Version 2.77

Part Description

LP28423-9   West Nile virus
The West Nile Virus (WNV) is an arbovirus that was first identified in the West Nile District of Uganda in 1937. In the fall of 1999, the National Veterinary Services Laboratory (NVLS) isolated WNV in a dead crow in New York City.(http://www.who.int/mediacentre/factsheets/fs354/en/) Over the following ten years, WNV spread throughout the United States, Canada, Mexico and the Carribbean. WNV is usually transmitted through the bite of the Culex mosquito, but can also be spread in blood transfusions, organ transplants, breast milk, intrauterine exposure and laboratory-acquired infections. Birds are the preferred host of WNV, and the American robin is an important amplifier host since it develops enough virus in its serum to infect feeding mosquitoes. Though most infections with WNV are subclinical for humans, between 2005 and 2009 there were 12,975 people infected with WNV, of which 35% had severe cases of neuroinvasive disease and 496 people died. For individuals who are 70 years of age or older, infection with WNV has a 15-29% fatality rate. For infants and immunocompromised patients infected with WNV, the fatality rate is even higher. Diagnosis of WNV is based on clinical symptoms and antibody titers. The IgM antibody-capture enzyme-linked immunosorbent assay (MAC-ELISA) is the key method used to diagnosis WNV in clinical settings. Antibody titers to WNV NS5 are detectable long-term in vivo and can be used to distinguish past infection with WNV from current infection. RNA is usually undetectable in serum after 13.2 days, but on rare occasions, has been found in serum beyond 40 days. Treatment of infection with WNV is mostly supportive. There are no FDA-approved drugs or vaccines available. PMID: 12089283 PMID: 23034323 Source: Regenstrief LOINC

Fully-Specified Name

Component
West Nile Virus Ab.IgG avidity
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IA

Additional Names

Short Name
WNV IgG Avidity Ser Ql IA
Display Name
West Nile virus IgG avidity IA Ql (S)
Consumer Name Alpha Get Info
West Nile virus IgG avidity, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.34
Last Updated
Version 2.56
Change Reason
Property has been changed from ACnc to reflect the fact that the definition of high or low avidity is determined by a defined cut-off point (threshold); The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32768-0 West Nile virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) West-Nil-Virus Ak.IgG-Avidität:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunoassay
es-ES Spanish (Spain) Virus Nilo Occidental Avidez IgG:PrThr:Punto temporal:Suero:Ord:IA
es-MX Spanish (Mexico) Avidez por Ab.IgG del virus del Nilo Occidental:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
fr-CA French (Canada) Virus du Nil occidental , Ac.avidité des IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FR French (France) West Nile virus Ac IgG avidité:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
fr-BE French (Belgium) Virus du Nil occidental Anticorps.avidité des IgG:PrThr:Temps ponctuel:Sérum:Ordinal:IA
Synonyms: Anticorps
it-IT Italian (Italy) Nilo occidentale, virus Ab.avidità IgG:PrThr:Pt:Siero:Ord:IA
Synonyms: anticorpi IgG anticorpo Avidità delle IgG; test avidità delle IgG Immunoassay Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Virus del Nilo occidentale
nl-NL Dutch (Netherlands) West-Nijlvirus As.IgG-aviditeit:aanwezigheid:moment:serum:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA IgG Bindingskracht
pl-PL Polish (Poland) Wirus gorączki zachodniego Nilu Ab.IgG awidność:granica wykrywalności:punkt w czasie:surowica:półilościowy:metoda immunologiczna
Synonyms: IgG Przeciwciała do wirusa gorączki zachodniego Nilu Przeciwciała IgG do wirusa gorączki zachodniego Nilu Przeciwciała IgG do wirusa gorączki zachodniego Nilu awidność
pt-BR Portuguese (Brazil) Vírus do Nilo Ocidental Ac.IgG avidez::Pt:Soro:Ord:Imunoensaio
ru-RU Russian (Russian Federation) Западный Нил вирус Ат.IgG авидность:PrThr:ТчкВрм:Сыв:Пор:IA
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Batı Nil virüsü Ab.IgG avidite:MevcEşik:Zmlı:Ser:Srl:İA
Synonyms: Ak Ak.IgG Ak.IgG avidite İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) 西尼罗河病毒 抗体.IgG 亲合力:存在情况或阈值:时间点:血清:序数型:免疫测定法
Synonyms: Ab.IgG 亲合力;IgG 亲合力;抗体 IgG 亲合力 Ab.IgG;IgG;抗体 IgG Ab;自身抗体 WNV Ab WNV Ab.IgG WNV 抗体 WNV 抗体.IgG WNV;西尼罗河热;西尼罗河热病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 西尼罗河热病毒 Ab 西尼罗河热病毒 Ab.IgG 西尼罗河热病毒抗体 西尼罗河热病毒抗体.IgG 西尼罗河病毒 Ab 西尼罗河病毒 Ab.IgG 西尼罗河病毒 IgG

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=60028-8