Version 2.80

Part Descriptions

LP14679-2   Keratin
A class of fibrous proteins or scleroproteins important both as structural proteins and as keys to the study of protein conformation. The family represents the principal constituent of epidermis, hair, nails, horny tissues, and the organic matrix of tooth enamel. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms an alpha-helix, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. Source: National Library of Medicine, MeSH 2006

LP14679-2   Keratin
Keratin refers to a family of fibrous structural proteins. Keratin is the key of structural material making up the outer layer of human skin. It is also the key structural component of hair and nails.

Some infectious fungi, such as those that cause athlete's foot and ringworm (i.e. the dermatophytes), or Batrachochytrium dendrobatidis (Chytrid fungus), feed on keratin.

Diseases caused by mutations in the keratin genes include Epidermolysis bullosa simplex, Ichthyosis bullosa of Siemens, Epidermolytic hyperkeratosis, Steatocystoma multiplex, Keratosis pharyngis, Rhabdoid cell formation in Large cell lung carcinoma with rhabdoid phenotype.

Furthermore, keratin expression is helpful in determining epithelial origin in anaplastic cancers. Tumors that express keratin include carcinomas, thymomas, sarcomas and trophoblastic neoplasms. Furthermore, the precise expression pattern of keratin subtypes allows prediction of the origin of the primary tumor when assessing metastases. For example, hepatocellular carcinomas typically expresse K8 and K18, and cholangiocarcinomas express K7, K8 and K18, while metastases of colorectal carcinomas express K20, but not K7 Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

Fully-Specified Name

Component
Keratin Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Long Common Name
Keratin Ab [Presence] in Serum by Immunofluorescence
Short Name
Keratin Ab Ser Ql IF
Display Name
Keratin Ab IF Ql (S)
Consumer Name Alpha Get Info
Keratin antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κερατίνη Αντίσωμα:PrThr:Pt:Ορός:Ord:Ανοσοφθορισμός
Synonyms: PrThr Κερατίνη
es-ES Spanish (Spain) Queratina Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Queratina Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Keratiin antikehad:PrThr:Pt:S:Ord:IF
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Kératine, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-FR French (France) Kératine anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Kératine Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
Synonyms: Anticorps
it-IT Italian (Italy) Cheratina Ab:PrThr:Pt:Siero:Ord:IF
Synonyms: anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) keratine As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
ru-RU Russian (Russian Federation) Кератин Ат:PrThr:ТчкВрм:Сыв:Пор:ИФ
Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Keratin Ab:MevcEşik:Zmlı:Ser:Srl:IF
Synonyms: İmmünflorerans Mevcut
zh-CN Chinese (China) 角蛋白 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 表皮蛋白和纤维蛋白;角朊;角质;革质朊 角朊 Ab 角朊抗体 角蛋白 Ab 角质 Ab 角质抗体 革质朊 Ab 革质朊抗体

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63268-7