6765-2

17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma

Active

Part Descriptions

LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, 17-hydroxypregnenolone (Wikipedia)

LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: 17-Hydroxypregnenolone:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: 17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma
Short Name: 17OH-Preg SerPl-mCnc
Display Name: 17-Hydroxypregnenolone [Mass/Vol]
Consumer Name Alpha Get Info: 17-Hydroxypregnenolone, Blood

Part Model Get Info

Component
17-Hydroxypregnenolone
LP17184-0
- Analyte
  17-Hydroxypregnenolone
  LP17184-0
  - Component Numerator
    17-Hydroxypregnenolone
    LP17184-0
    - Component Numerator Core
      17-Hydroxypregnenolone
      LP17184-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 1.0h(2)
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 4115

Member of these Panels

LOINC	Long Common Name
94303-5	Pregnenolone and 17-Hydroxypregnenolone panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group	Group Name
LG41941-2	17-Hydroxypregnenolone\|Pt\|Ser/Plas

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	17 هيدروكسي بريغنينولون ( بتقنية الكتلة / الحجم ) في البول المصل أو البلازما
cs-CZ	Czech (Czechia)	17-hydroxypregnenolon:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	17-υδροξυπρογνενολόνη:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: 17-υδροξυπρογνενολόνη CHEM MCnc Pt Qn Ορός Ορός/Πλάσμα Πλάσμα
es-AR	Spanish (Argentina)	17-hidroxipregnenolona:concentración de masa:punto en el tiempo:suero:cuantitativo:
es-ES	Spanish (Spain)	17-Hidroxipregnenolona:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	17-hidroxipregnenolona:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	17-hüdroksüpregnenoloon:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	17-hydroxyprégnénolone:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	17-hydroxyprégnénolone:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	17-hydroxyprégnénolone:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	17-Idrossipregnenolone:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	17-하이드록시프레그네놀론:질량농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	17-hydroxypregnenolon:massa/volume:moment:serum of plasma:kwantitatief:
pl-PL	Polish (Poland)	17-Hydroksypregnenolon:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR	Portuguese (Brazil)	17-hidroxipregnenolona:MCnc:Pt:Sor/Plas:Qn: Synonyms: ; 17OH-Preg; 17 hydroxy pregnenolone; 17-alpha-Hydroxypregnenolone; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	17-Гидроксипрегненолон:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	17-Hidroksipregnenolon:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	17-羟基孕烯醇酮:质量浓度:时间点:血清/血浆:定量型: Synonyms: 17-Alpha-羟基娠烯醇酮;17-Alpha-羟基孕 5 烯 3β醇 20 酮;17-Alpha-羟基孕烯诺龙;17-Alpha-羟基孕烯醇酮;17-Alpha-羟基孕甾烯醇酮;17OH-Preg;17-α-羟基娠烯醇酮;17-α-羟基孕 5 烯 3β醇 20 酮;17-α-羟基孕烯诺龙;17-α-羟基孕烯醇酮;17-α-羟基孕甾烯醇酮;17-羟基娠烯醇酮;17-羟基孕 5 烯 3β醇 20 酮;17-羟基孕烯诺龙;17-羟基孕甾烯醇酮;17-羟娠烯醇酮;17-羟孕 5 烯 3β醇 20 酮化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 血清或血浆

Example Units

Unit	Source
ng/dL	Example UCUM Units
ng/dL	REGENSTRIEF
ng/dL	eCHN

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.