LOINC
Version 2.67

70568-1Plasmodium knowlesi DNA [Presence] in Blood by NAA with probe detectionActive

Part Descriptions

LP146623-6   Plasmodium knowlesi
Plasmodium knowlesi is a primate malaria parasite commonly found in Southeast Asia. It causes malaria in long-tailed macaques (Macaca fascicularis), but it may also infect humans, either naturally or artificially.

Plasmodium knowlesi is the fifth major human malaria parasite. It may cause severe malaria as indicated by its asexual erythrocytic cycle of about 24 hours, with an associated fever that typically occurs at the same frequency (i.e. the fever is quotidian). This is an emerging infection that was reported for the first time in humans in 1965. It accounts for up to 70% of malaria cases in certain areas in South East Asia where it is mostly found. This parasite is transmitted by the bite of an Anopheles mosquito. Plasmodium knowlesi has health, social and economic consequences for the regions affected by it.

Although the current infection rate with Plasmodium knowlesi is relatively low, one risk it presents is misdiagnosis with other forms of malarial parasites such as P. malariae especially when microscopy is used. P. knowlesi can only be accurately distinguished from P. malariae using PCR assay and/or molecular characterization.

Because P. knowlesi takes only 24 hours to complete its erythrocytic cycle, it can result in very high parasite density quickly and may be fatal in humans. For this reason early treatment is advised. It responds well to treatment with chloroquine and primaquine. but if parasite counts are high and patients are severe, then infections should be treated as intensively as for severe falcipaum malaria. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP20149-8   Plasmodium
Malaria is a parasitic disease that is passed from one human to another by the bite of an infected Anopheles mosquito with one of four protozoan parasites: Plasmodium falciparum, vivax, malariae or ovale. The parasites enter the bloodstream and infect red blood cells where they multiply and infect more red blood cells. Symptoms usually occur 10 days to 4 weeks after infection and include anemia, high fevers, shaking chills, muscle pain, and nausea. Antimalarial agents used to treat malaria include Quinine, Quinidine, Mefloquine, Chloroquine, and Hydroxychloroquine. The effectiveness of the agents depends on which phase or phases of the Plasmodium life cycle is interrupted. In most cases, treatment outcome is expected to be good except in cases of a p. falciparum infection. Adverse effects from antimalaria medications include vomiting, diarrhea, headaches, cardiac arrhythmias, EKG abnormalities, deafness, damage to liver and kidney and muscle weakness. Source: NMS labs

Fully-Specified Name

Component
Plasmodium knowlesi DNA
Property
PrThr
Time
Pt
System
Bld
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
P knowlesi DNA Bld Ql NAA+probe
Display Name
P. knowlesi DNA NAA+probe Ql (Bld)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.40
Last Updated
Version 2.63
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG41640-0 Plasmodium

Language Variants Get Info

zh-CNChinese (CHINA)
诺氏疟原虫 DNA:存在情况或阈值:时间点:全血:序数型:探针法.基因扩增.靶向
nl-NLDutch (NETHERLANDS)
Plasmodium knowlesi DNA:aanwezigheid:moment:bloed:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (FRANCE)
Plasmodium knowlesi ADN:Présence/Seuil:Ponctuel:Sang:Qualitatif:PCR amplification de cible
it-ITItalian (ITALY)
Plasmodium knowlesi , DNA:PrThr:Pt:Sangue:Ord:Sonda.amp.tar
pt-BRPortuguese (BRAZIL)
ru-RURussian (RUSSIAN FEDERATION)
Plasmodium knowlesi ДНК:PrThr:ТчкВрм:Кр:Пор:Проба.усил.миш
es-ESSpanish (SPAIN)
Plasmodium knowlesi ADN:PrThr:Punto temporal:Sangre:Ord:Sonda con amplificación dirigida
tr-TRTurkish (TURKEY)
Plasmodium knowlesi DNA:MevcEşik:Zmlı:Kan:Srl:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=70568-1