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Part Description

LP145978-5   CCR2 gene.p.Val64Ile
The chemokine (C-C motif) receptor 2 (CCR2) gene is located on chromosome 3p21. A single nucleotide polymorphism (SNP) of G to A at position 190 changes amino acid valine (GTC) to isoleucine (ATC) within codon 64 (CCR2-V64I). This change is associated with a reduced risk of progression to AIDS in HIV-infected individuals, renal transplant rejection, multiple sclerosis and development of breast cancer. The CCR2-V64I polymorphism may also reduce the risk of cervical cancer in some women, but study findings are conflicting. PMID: 20537184 Source: Regenstrief LOINC, PMID: 20537184

LOINC Names Get Info

Fully-Specified Name
CCR2 gene.p.Val64Ile:PrThr:Pt:Bld/Tiss:Ord:Molgen
Long Common Name
CCR2 gene p.Val64Ile [Presence] in Blood or Tissue by Molecular genetics method
Short Name
CCR2 p.V64I Bld/T Ql
Display Name
CCR2 gene p.Val64Ile Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
CCR2 gene p.Val64Ile, Blood or tissue specimen

Part Model Get Info

  • Component
    CCR2 gene.p.Val64Ile
    LP145978-5
    • Analyte
      CCR2 gene.p.Val64Ile
      LP145978-5
      • Component Numerator
        CCR2 gene.p.Val64Ile
        LP145978-5
        • Component Numerator Core
          CCR2 gene.p.Val64Ile
          LP145978-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Molgen
    LP6404-0

Example Answer List: LL2014-0

Source: Estonian Society of Laboratory Medicine
AnswerCodeScoreAnswer ID
Wild typeLA9658-1
HeterozygousLA6706-1
HomozygousLA6705-3

Basic Attributes

Class
MOLPATH.MUT
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.68 (MIN)
Change Reason
Property has been changed from Arb (arbitrary) to Pr (presence) to reflect our current model for Ordinal terms where the results are based on the presence or absence of a mutation or variant. Scale has been changed from Nom to Ord since results (e.g. present/absent or wildtype, heterozgous, homozygous) are ordinal. Changed Component name to align with the current HGVS recommendations to use the three letter codes for amnio acids. In the shortname, we kept the single letter codes.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen CCR2 p.Val64Ile:Přítomnost nebo práh:Časový bod:Krev/tkáň:Ordinální:Molekulární genetika
el-GRGreek (Greece)Γονίδιο CCR2 p.Val64Ile:PrThr:Pt:Αίμα/Ιστός:Ord:Μοριακή γενετική
Synonyms: MOLPATH MOLPATH.MUT Ord P PrThr Pt Αίμα Αίμα/Ιστός Γονίδιο Γονίδιο CCR2 p.Val64Ile Ιστός Μοριακή γενετική
es-ESSpanish (Spain)Gen CCR2 .p.V64I:PrThr:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MXSpanish (Mexico)Gen CCR2 p. Val64Ile:Presencia o umbral:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FRFrench (France)CCR2 gène p.Val64Ile:Présence/Seuil:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-ITItalian (Italy)CCR2, gene.p.Val64Ile:PrThr:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Gene CCR2 p.Val64Ile Genetica molecolare Mutazione genica Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NLDutch (Netherlands)CCR2-gen.p.V64I:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: CCR2 gen.p.V64I molgen
pl-PLPolish (Poland)CCR2 gen.p.Val64Ile:granica wykrywalności:punkt w czasie:krew lub tkanka:uporządkowany:genetyka molekularna
Synonyms: diagnostyka molekularna Gen CCR2 p.Val64Ile
ru-RURussian (Russian Federation)CCR2 ген.p.V64I:PrThr:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Ткань и мазки Точка во времени;Момент
tr-TRTurkish (Turkey)CCR2 geni.p.V64I:MevcEşik:Zmlı:Kan/Dk:Srl:Molgen
Synonyms: Mevcut
zh-CNChinese (China)CCR2 基因.p.V64I:存在情况或阈值:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: CCR2-V64I基因;CCR2-64I P 型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=70246-4