71884-1
Carboxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Venous blood
Active
Term Description
Because of the confusion that occurs in countries that report results as both decimal fraction and percent, this property was created to represent decimal fractions that are reported without units.
Part Description
LP21418-6 Carboxyhemoglobin
Carboxyhemoglobin, a complex of hemoglobin and carbon monoxide, is a marker of exposure to inhaled carbon monoxide (CO). CO gas is produced from almost any fire as the result of incomplete combustion to CO2, and the normal individual will have about 1 or 2 % of their hemoglobin in the form of carboxyhemoglobin, and up to 5% depending on environmental circumstances. Smokers can have levels as high as 10% or even higher. Poisoning with CO generally results from improperly vented furnaces, automobile exhaust, and fires, with carboxyhemoglobin:hemoglobin ratios of 10-30% found in symptomatic individuals and 30-90% in fatalities. With a 230 fold greater affinity, inhaled CO avidly replaces oxygen at its hemoglobin binding site. In addition, replacing even one of the 4 sites of the hemoglobin tetramer with CO prevents dissociation of the remaining 3 oxygen moieties to tissue (known as left shift of O2 dissociation curve). As a result, hemoglobin remains red and skin color is rosy despite physiologic anoxia. Although measuring carboxyhemoglobin can confirm carbon monoxide poisoning, the level does not always correlate with the clinical picture; carbon monoxide poisoning involves other mechanisms as well, including binding to myoglobin, cytochrome oxidase, and direct effects on the central nervous system.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Carboxyhemoglobin/Hemoglobin.total
- Property
- MFr.DF
- Time
- Pt
- System
- BldV
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Carboxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Venous blood
- Short Name
- COHgb MFr.DF BldV
- Display Name
- Carboxyhemoglobin (BldV) [Pure mass fraction]
- Consumer Name Alpha Get Info
- Carboxyhemoglobin/Total Hgb, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.40
- Last Updated
- Version 2.40 (MIN)
- Order vs. Observation
- Observation
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG27557-4 | Carboxyhemoglobin/Hemoglobin.total| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Καρβοξυαιμοσφαιρίνη/Αιμοσφαιρίνη.ολική: Synonyms: MFr.DF Αιμοσφαιρίνη Καρβοξυαιμοσφαιρίνη |
es-ES | Spanish (Spain) | Carboxihemoglobina/Hemoglobina.total: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Carboxihemoglobina / Hemoglobina total: |
fr-CA | French (Canada) | Carboxyhémoglobine/Hémoglobine.totale: |
fr-FR | French (France) | Carboxyhémoglobine/hémoglobine totale: |
it-IT | Italian (Italy) | Carbossiemoglobina/Emoglobina.totale: Synonyms: Chimica Frazione di massa decimale Punto nel tempo (episodio) Sangue venoso |
nl-NL | Dutch (Netherlands) | carboxyhemoglobine/hemoglobine.totaal: |
pl-PL | Polish (Poland) | Karboksyhemoglobina/hemoglobina całkowita: Synonyms: Karboksyhemoglobina Karboksyhemoglobina/Hemoglobina całkowita |
pt-BR | Portuguese (Brazil) | Carboxihemoglobina/Hemoglobina.total: |
ru-RU | Russian (Russian Federation) | Карбоксигемоглобин/Гемоглобин.общий: Synonyms: Десятичное масс отношение Количественный Кровь Венозная Точка во времени; |
tr-TR | Turkish (Turkey) | Karboksihemoglobin/Hemoglobin.total: |
zh-CN | Chinese (China) | 碳氧血红蛋白/血红蛋白.总计: Synonyms: CO 血红蛋白; |
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