62641-6

PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701

Discouraged

Status Information

Status: DISCOURAGED

Term Description

A biospecimen is collected from the respondent to measure cotinine, a marker of either smoking or of environmental tobacco smoke exposure. One of the most common methods is via a urine sample obtained from the respondent. Cotinine in urine is measured by gas chromatography mass spectrometry (GC-MS). Other biological matrices (blood, hair, saliva) may be used to measure cotinine. Information about collection and analysis of those matrices is found in the Supplemental Information: Blood, Hair, and Saliva Assays for Tobacco Smoke Exposure. Caffeine may interfere with the accuracy of the results. During the gas chromatography analysis, this interference can be minimized by ramping up the temperature and eluting the caffeine later than the cotinine.

Reference Information

Type	Source	Reference
Article	Consensus measures for Phenotypes and Exposures	Man, C. N., L.-H. Gam, Ismail, S., Lajis, R., Awang, R. 2006. Simple, rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry. J of Chromatography B 844(2): 322-327.
Article	Consensus measures for Phenotypes and Exposures	Bernowitz, N.L. (1999). Biomarkers of Environmental Tobacco Smoke Exposure. Environ Health Perspect. 107(Suppl 2):3 49-355.
Article	Consensus measures for Phenotypes and Exposures	Kuo, H.W., Yang, J.S., Chiu, M.C. (2002). Determination of urinary and salivary cotinine using gas and liquid chromatography and enzyme-linked immunosorbent assay. J Chromatogr B Analyt Technol Biomed Life Sci. 768(2):297-303.
Article	Consensus measures for Phenotypes and Exposures	Dhar, Preeti. (2004). Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods. J Pharm Biomed Anal, 35(2004), 155-168.
Article	Consensus measures for Phenotypes and Exposures	Benowitz, Neal L. (1996). Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiol Rev, 18(2), 188-204.

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC	Name	R/O/C	Cardinality	Example UCUM Units
62641-6	PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Indent10366-3	Cotinine [Mass/volume] in Urine	O		ng/mL

LOINC Names Get Info

Fully-Specified Name: PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701:-:Pt:^Patient:-:PhenX
Long Common Name: PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Short Name: Resp urine assay smoke exp proto

Part Model Get Info

Component
PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
LP111925-6
- Analyte
  PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
  LP111925-6
  - Component Numerator
    PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
    LP111925-6
    - Component Numerator Core
      PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
      LP111925-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
-
LP6769-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
^Patient
LP310005-6
- System Core
  NULL
- Super System
  Patient
  LP6985-8
Scale
-
LP7747-1
Method
PhenX
LP95333-8

Survey Question

: PX091701

Code System	Code	Code Text	Code Version
PhenX (Consensus measures for Phenotypes and Exposures)	91701	biomarker_of_exposure_to_nicotine_containing_products___urine

Basic Attributes

Class: PANEL.PHENX
Type: Clinical
First Released: Version 2.36
Last Updated: Version 2.81 (MIN)
Change Reason: Release 2.81: Status: Changing concept status from Trial to Discouraged upon recommendation from RTI; concept is deprecated in PhenX toolkit; Previous Releases: Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type: Panel

Member of these Panels

LOINC	Long Common Name
62611-9	PhenX domain - Respiratory

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	PhenX - αναπνευστικό - δοκιμασία ούρων για έκθεση σε καπνό τσιγάρου πρωτόκολλο 091701:-:Pt:^Ασθενής:-:PhenX Synonyms: - PANEL.PHENX PHENX PhenX - αναπνευστικό - δοκιμασία ούρων για έκθεση σε καπνό τσιγάρου πρωτόκολλο 091701 Pt Ασθενής
es-MX	Spanish (Mexico)	PhenX - respiratorio - análisis de orina para el protocolo de exposición al humo de tabaco 091701:-:Punto temporal:^ Paciente:-:PhenX
it-IT	Italian (Italy)	PhenX - respiratorio - esame delle urine per l'esposizione al fumo di tabacco, protocollo:-:Pt:^Paziente:-:PhenX Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio)
ru-RU	Russian (Russian Federation)	PhenX - дыхание - мочи анализ для подтверждения табакокурения протокол:-:ТчкВрм:^Пациент:-:PhenX Synonyms: Точка во времени;Момент
zh-CN	Chinese (China)	PhenX - 呼吸系统 - 烟草烟雾暴露尿液检测方案 091701:-:时间点:^患者:-:PhenX Synonyms: Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Consensus measures for Phenotypes and eXposures;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 PhenX - 呼吸系统 - 烟草烟雾暴露（接触）尿液检测（分析）方案 091701;Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标医嘱套餐医嘱套餐类医嘱套餐组医嘱组医嘱组.PhenX;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.PhenX;Consensus measures for Phenotypes and eXposures;PhenX;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标;PhenX 医嘱组医嘱组合医嘱组合类医嘱组套医嘱组套类医嘱组类医疗服务对象;客户;病人;病患;病号;超系统 - 病人多重;多重型;多重标尺类型;多重精度类型套餐套餐医嘱套餐医嘱组套餐医嘱组类实验室医嘱套餐实验室医嘱套餐类实验室医嘱组实验室医嘱组合类实验室医嘱组套实验室医嘱组套类实验室套餐医嘱组实验室套餐医嘱组类实验室检验项目医嘱组合类实验室检验项目组合类时刻;随机;随意;瞬间曝光检验医嘱组合类检验项目医嘱组合类检验项目组合类组组合组合医嘱组合类组套辐照

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62641-6
Questionnaire definition: https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/62641-6

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.