Version 2.69

62805-7PhenX - fasting serum insulin protocol 141301Trial

Status Information


Term Description

This protocol provides instructions for drawing, processing and storing blood according to the National Health and Nutrition Examination Survey (NHANES) methods. As there are no standard assays for insulin, the protocol also provides basic guidelines to aid comparability among different studies. Although all three are valuable standalone measures and all should be collected if resources are available, the Diabetes Working Group recommends that investigators prioritize Insulin 1st, C-peptide 2nd and Proinsulin 3rd. This is because results from the Insulin bioassay can be combined with results from Fasting Plasma Glucose bioassay to derive the homeostatic model assessment (HOMA) of insulin resistance and pancreatic beta cell function. The Diabetes Working Group notes that while it is not the preferred method, the Serum Insulin Assay can be performed on individuals who have not met the fasting requirements. The Diabetes Working Group notes that there are also protocols to collect samples for Serum Insulin concentrations at 0, 30, 60, 90 and 120 minutes and that this could be done at the same time as the Oral Glucose Tolerance Test. Such protocols would give extra specificity and information but would increase the burden on both the participant and investigator.
Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
62805-7 PhenX - fasting serum insulin protocol 141301
Indent66164-5 Did you eat or drink anything other than plain water after 11:30 last night?
Indent66165-2 When did you last eat or drink anything other than plain water?
Indent66166-0 Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
Indent66167-8 If Yes, record date
Indent66168-6 Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
Indent66169-4 If Yes, record date
Indent66170-2 Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
Indent66171-0 If Yes, record date
Indent66172-8 Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
Indent66173-6 If Yes, record date
Indent66182-7 Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
Indent66183-5 If Yes, record date
Indent66177-7 Do you have hemophilia?
Indent66178-5 Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66505-9 Exclusion Criteria
Indent66180-1 Was blood drawn?
Indent66181-9 Was full sample obtained?
Indent8251-1 Service comment
Indent8251-1 Service comment
Indent66200-7 Repeatability of the assay {ratio}
Indent66201-5 Coefficient of variation for the assay {CV}
Indent66202-3 Was the participant fasting?

Fully-Specified Name

PhenX - fasting serum insulin protocol 141301

Additional Names

Short Name
Fasting serum insulin proto

Survey Question


Basic Attributes

First Released
Version 2.36
Last Updated
Version 2.66
Change Reason
Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type

Reference Information

Type Source Reference
Article Consensus measures for Phenotypes and Exposures American Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61.
Article Consensus measures for Phenotypes and Exposures Marques, RG, Fontaine, MJ, & Rogers, J. (2004). C-peptide - much more than a byproduct of insulin biosynthesis. Pancreas, 29(3), 231-238.

Member of these Panels

LOINC Long Common Name
62787-7 PhenX domain - Diabetes

Language Variants Get Info

zh-CNChinese (China)
PhenX - 空腹血清胰岛素方案 141301:-:时间点:^患者:-:PhenX
it-ITItalian (Italy)
PhenX - insulina nel siero a digiuno, protocollo:-:Pt:^Paziente:-:PhenX
ru-RURussian (Russian Federation)
PhenX - голодание сывороточный инсулин протокол:-:ТчкВрм:^Пациент:-:PhenX

LOINC FHIR® API Example - CodeSystem Request Get Info