Version 2.78

Term Description

Test is a rapid enzyme immunoassay used as a diagnostic aid for the detection and differentiation of HIV-1 and HIV-2 antibodies in serum or plasma. This code is based on, but not limited to, BIO-RAD's Multispot HIV-1/HIV-2 Rapid Test, which was approved in June of 2012 by the FDA for distinguishing HIV-1 from HIV-2 and is being considered as a replacement for Immune blot for the confirmation of positive HIV EIA tests by routine methods. It takes approximately 15 minutes to complete.
Source: Regenstrief LOINC

Part Description

LP36650-7   HIV 1 & 2
Human immunodeficiency virus (HIV) is categorized into two types, HIV-1 and HIV-2. Worldwide, most HIV infections are HIV-1, whereas HIV-2 largely has been confined to persons in or from West Africa (1,2). HIV-1 and HIV-2 have the same routes of transmission, and both can cause acquired immunodeficiency syndrome (AIDS) (3); however, HIV-2 infections should be differentiated from HIV-1 infections because they are less likely to cause AIDS and their clinical management differs (4,5). CDC's current surveillance case definition for HIV infection applies to both variants of HIV (6) but lacks criteria for differentiating between HIV-1 and HIV-2.

To enumerate and describe HIV-2 cases reported in the United States, a working case definition was developed. During 1988 through June 2010, a total of 242 HIV-2 cases were reported to CDC. Of these, 166 met the working definition. These HIV-2 cases were concentrated in the Northeast (66%, including 46% in New York City) and occurred primarily among persons born in West Africa (81%). Ninety-seven of the HIV-2 cases also had a positive HIV-1 immunoblot antibody test result (e.g., Western blot). Immunoblot antibody tests currently used to confirm HIV reactive screening tests do not contain reagents specific to HIV-2 and thus are not reliable for identification of HIV-2 infections (7). Additional testing specific to HIV-2 should be considered if HIV-1 test results are atypical or inconsistent with clinical findings, especially for persons from West Africa. If an HIV case is reported to the health department but subsequently identified as HIV-2, health-care providers should update the case report to reflect the correct type. As of June 2012, the Bio-Rad Multispot HIV-1/HIV-2 Rapid Test is FDA approved for distinguishing HIV1 from HIV2. Source: Centers for Disease Control and Prevention, LV Torian, et al. HIV-2 Infection Surveillance -- United States, 1987-2009. Morbidity and Mortality Weekly Report 60(29);985-988. July 29, 2011.

Reference Information

Type Source Reference
Package Insert BIO-RAD Example package insert. This LOINC code is not constrained to this specific product. BIO-RAD Multispot HIV-1/HIV-2 Rapid Test

Fully-Specified Name

Component
HIV 1 & 2 Ab
Property
Prid
Time
Pt
System
Ser/Plas
Scale
Nom
Method
IA.rapid

Additional Names

Short Name
HIV 1 & 2 Ab SerPl IA.rapid
Display Name
HIV 1 and 2 Ab IA.rapid Nom
Consumer Name Alpha Get Info
HIV 1 and 2 antibody, Blood

Example Answer List: LL1996-9

Source: BIO-RAD
Answer Code Score Answer ID
NonreactiveCopyright http://snomed.info/sct ID:131194007 Non-reactive (qualifier value) LA15256-3
HIV-1 reactive LA18330-3
HIV-2 reactive LA18331-1
HIV Reactive (Undifferentiated) LA18332-9
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
16196

Member of these Panels

LOINC Long Common Name
75622-1 HIV 1 and 2 tests - Meaningful Use set

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) HIV 1 y 2 Anticuerpos:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:IA.rapid
es-MX Spanish (Mexico) VIH 1 y 2 Ab:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Inmunoensayo rápido
fr-CA French (Canada) VIH 1 & 2, Ac:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:IA.rapide
fr-FR French (France) VIH-1 et VIH-2 Ac:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:Immunoanalyse rapide
fr-BE French (Belgium) VIH 1 & 2 Ac:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:IA.rapid
Synonyms: Anticorps HIV HIV 1 HIV 1&2 HIV 1+2
it-IT Italian (Italy) HIV 1 & 2 Ab:Prid:Pt:Siero/Plasma:Nom:IA.rapido
Synonyms: anticorpo Immunoassay Immunoassay rapido Microbiologia Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) HIV 1 & 2 As:identificator:moment:serum of plasma:nominaal:immunoassay.sneltest
Synonyms: antistof; antilichaam IA IA.rapid
pl-PL Polish (Poland) HIV 1 i 2 Ab:wykrycie lub identyfikacja:punkt w czasie:surowica lub osocze:cecha:szybka metoda immunologiczna
Synonyms: Ludzki wirus niedoboru odporności typu 1 Ludzki wirus niedoboru odporności typu 1 i 2 Ludzki wirus niedoboru odporności typu 1+2 Przeciwciała do HIV 1 i 2 Przeciwciała do HIV 1+2
ru-RU Russian (Russian Federation) HIV 1 & 2 Ат:ПрИд:ТчкВрм:Сыв/Плаз:Ном:IA.rapid
Synonyms: Антитело ВИЧ ВИЧ 1 ВИЧ 1 и 2 ВИЧ 1+2 Номинальный;Именной Плазма Присутствие или Идентификация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) HIV 1 ve 2 Ab:MevcKimlik:Zmlı:Ser/Plaz:Snf:İA.hızlı
Synonyms: Ak İmmünölçüm, immünoassay
zh-CN Chinese (China) HIV 1 型 与 2 型 抗体:存在与否或特征标识:时间点:血清/血浆:名义型:免疫测定法.快速
Synonyms: Ⅰ Ⅱ Ab;自身抗体 AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV 1 & 2 Ab HIV 1+2 Ab HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I II 人类免疫缺陷病毒 1 & 2 型 Ab 人类免疫缺陷病毒 1 & 2 型抗体 人类免疫缺陷病毒 1 与 2 型 Ab 人类免疫缺陷病毒 1 与 2 型;HIV（人类免疫缺陷病毒、人免疫缺陷病毒、艾滋病病毒） 1 型（I 型） 与 2 型（II 型） 人类免疫缺陷病毒 1 与 2 型抗体 人类免疫缺陷病毒 1+2 型 Ab 人类免疫缺陷病毒 1+2 型;HIV 1+2 型（人类免疫缺陷病毒 1+2 型、人类免疫缺陷病毒 I+II 型、人免疫缺陷病毒 1+2 型、人免疫缺陷病毒 I+II 型、HIV I+II、HIV I+II 型、艾滋病病毒 I+II 型） 人类免疫缺陷病毒 1+2 型抗体 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 快速免疫测定;快速免疫测定法;快速免疫分析法;快速免疫检定法;快速免疫检定;快速免疫试验;酶免疫测定法.快速;快速酶免疫测定法;快速酶免疫测定;快速酶免疫分析法;快速酶免疫检定法;快速酶免疫检定;快速酶免疫试验 时刻;随机;随意;瞬间 血清或血浆

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