6788-4

Kappa light chains/Lambda light chains [Mass Ratio] in Serum by Immunoassay

Active

Part Description

LP15030-7 Immunoglobulin light chains.kappa
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda:MRto:Pt:Ser:Qn:IA
Long Common Name: Kappa light chains/Lambda light chains [Mass Ratio] in Serum by Immunoassay
Short Name: Kappa LC/Lambda Ser IA
Display Name: Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda IA (S) [Mass ratio]
Consumer Name Alpha Get Info: Immunoglobulin light chains.kappa/Immunoglobulin Light Chains.lambda, Blood

Part Model Get Info

Component
Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda
LP307486-3
- Analyte
  Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda
  LP307486-3
  - Component Numerator
    Immunoglobulin light chains.kappa
    LP15030-7
    - Component Numerator Core
      Immunoglobulin light chains.kappa
      LP15030-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Immunoglobulin light chains.lambda
    LP32074-4
    - Component Denominator Core
      Immunoglobulin light chains.lambda
      LP32074-4
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MRto
LP6834-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 1.0h(2)
Last Updated: Version 2.73 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016. Changed the LCN from 'Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda' to ' Kappa light chains/Lambda light chains' for readability.
Order vs. Observation: Observation
Common Test Rank Get Info: 3908

Member of these Panels

LOINC	Long Common Name
44793-8	Immunoglobulin light chains panel [Mass/volume] - Serum

Member of these Groups Get Info

LOINC Group	Group Name
LG3250-0	Immunoglobulin light chains.kappa/Immunoglobulin light chains.lambda\|MRto\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Ig lehké řetězce.kappa/Ig lehké řetězce.lambda:Hmotnostní poměr:Časový bod:Sérum:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	Ελαφριές αλυσίδες ανοσοσφαιρίνης.κάπα/Ελαφριές αλυσίδες ανοσοσφαιρίνης.λάμδα:MRto:Pt:Ορός:Qn:IA Synonyms: CHEM IA MRto Pt Qn Ελαφρές αλυσίδες ανοσοσφαιρίνης Ελαφριές αλυσίδες ανοσοσφαιρίνης.κάπα Ελαφριές αλυσίδες ανοσοσφαιρίνης.λάμδα Ορός
es-AR	Spanish (Argentina)	cadenas livianas de inmunoglobulina.kappa/cadenas livianas de inmunoglobulina.lambda:relación de concentración de masa:punto en el tiempo:suero:cuantitativo:enzimoinmunoanálisis
es-ES	Spanish (Spain)	Cadenas ligeras de las inmunoglobulinas.kappa/Cadenas ligeras de inmunoglobulina (cadenas lambda):Relacion de Masa:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cadenas ligeras de inmunoglobulina kappa / Cadenas ligeras de inmunoglobulina lambda:Relación de masa:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Immuunoglobuliini kerged ahelad.kapa/immuunoglobuliini kerged ahelad.lambda:MRto:Pt:S:Qn:IA Synonyms: Immuunglobuliinide kerged kapaahelad Immuunglobuliinide kerged lambdaahelad Juhuslik Kvantitatiivne Seerum
fr-CA	French (Canada)	Chaînes légères d'immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda:Ratio de masse:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR	French (France)	Immunoglobuline chaines légères kappa/immunoglobuline chaines légères lambda:Masse ratio:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Chaînes légères immunoglobulines.kappa/Chaînes légères d'immunoglobulines.lambda:Ratio de masse:Temps ponctuel:Sérum:Quantitatif:IA Synonyms: LC LC. Kappa LC. Lambda LC.Lambda Rapport de masse
it-IT	Italian (Italy)	Immunoglobuline, catene leggere.kappa/Immunoglobuline, catene leggere.lambda:MRto:Pt:Siero:Qn:IA Synonyms: Catene leggere delle immunoglobuline Catene leggere kappa delle immunoglobuline Catene leggere lambda delle immunoglobuline Chimica Immunoassay Punto nel tempo (episodio) Rapporto di Massa Siero
ko-KR	Korean (Korea, Republic Of)	카파면역글로불린 경쇄/람다면역글로불린 경쇄:질량농도비:검사시점:혈청:정량:효소면역측정법
nl-NL	Dutch (Netherlands)	immunoglobuline lichte ketens.kappa/lichte-keten immunoglobuline.lambda:massaverhouding:moment:serum:kwantitatief:immunoassay Synonyms: IA immunoglobuline lichte ketens.lambda
pl-PL	Polish (Poland)	Łańcuchy lekkie immunoglobuliny.kappa/łańcuchy lekkie lambda immunoglobuliny:współczynnik masowy:punkt w czasie:surowica:ilościowy:metoda immunologiczna Synonyms: Łańcuchy immunoglobulin lekkie kappa / łańcuchy immunoglobulin lekkie lambda Łańcuchy lekkie immunoglobulin Łańcuchy lekkie kappa immunoglobuliny Łańcuchy lekkie lambda immunoglobuliny
pt-BR	Portuguese (Brazil)	Imunoglobulinas cadeias leves.kappa/Imunoglobulinas cadeias leves.lambda:MCrto:Pt:Soro:Qn:Imunoensaio Synonyms: ; Kappa LC; Lambda LC; BJ Protein; BJP; Bence Jones protein; Kappa/Lambda; mRto; Mass concentration ratio; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Chemistry
ru-RU	Russian (Russian Federation)	Иммуноглобулин легкие цепи.каппа/Иммуноглобулин легкие цепи.лямбда:МассОтн:ТчкВрм:Сыв:Колич:IA Synonyms: Количественный Масс отношение Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	İmmünglobulin hafif zincirler.kappa/İmmünglobulin hafif zincirler.lambda:KütlOr:Zmlı:Ser:Kant:İA Synonyms: İmmünölçüm, immünoassay
zh-CN	Chinese (China)	免疫球蛋白轻链.Kappa 型/免疫球蛋白轻链.Lambda:质量比率:时间点:血清:定量型:免疫测定法 Synonyms: Bence Jones 氏蛋白;Bence Jones 蛋白;BJ 蛋白;B-J 蛋白;BJP;本周氏蛋白;本-周氏蛋白;本周氏蛋白（Bence Jones protein，BJ Protein，BJP）;本周蛋白;本-周蛋白 Ig Kappa LC;Kappa 型免疫球蛋白轻链;Kappa 型轻链;Kappa 轻链;κ型免疫球蛋白轻链;κ型轻链;κ轻链;免疫球蛋白轻链.Kappa;免疫球蛋白轻链.κ型;轻链.Kappa;轻链.Kappa 型;轻链.κ;轻链.κ型 Lambda LC;Lambda 型免疫球蛋白轻链;Lambda 型轻链;Lambda 轻链;λ型免疫球蛋白轻链;λ型轻链;λ轻链;免疫球蛋白轻链.Lambda;免疫球蛋白轻链.λ型;轻链.Lambda;轻链.Lambda 型;轻链.λ;轻链.λ型 Lambda 轻链;免疫球蛋白轻链.λ;λ轻链丙种球蛋白免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白（Immunoglobulin，Ig）免疫球蛋白类化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间来自于同一体系的两种分析物的质量之比;质量比链

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.