6297-6
Complement C1q Ag [Units/volume] in Serum
Active
Part Descriptions
LP16352-4 Complement C1q
A subcomponent of complement C1, composed of six copies of three polypeptide chains (A, B, and C), each encoded by a separate gene (C1QA; C1QB; C1QC). This complex is arranged in nine subunits (six disulfide-linked dimers of A and B, and three disulfide-linked homodimers of C). C1q has binding sites for antibodies (the heavy chain of IMMUNOGLOBULIN G or IMMUNOGLOBULIN M). The interaction of C1q and immunoglobulin activates the two proenzymes COMPLEMENT C1R and COMPLEMENT C1S, thus initiating the cascade of COMPLEMENT ACTIVATION via the CLASSICAL COMPLEMENT PATHWAY.
Source: National Library of Medicine, MeSH 2006
LP16352-4 Complement C1q
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement (C1) is composed of 3 subunits: C1q, C1r, and C1s. Complement C1q initiates the complement pathway by binding to immunoglobulins. Absent or decreased levels of Complement C1q are seen in patients with acquired angioedema, systemic lupus erythematosus (SLE), polymyositis, and other immune complex diseases. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Complement C1q Ag
- Property
- ACnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- C1q Ag Ser-aCnc
- Display Name
- Complement C1q Ag Qn (S)
- Consumer Name Alpha Get Info
- Complement C1q antigen, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 1.0e
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 11416
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | antígeno del componente C1Q del complemento [Ag]: |
es-ES | Spanish (Spain) | Complemento C1q Antígeno: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Complemento C1q Ag: |
et-EE | Estonian (Estonia) | Komplemendi komponent C1q antigeen: Synonyms: Juhuslik Kvantitatiivne Seerum |
fr-CA | French (Canada) | Complément C1q, Ag: |
fr-FR | French (France) | Complément C1q antigène: |
fr-BE | French (Belgium) | Complément C1q Ag: Synonyms: Antigène |
it-IT | Italian (Italy) | Complemento C1q, Ag: Synonyms: Concentrazione Arbitraria Ematologia (coagulazione) conta differenziale Punto nel tempo (episodio) Siero |
ko-KR | Korean (Korea, Republic Of) | 도움체 C1q 항원: |
nl-NL | Dutch (Netherlands) | complement C1q Ag: Synonyms: antigeen |
pt-BR | Portuguese (Brazil) | Complemento C1q Ag: Synonyms: Complement c1q binding; |
ru-RU | Russian (Russian Federation) | Комплемент C1q Аг: Synonyms: Количественный Произвольная концентрация Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Kompleman C1q Ag: Synonyms: Antijen |
zh-CN | Chinese (China) | 补体 C1q 抗原: Synonyms: Ag 任意型浓度(单位体积); |
Example Units
Unit | Source |
---|---|
units | eCHN |
[arb'U]/mL | Example UCUM Units |
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