6014-5

von Willebrand factor (vWf) actual/normal in Platelet poor plasma by Aggregometry.ristocetin cofactor activity

Active

Part Description

LP16906-7 von Willebrand factor
Von Willebrand factor (vWF) is a high-molecular-weight plasma protein produced by endothelial cells and megakaryocytes. It is part of the factor VIII/vWF complex. The vWF has receptors for collagen, platelets, and ristocetin. Ristocetin is an antibiotic, previously used to treat staphylococcal infections, now mainly used in vitro to diagnose conditions such as von Willebrand disease. Platelet agglutination caused by ristocetin can occur only in the presence of von Willebrand factor multimers, so if ristocetin is added to blood lacking the factor it will not coagulate. The vWF facilitates the adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in von Willebrand's disease is due to the deficiency of this factor. Source: National Library of Medicine, MeSH 2006

Reference Information

Type	Source	Reference
Mapping Guidance	Regenstrief Help	Measures the activity of vWF protein, reported as a % of normal in the presence of Ristocetin. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

LOINC Names Get Info

Fully-Specified Name: von Willebrand factor actual/Normal:RelTime:Pt:PPP:Qn:Aggregometry.ristocetin cofactor activity
Long Common Name: von Willebrand factor (vWf) actual/normal in Platelet poor plasma by Aggregometry.ristocetin cofactor activity
Short Name: vWF Act/Nor PPP Aggr Rst act
Display Name: vWf actual/normal Aggregometry.ristocetin cofactor activity (PPP) [Relative time]
Consumer Name Alpha Get Info: vWf actual/normal, Blood

Part Model Get Info

Component
von Willebrand factor actual/Normal
LP449903-6
- Analyte
  von Willebrand factor actual/Normal
  LP449903-6
  - Component Numerator
    von Willebrand factor actual/Normal
    LP449903-6
    - Component Numerator Core
      von Willebrand factor
      LP16906-7
    - Component Numerator Core Suffix
      actual/normal
      LP29333-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
RelTime
LP21276-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
PPP
LP7494-0
- System Core
  PPP
  LP7494-0
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Aggregometry.ristocetin cofactor activity
LP449902-8

Basic Attributes

Class: COAG
Type: Laboratory
First Released: Version 1.0d
Last Updated: Version 2.82 (NAM)
Change Reason: Changed Order_Obs from 'Observation Only' to fit the current order use cases.; Updated Method from 'Aggr' to 'Platelet aggr' because the two are duplicates and 'Platelet aggr' is more commonly used in LOINC
Order vs. Observation: Both
Common Test Rank Get Info: 2267

Member of these Panels

LOINC	Long Common Name
44791-2	Menorrhagia coagulation panel - Platelet poor plasma
48593-8	von Willebrand panel - Platelet poor plasma

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	von Willebrandův faktor (vWf).ristocetinový kofaktor aktivita aktuální/normální:Relativní čas:Časový bod:Plazma chudá na trombocyty:Kvantitativní:Agregace trombocytů
de-AT	German (Austria)	Synonyms: vWF-Ristocetin Kofaktor Aktivität
de-DE	German (Germany)	von Willebrand-Faktor Messwert/Normalwert:Zeitverhältnis:Zeitpunkt:Thrombozytenarmes Plasma:Quantitativ:Aggregometrie.Ristocetin-Cofaktor-Aktivität
el-GR	Greek (Greece)	παράγοντας Von Willebrand.δραστηριότητα συμπαράγοντα ριστοσετίνης πραγματικό/φυσιολογικό:RelTime:Pt:PPP:Qn:Συγκ αιμοπεταλίων Synonyms: COAG PPP Pt Qn RelTime Δραστηριότητα παράγοντας Von Willebrand παράγοντας Von Willebrand.δραστηριότητα συμπαράγοντα ριστοσετίνης παράγοντας Von Willebrand.συμπαράγοντας ριστοσετίνης πραγματικό/φυσιολογικό Ριστοσετίνη Συγκ αιμοπεταλίων
es-AR	Spanish (Argentina)	factor de von Willebrand.actividad del cofactor de ristocetina:tiempo relativo:punto en el tiempo:plasma desplaquetado:cuantitativo:agregación
es-ES	Spanish (Spain)	Factor Von Willebrand. Actividad del cofactorde la ristocetina actual/normal:Tiempo relativo:Punto temporal:Plasma pobre en plaquetas:Qn:Agregación plaquetaria Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Factor de von Willebrand Actividad del cofactor de ristocetina real / Normal:Tiempo relativo:Punto temporal:Plasma pobre en plaquetas:Cuantitativo:La agregación plaquetaria
fr-CA	French (Canada)	Cofacteur de la ristocétine.facteur de von Willebrand, Mesuré/normal:Temps relatif:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Agrégation plaquettaire
fr-FR	French (France)	Facteur Willebrand activité cofacteur ristocétine Patient (%):Temps relatif:Ponctuel:Plasma pauvre en plaquettes:Numérique:Agrégation plaquettaire
fr-BE	French (Belgium)	Cofacteur de la ristocétine.facteur de von Willebrand Mesuré/normal:Temps relatif:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Agrégation plaquettaire Synonyms: Fvw Mesuré/normal
it-IT	Italian (Italy)	von Willebrand, fattore effettivo/normale:RelTime:Pt:PPP:Qn:Aggregometria.attività del cofattore ristocetinico Synonyms: Fattore di von Willebrand (vWf) Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione Tempo Relativo
ko-KR	Korean (Korea, Republic Of)	폰 빌레브란트 인자.리스토세틴 보조인자 활성도 실제값/정상범위:상대시간:검사시점:혈소판제거혈장:정량:응집
nl-NL	Dutch (Netherlands)	von Willebrand-factor.ristocetinecofactor activiteit gemeten/normaal:relatieve tijd:moment:plaatjesarm plasma:kwantitatief:trombocytenaggregatie Synonyms: coagulatiemethode gemeten/normaal plaatjesaggregatie
pl-PL	Polish (Poland)	Czynnik von Willebranda.aktywność kofaktora rystocetyny badane/prawidłowe:względna jednostka czasu:punkt w czasie:osocze ubogopłytkowe:ilościowy:agregacja płytek Synonyms: Czynnik von Willebranda (vWf) Czynnik von Willebranda aktywność kofaktora rystocetyny PPP
pt-BR	Portuguese (Brazil)	Fator Von Willebrand.Cofator Ristocetina atividade verdadeira/Normal:RelTime:Pt:PPPQ:Qn:Agregação Synonyms: ; vWf:RCo; Von willebrand factor activity; vWf Activity; vWf:RCo; Risto; AggRecetin; Movements; Nor; RlTm; Point in time; Random; Platelet poor plasma; Plas; Quantitative; QNT; Quant; Quan; Aggregation; Agg; Aggreg; Act/Nor; Vonwillebrand; Von will; Control; Fac; Fact; Cofact; Actvty; Activ; COAGULATION
tr-TR	Turkish (Turkey)	von Willebrand faktörü.ristocetin kofaktör aktivitesi gerçek/normal:GörZmn:Zmlı:TFkP:Kant:Trombosit agreg
zh-CN	Chinese (China)	von Willebrand 因子.瑞斯托菌素辅助因子活性实际的/正常的:相对时间:时间点:贫血小板血浆:定量型:血小板聚集试验法 Synonyms: PAgT;PAgT 法;聚集试验;聚集试验法;血小板聚集;血小板聚集法;血小板聚集试验 von Willebrand von Willebrand 因子（von Willebrand Factor，vWf）;vWf;vWf 因子;血管性假血友病因子;血管性血友病因子 von Willebrand 因子（vWf 因子、血管性假血友病因子、血管性血友病因子）.瑞斯托菌素辅助因子活性;von Willebrand 因子.瑞斯托菌素辅助因子（利托菌素辅助因子、瑞斯托菌素辅因子、瑞斯托霉素辅助因子、瑞斯西丁素辅助因子、Ristocetin 因子）活性;von Willebrand 因子.瑞斯托菌素辅助因子 von willebrand因子（vWf 因子、血管性假血友病因子、血管性血友病因子）.瑞斯托菌素辅助因子;von willebrand因子.瑞斯托菌素辅助因子（利托菌素辅助因子、瑞斯托菌素辅因子、瑞斯托霉素辅助因子、瑞斯西丁素辅助因子、Ristocetin 因子）;vWf 因子瑞斯托菌素辅助因子乏血小板血浆;Platelet poor plasma;PPP 冯·威勒布兰德冯威勒布兰德冯威勒布兰德氏凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程利托菌素;瑞斯托霉素;瑞斯西丁素;瑞期托菌素;Ristocetin 可用数量表示的;定量性;数值型;数量型;连续数值型标尺因素实测值实测值/正常值;实际/正常;实际值/正常值;实际测定值/正常值实测的实际值对照对照标准对照物对照的时刻;随机;随意;瞬间正常的活动系数辅因子

Example Units

Unit	Source
%	Example UCUM Units
%	REGENSTRIEF

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=6014-5

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.