Version 2.78

Term Description

This code describes molecular detection of Entamoeba histolytica/dispar complex (E. histolytica, E. dispar, E. nuttalli, and E ecuadoriensis) DNA by RT-PCR. It targets a sequence of the DNA coding for the 15S ribosomal RNA that is common to these four species. So a positive result indicates whether any one of these species is present without specifying which one. In the submitter's laboratory, it is used only on human specimens, mostly stool but pus and tissue as well. E. dispar is a commensal in the human digestive tract, and E. histolytica is the only one thought to be pathogenic in humans. The other two species are found in animals and not thought to inhabit the human gut. A positive can be followed up in the submitter's lab by specific identification of the species using DNA sequencing (see LOINC 70294-4).

Additional species that have been found in the gut include Entamoeba moshkovskii, Entamoeba poleki, Entamoeba coli, and Entamoeba hartmanni. E. histolytica, E. dispar, and E.moshkovskii are morphologically identical but are different biochemically and genetically.
Source: Regenstrief LOINC

Part Descriptions

LP146105-4   Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli
Entamoeba histolytica and Entamoeba dispar are a complex of two different but morphologically identical species. E. dispar is non-invasive commensal in the intestine of humans. E. histolytica is an invasive species assoicated with cell and tissue damage. Source: Regenstrief LOINC

LP21259-4   Entamoeba
A genus of ameboid protozoa characterized by the presence of beaded chromatin on the inner surface of the nuclear membrane. Its organisms are parasitic in invertebrates and vertebrates, including humans. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli DNA
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
E his+dis+ecua+nutt DNA Spec Ql NAA+prb
Display Name
E. histolytica+E. dispar+E. ecuadoriensis+E. nuttalli DNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info
Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli, Specimen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.69
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli ADN:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Entamoeba histolytica + Entamoeba dispar + Entamoeba ecuadoriensis + ADN de Entamoeba nuttalli:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli ADN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli DNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli DNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli DNA:Limiar:Pt:XXX:Ord:Sonda com limite de detecção da amplificação de alvo
ru-RU Russian (Russian Federation) Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli ДНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Entamoeba histolytica+Entamoeba dispar+Entamoeba ecuadoriensis+Entamoeba nuttalli DNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 溶组织内阿米巴+迪斯帕内阿米巴+厄瓜多尔内阿米巴+纳氏内阿米巴 DNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向
Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 内变形虫 内变形虫属 内阿米巴属 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸(Deoxyribonucleic acid,DNA) 变形虫 变形虫属 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 扩增型 扩增性 时刻;随机;随意;瞬间 溶组织内阿米巴(溶组织肠阿米巴)+迪斯帕肠阿米巴+厄瓜多尔内阿米巴+纳氏内阿米巴;变形虫病;阿米巴病 溶组织肠阿米巴;变形虫病;阿米巴病 经过扩增的 肠阿米巴属 脱氧核糖核酸探针 迪斯帕肠阿米巴;非侵入性阿米巴;非侵入性阿米巴原虫 阿米巴

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=70293-6