70970-9
Cryoglobulin [Presence] in Serum by Hypotonic dilution
Active
Term Description
Cryoglobulins are proteins in the blood that are soluble at 37 degrees Celsius but precipitate at lower temperatures. There are three classes of cryoglobulins that are differentiated by what type of protein precipitates. In type 1, the proteins involved are monoclonal immunoglobulins, usually IgM. Type 2 proteins include a mixture of monoclonal IgM and polyclonal IgG proteins. Type 3 may include polyclonal IgM and IgG cryoglobulins. In some cases, the proteins congeal rather than precipitate when observed in the laboratory. An additional process of hypotonically diluting the serum may be required in these instances in order to observe precipitation. PMID: 3787096
Source: Regenstrief LOINC
Part Description
LP15516-5 Cryoglobulin
Serum cryoglobulins are immunoglobulins that, in vitro, precipitate at temperatures below 37°C and redissolve on rewarming.Cryoglobulins can be transient and without clinical implications or they can be a marker of significant disease. Monoclonal cryoglobulins, which are IgG, IgM, or IgA, or monoclonal free light chains, are usually associated with haematological disorders. Mixed cryoglobulins, which contain polyclonal immunoglobulins with or without a monoclonal component, are found in many infectious and systemic disorders. There is a significant association between essential mixed cryoglobulinaemia and hepatitis C virus infection (> 90%). PMID: 11825916
Source: Regenstrief LOINC, PMID: 11825916
Fully-Specified Name
- Component
- Cryoglobulin
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Hypotonic dilution
Additional Names
- Short Name
- Cryoglob Ser Ql Hypotonic dilution
- Display Name
- Cryoglobulin Hypotonic dilution Ql (S)
- Consumer Name Alpha Get Info
- Cryoglobulin, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Crioglobulina: |
es-MX | Spanish (Mexico) | Crioglobulina: |
fr-FR | French (France) | Cryoglobulines: |
it-IT | Italian (Italy) | Crioglobulina: Synonyms: Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | cryoglobuline: |
pt-BR | Portuguese (Brazil) | Crioglobulina: |
tr-TR | Turkish (Turkey) | Kriyoglobulin: Synonyms: Mevcut |
zh-CN | Chinese (China) | 冷球蛋白: Synonyms: Cryo; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=70970-9
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright