portuguese (Brazil) | Norclozapina: |
ru-RU | Russian (Russian Federation) | Норклозапин: Synonyms: Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Norklozapin: Synonyms: Mevcut |
uk-UA | Ukrainian (Ukraine) | Норклозапін: Synonyms: Clozapine metabolite; |
zh-CN | Chinese (China) | 去甲基氯氮平: Synonyms: 依次型; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=59171-9
LOINC Copyright
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