64133-2
PHENobarbital/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP14729-5 PHENobarbital
Phenobarbital is an antiepileptic drug first introduced for clinical use in 1912. It is still used to treat most seizures except for absence seizure types. The CYP2C19 enzyme metabolizes phenobarbital to p-hydroxyphenobarbital which is then excreted as glucuronide. Phenobarbital induces secretion of liver enzymes which can impact the efficacy of drugs administered at the same time. The most common side effect of phenobarbital in adults with blood levels greater than 40 mg/L is sedation. Phenobarbital is an active metabolite of primidone and so must also be monitored in patients on primidone.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns)
Source: Regenstrief LOINC
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Creatinine
Fully-Specified Name
- Component
- PHENobarbital/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- PHENobarbital/Creatinine [Mass Ratio] in Urine
- Short Name
- Phenobarb/Creat Ur
- Display Name
- PHENobarbital/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- PHENobarbital/Creatinine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4711
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Φαινοβαρβιτάλη/Κρεατινίνη: Synonyms: MRto Κρεατινίνη Φαινοβαρβιτάλη |
es-ES | Spanish (Spain) | Fenobarbital/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | FENobarbital / Creatinina: |
et-EE | Estonian (Estonia) | Fenobarbitaal/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-CA | French (Canada) | Phénobarbital/Créatinine: |
fr-FR | French (France) | Phénobarbital/créatinine: |
fr-BE | French (Belgium) | Phénobarbital/Créatinine: Synonyms: Rapport de masse |
it-IT | Italian (Italy) | Fenobarbital/Creatinina: Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa |
nl-NL | Dutch (Netherlands) | fenobarbital/creatinine: Synonyms: kreatinine |
ru-RU | Russian (Russian Federation) | Фенобарбитал/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
tr-TR | Turkish (Turkey) | Fenobarbital/Kreatinin: |
zh-CN | Chinese (China) | 苯巴比妥/肌酐: Synonyms: C12H12N2O3; |
Example Units
Unit | Source |
---|---|
ng/mg{creat} | Example UCUM Units |
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LOINC Copyright
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