61411-5
Desipramine/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP16103-1 Desipramine
Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin ® and Pertofrane ®. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. Along with other tricyclics, desipramine has found use in treating neuropathic pain. The mechanism of action seems to involve the activation, through norepinephrine reuptake inhibition, of descending pathways in the spinal cord that block pain signals from ascending to the brain. Desipramine is one of the most potent and selective medications in this respect. Some evidence suggests that desipramine may help with ADD. See also:antidepressant tricyclic antidepressant External links:Desipramine - medicinenet.comDesipramine - medlineplus.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Desipramine (Wikipedia)
LP16103-1 Desipramine
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Source: National Library of Medicine, MeSH 2006
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- Desipramine/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Desipramine/Creatinine [Mass Ratio] in Urine
- Short Name
- Desipramine/Creat Ur
- Display Name
- Desipramine/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Desipramine/Creatinine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5658
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Δεσιπραμίνη/Κρεατινίνη: Synonyms: MRto Δεσιπραμίνη Κρεατινίνη |
es-MX | Spanish (Mexico) | Desipramina / Creatinina: |
es-ES | Spanish (Spain) | Desipramina/Creatinina: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Desipramiin/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-CA | French (Canada) | Désipramine/Créatinine: |
fr-FR | French (France) | Désipramine/créatinine: |
fr-BE | French (Belgium) | Désipramine/Créatinine: Synonyms: Rapport de masse |
it-IT | Italian (Italy) | Desipramina/Creatinina: Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa |
nl-NL | Dutch (Netherlands) | desipramine/creatinine: Synonyms: kreatinine |
pt-BR | Portuguese (Brazil) | Desipramina/Creatinina: |
ru-RU | Russian (Russian Federation) | Дезипрамин/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
tr-TR | Turkish (Turkey) | Desipramin/Kreatinin: |
zh-CN | Chinese (China) | 去甲丙咪嗪/肌酐: Synonyms: C18H22N2; |
Example Units
Unit | Source |
---|---|
ug/g{creat} | Example UCUM Units |
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