Version 2.78

46434-7 t(9;22)(q34.1;q11)(ABL1,BCR) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

Ratio of BCR-ABL1 compared to ABL1 (control gene).
Source: Regenstrief LOINC

Part Descriptions

LP150238-6   t(9;22)(q34.1;q11)(ABL1,BCR)
Chronic myelogenous leukemia (CML), acute lymphoblastic leukemia (ALL), and acute myeloid leukemia (AML) are associated with the fusion of the breakpoint cluster gene (BCR) at chromosome 22q11 to the Abelson gene (ABL1) at chromosome 9q23. The t(9;22)(BCR-ABL1) gene translocation leads to the cytogenetic finding known as the Philadelphia chromsome (Ph'). Various breakpoints within the BCR and ABL1 genes have been described. Most cases of CML are due to a fusion of BCR exon 13 (e13 or b2) or BCR exon 14 (e14 or b3) to the ABL exon 2 (a2). The b2a2 (e13a2) and b3a2 (e14a2) fused transcripts, also known as major break points, produce a 210-kDa protein (p210). The fused transcript resulting in a 190-kDa protein (e1a2 or less common e1a3), also known as minor break points, is found in approximately 75% of childhood ALL patients and 50% of adult ALL patients. Other rarely reported fused transcripts include e6a2, e19a2 (p230), e13a3, and e14a3. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(9;22)(q34.1;q11)(ABL1,BCR) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(9;22)(ABL1,BCR)/control Bld/T
Display Name
t(9;22)(q34.1;q11)(ABL1,BCR) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(9;22)(q34.1;q11)(ABL1,BCR)/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73
Change Reason
We believe this term was incorrectly stated as BCR/ABL based on original submission and knowledge of this test. Corrected Component to accurately represent testing for BCR-ABL1 transcripts compared to a control gene (e.g. ABL1).
Order vs. Observation
Both
Common Test Rank Get Info
9975

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: BCR-ABL Translokation (9,22) Ratio
es-ES Spanish (Spain) t(9;22)(q34.1;q11)(ABL1,BCR) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (9; 22) (q34.1; q11) (ABL1, BCR) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(9;22)(q34.1;q11)(ABL1,BCR) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(9;22)(q34.1;q11)(ABL1,BCR) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(9;22)(q34.1;q11)(ABL1,BCR), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
ko-KR Korean (Korea, Republic Of) 비시알/에비엘:수비:검사시점:전혈/조직:정량:분자유전
nl-NL Dutch (Netherlands) t(9;22)(q34.1;q11)(ABL1,BCR) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) BCR/ABL:NRto:Pt:Sg/Tecido:Qn:Genética molecular
Synonyms: Number ratio; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; PCR; Molecular genetics; ALL; BCR1; Chronic myeloid leukemia; CML; Breakpoint cluster region; D22S11; D22S662; PHL; MOLPATH.TRANSLOCATION; MOLPATH.TRANSLOCATION; Molecular pathology
ru-RU Russian (Russian Federation) t(9;22)(q34.1;q11)(ABL1,BCR) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(9;22)(q34.1;q11)(ABL1,BCR) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(9;22)(q34.1;q11)(ABL1,BCR) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: ABL CML JTK7 p150 v-abl Abelson murine leukemia viral oncogene homolog 1 v-abl Abelson 小鼠白血病病毒癌基因同源体 1 v-abl Abelson 小鼠白血病病毒肿瘤基因同源体 1 v-abl Abelson 小鼠白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科动物白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科白血病病毒致癌基因同源体 1 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 慢性粒细胞性白血病 慢性粒细胞白血病 慢性粒细胞白血病（Chronic myeloid leukemia，CML） 慢性髓系白血病 断点簇集区 断裂点丛集区 断裂点簇集区 断裂点聚集区 断裂点集中区 断裂点集中区（Breakpoint cluster region，BCR） 时刻;随机;随意;瞬间 易位(9;22)(q34.1;q11)(ABL1,BCR) 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 限制性断裂区

Example Units

Unit Source
{ratio} Example UCUM Units
ratio REGENSTRIEF

69380-4 t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 fusion transcript/control transcript (International Scale) [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor).
Source: LOINC partner 1

Part Descriptions

LP136109-8   control transcript (International Scale)
The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor). Source: LOINC partner 1

Fully-Specified Name

Component
t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 fusion transcript/control transcript (International Scale)
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(ABL1,BCR)p210/Control (IS) Bld/T
Display Name
t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 fusion transcript/control transcript (International Scale) Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(9;22)(q34.1;q11)(ABL1,BCR) B2a2+b3a2/control Transcript (International Scale), Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.73
Change Reason
Release 2.69: PROPERTY: Property updated to be consistent with similar term 55147-3. RelRto was not correct as the ratio is comparing measurements from the same System.; Previous Releases: Updated Component part to harmonize with ISCN guidelines and current LOINC nomenclature.
Order vs. Observation
Both
Common Test Rank Get Info
5224

Formula (Readable)

IS % ratio = local % ratio x conversion factor where local % ratio = 100 x BCR-ABL1/control gene

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 Tránscritos de fusión/transcrito control (escala internacional):Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (9; 22) (q34.1; q11) (ABL1, BCR) transcripción de fusión b2a2 + b3a2 / transcripción de control (escala internacional):Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-CA French (Canada) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 transcrit de fusion/Transcrit de contrôle (échelle internationale):Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
fr-FR French (France) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 transcrit de fusion/transcrit de référence (échelle internationale):Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
it-IT Italian (Italy) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2, trascritto di fusione/trascritto di controllo (Scala Internazionale):NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 fusietranscript/controle transcript (internationale schaal):aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
ru-RU Russian (Russian Federation) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 слияния транскрипт/контроль транскрипция (Международная Шкала):КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 füzyon transkript/kontrol transkripti (Uluslararası Ölçek):SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 融合转录物/对照转录物 (国际标尺):计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: ABL CML JTK7 p150 v-abl Abelson murine leukemia viral oncogene homolog 1 v-abl Abelson 小鼠白血病病毒癌基因同源体 1 v-abl Abelson 小鼠白血病病毒肿瘤基因同源体 1 v-abl Abelson 小鼠白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科动物白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科白血病病毒致癌基因同源体 1 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本;International Scale 慢性粒细胞性白血病 慢性粒细胞白血病 慢性粒细胞白血病（Chronic myeloid leukemia，CML） 慢性髓系白血病 断点簇集区 断裂点丛集区 断裂点簇集区 断裂点聚集区 断裂点集中区 断裂点集中区（Breakpoint cluster region，BCR） 时刻;随机;随意;瞬间 易位(9;22)(q34.1;q11)(ABL1,BCR) 易位(9;22)(q34.1;q11)(ABL1,BCR) b2a2 易位(9;22)(q34.1;q11)(ABL1,BCR) b2a2+b3a2 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 限制性断裂区

Example Units

Unit Source
% Example UCUM Units

69381-2 t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 fusion transcript/control transcript (International Scale) in Blood or Tissue by Molecular genetics method

Term Description

The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor).
Source: LOINC partner 1

Part Descriptions

LP136109-8   control transcript (International Scale)
The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor). Source: LOINC partner 1

Fully-Specified Name

Component
t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 fusion transcript/control transcript (International Scale)
Property
RelRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(ABL1,BCR)b2a2/Control (IS) Bld/T
Display Name
t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 fusion transcript/control transcript (International Scale) Molgen (Bld/Tiss) [Relative ratio]
Consumer Name Alpha Get Info
t(9;22)(q34.1;q11)(ABL1,BCR) B2a2/control Transcript (International Scale), Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.70
Change Reason
Updated Component part to harmonize with ISCN guidelines and current LOINC nomenclature.
Order vs. Observation
Both

Formula (Readable)

IS % ratio = local % ratio x conversion factor where local % ratio = 100 x BCR-ABL1/control gene

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 Tránscritos de fusión/transcrito control (escala internacional):Ratio relativo:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (9; 22) (q34.1; q11) (ABL1, BCR) transcripción de fusión b2a2 / transcripción de control (escala internacional):Razón relativa:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-CA French (Canada) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 transcrit de fusion/Transcrit de contrôle (échelle internationale):Ratio relatif:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
fr-FR French (France) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 transcrit de fusion/transcrit de référence (échelle internationale):Ratio relatif:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
it-IT Italian (Italy) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2, trascritto di fusione/trascritto di controllo (Scala Internazionale):RelRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto Relativo Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 fusietranscript/controle transcript (internationale schaal):relatieve verhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
ru-RU Russian (Russian Federation) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 слияния транскрипт/контроль транскрипция (Международная Шкала):ОтнПок:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественный Кровь Кровь или Ткань Относительный показатель;Относительное отношение Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 füzyon transkript/kontrol transkripti (Uluslararası Ölçek):GörOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(9;22)(q34.1;q11)(ABL1,BCR) b2a2 融合转录物/对照转录物 (国际标尺):相对比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: ABL CML JTK7 p150 v-abl Abelson murine leukemia viral oncogene homolog 1 v-abl Abelson 小鼠白血病病毒癌基因同源体 1 v-abl Abelson 小鼠白血病病毒肿瘤基因同源体 1 v-abl Abelson 小鼠白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科动物白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科白血病病毒致癌基因同源体 1 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本;International Scale 慢性粒细胞性白血病 慢性粒细胞白血病 慢性粒细胞白血病（Chronic myeloid leukemia，CML） 慢性髓系白血病 断点簇集区 断裂点丛集区 断裂点簇集区 断裂点聚集区 断裂点集中区 断裂点集中区（Breakpoint cluster region，BCR） 时刻;随机;随意;瞬间 易位(9;22)(q34.1;q11)(ABL1,BCR) 易位(9;22)(q34.1;q11)(ABL1,BCR) b2a2 未作说明的组织;组织;组织 & 涂片 来自于不同体系的两种分析物之比;相对比;相对比值 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 限制性断裂区

Example Units

Unit Source
% Example UCUM Units

69382-0 t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 fusion transcript/control transcript (International Scale) in Blood or Tissue by Molecular genetics method

Term Description

The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor).
Source: LOINC partner 1

Part Descriptions

LP136109-8   control transcript (International Scale)
The International Scale (IS) was established in 2005 to standardize quantitative BCR-ABL1 measurements across tests and laboratories. (Hughes et al., Blood 2006). The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS trial and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. Percent ratios on the IS are obtained by multiplying the percent ratio (100 x BCR-ABL1/control gene) determined at local labs by a test-specific conversion factor (IS % ratio = local % ratio x conversion factor). Source: LOINC partner 1

Fully-Specified Name

Component
t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 fusion transcript/control transcript (International Scale)
Property
RelRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(ABL1,BCR)b3a2/Control (IS) Bld/T
Display Name
t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 fusion transcript/control transcript (International Scale) Molgen (Bld/Tiss) [Relative ratio]
Consumer Name Alpha Get Info
t(9;22)(q34.1;q11)(ABL1,BCR) B3a2/control Transcript (International Scale), Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.70
Change Reason
Updated Component part to harmonize with ISCN guidelines and current LOINC nomenclature.
Order vs. Observation
Both

Formula (Readable)

IS % ratio = local % ratio x conversion factor where local % ratio = 100 x BCR-ABL1/control gene

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 Tránscritos de fusión/transcrito control (escala internacional):Ratio relativo:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (9; 22) (q34.1; q11) (ABL1, BCR) transcripción de fusión b3a2 / transcripción de control (escala internacional):Razón relativa:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-CA French (Canada) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 transcrit de fusion/Transcrit de contrôle (échelle internationale):Ratio relatif:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
fr-FR French (France) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 transcrit de fusion/transcrit de référence (échelle internationale):Ratio relatif:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
it-IT Italian (Italy) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2, trascritto di fusione/trascritto di controllo (Scala Internazionale):RelRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto Relativo Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 fusietranscript/controle transcript (internationale schaal):relatieve verhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
ru-RU Russian (Russian Federation) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 слияния транскрипт/контроль транскрипция (Международная Шкала):ОтнПок:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественный Кровь Кровь или Ткань Относительный показатель;Относительное отношение Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 füzyon transkript/kontrol transkripti (Uluslararası Ölçek):GörOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(9;22)(q34.1;q11)(ABL1,BCR) b3a2 融合转录物/对照转录物 (国际标尺):相对比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: ABL CML JTK7 p150 v-abl Abelson murine leukemia viral oncogene homolog 1 v-abl Abelson 小鼠白血病病毒癌基因同源体 1 v-abl Abelson 小鼠白血病病毒肿瘤基因同源体 1 v-abl Abelson 小鼠白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科动物白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科白血病病毒致癌基因同源体 1 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本;International Scale 慢性粒细胞性白血病 慢性粒细胞白血病 慢性粒细胞白血病（Chronic myeloid leukemia，CML） 慢性髓系白血病 断点簇集区 断裂点丛集区 断裂点簇集区 断裂点聚集区 断裂点集中区 断裂点集中区（Breakpoint cluster region，BCR） 时刻;随机;随意;瞬间 易位(9;22)(q34.1;q11)(ABL1,BCR) 易位(9;22)(q34.1;q11)(ABL1,BCR) b3a2 未作说明的组织;组织;组织 & 涂片 来自于不同体系的两种分析物之比;相对比;相对比值 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 限制性断裂区

Example Units

Unit Source
% Example UCUM Units

52132-8 t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Fully-Specified Name

Component
t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(ABL1,BCR)e1a2/control Bld/T
Display Name
t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(9;22)(q34.1;q11)(ABL1,BCR) E1a2/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.73
Change Reason
We changed the property from NFr to NRto. We had misunderstood how this test was done - it counts the number of transcripts of the two transcripts produced (usually) by PCR. Updated Component part to harmonize with ISCN guidelines and current LOINC nomenclature.
Order vs. Observation
Observation
Common Test Rank Get Info
4256

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method
52135-1 t(9;22)(q34.1;q11)(ABL1,BCR) transcript detection panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: BCR-ABL Translokation (9,22) e1a2 Ratio
es-ES Spanish (Spain) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (9; 22) (q34.1; q11) (ABL1, BCR) transcripción de fusión e1a2 / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-CA French (Canada) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
fr-FR French (France) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
it-IT Italian (Italy) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2, trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) BCR-ABL1 e1a2 transcrito de fusão/AcL 1 transcrito:NFr:Pt:Sg/Tecido:Qn:Genética molecular
Synonyms: ; Fr; Number fraction; Percent; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; PCR; Molecular genetics; ALL; BCR1; Chronic myeloid leukemia; CML; Breakpoint cluster region; D22S11; D22S662; PHL; v-Acl Acelson murine leukemia viral oncogene homolog 1; AcL; JTK7; p150; Molecular pathology
ru-RU Russian (Russian Federation) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(9;22)(q34.1;q11)(ABL1,BCR) e1a2 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: ABL CML JTK7 p150 v-abl Abelson murine leukemia viral oncogene homolog 1 v-abl Abelson 小鼠白血病病毒癌基因同源体 1 v-abl Abelson 小鼠白血病病毒肿瘤基因同源体 1 v-abl Abelson 小鼠白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科动物白血病病毒致癌基因同源体 1 v-abl Abelson 鼠科白血病病毒致癌基因同源体 1 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 慢性粒细胞性白血病 慢性粒细胞白血病 慢性粒细胞白血病（Chronic myeloid leukemia，CML） 慢性髓系白血病 断点簇集区 断裂点丛集区 断裂点簇集区 断裂点聚集区 断裂点集中区 断裂点集中区（Breakpoint cluster region，BCR） 时刻;随机;随意;瞬间 易位(9;22)(q34.1;q11)(ABL1,BCR) 易位(9;22)(q34.1;q11)(ABL1,BCR) e1a2 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 限制性断裂区

Example Units

Unit Source
% Example UCUM Units
% REGENSTRIEF

72207-4 t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

Translocations between chromosomes 8 and 21, resulting in a fused transcript between RUNXT1 (8q22) and RUNX1 (21q22.3), can be detected with real-time PCR. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Part Descriptions

LP19847-0   t(8;21)(q22;q22.3)(RUNX1T1,RUNX1)
Translocation (8;21) resulting in a fused transcript between RUNX1T1 (also known as ETO) and RUNX1 genes is one of the most common chromosomal translocations found in acute myeloid leukemia (AML). The RUNX1T1-RUNX1 fusion transcript is found in approximately 12% of all AML patients. RUNX1 is a transcription factor that regulates critical processes in many aspects of hematopoiesis and is essential in defining the final hematopoietic stem cell. It is involved in many forms of chromosomal translocations in leukemia. In addition, many hematological diseases have been associated with mutations in RUNX1. PMID: 22201794 Source: Regenstrief LOINC, PMID: 22201794

Fully-Specified Name

Component
t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(8;21)(RUNX1T1,RUNX1)/control Bld/T
Display Name
t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(8;21)(q22;q22.3)(RUNX1T1,RUNX1)/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
6138

Formula (Readable)

Normalized copy number (NCN) = Fusion gene copy number (FGCN) / Control gene copy number (CGCN)

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (8; 21) (q22; q22.3) (RUNX1T1, RUNX1) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(8;21)(q22;q22.3)(RUNX1T1,RUNX1) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: AML1 CDR ETO MGC2796 MTG8 RUNX1T1 T(8,21)(CBFA2T1,CBFA2) 基因易位;T(8,21)(CBFA2T1,CBFA2) 易位 ZMYND2 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 急性髓性白血病 1 急性髓性白血病 1 易位 1, 细胞周期蛋白-D 相关性 急性髓性白血病 1 染色体易位 1, 细胞周期蛋白-D 相关性 急性髓系白细胞 1 急性髓系白细胞 1 易位 1, 细胞周期蛋白-D 相关性 急性髓系白细胞 1 易位 1, 细胞周期蛋白-D 相关性（Acute myelogenous leukemia 1 translocation 1, cyclin-D related） 急性髓系白细胞 1 染色体易位 1, 细胞周期蛋白-D 相关性 急性髓系白细胞 1（Acute myeloid leukemia 1） 急性髓细胞白血病 1 急性髓细胞白血病 1 易位 1, 细胞周期蛋白-D 相关性 急性髓细胞白血病 1 染色体易位 1, 细胞周期蛋白-D 相关性 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体 8q22 之上的 AML1T1L 髓系易位基因 核心结合因子侏儒结构域 alpha 亚基 2 核心结合因子侏儒结构域α亚基 2 核心结合因子矮小域 alpha 亚基 2 核心结合因子矮小域α亚基 2 核心结合因子矮小结构域 alpha 亚基 2 核心结合因子矮小结构域 alpha 亚基 2（Core binding factor runt domain alpha subunit 2） 核心结合因子矮小结构域α亚基 2 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液

Example Units

Unit Source
% Example UCUM Units

72210-8 inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

A pericentric inversion of chromosome 16, inv(16)(p13;q22), results in a fused transcript between MYH11 (16p13.1) and CBFB (16q22.1) genes and is known to cause acute myeloid leukemia (AML). Techniques like real-time PCR are used to detect the MYH11-CBFB fused transcript. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Part Descriptions

LP146062-7   inv(16)(p13.1;q22.1)(MYH11,CBFB)
The inv(16)(p13.1;q22.1) CBFB-MYH11 fusion transcript is a chromosomal abnormality associated with acute myelomonocytic leukemia (AML). This results in the formation of a chimeric protein between core binding factor beta and smooth muscle myosin heavy chain 11. Positive results are indicative of AML subtype M4E0. Source: Regenstrief LOINC

Fully-Specified Name

Component
inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
inv(16)(p13;q22)/control Bld/T
Display Name
inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
inv(16)(p13.1;q22.1)(MYH11,CBFB)/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.INV
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
5676

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) inv(16)(p13.1;q22.1)(MYH11,CBFB) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) inv (16) (p13.1; q22.1) (MYH11, CBFB) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) inv(16)(p13.1;q22.1)(MYH11,CBFB) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) inv(16)(p13.1;q22.1)(MYH11,CBFB) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) inv(16)(p13.1;q22.1)(MYH11,CBFB), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Inversione genetica Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) inv(16)(p13.1;q22.1)(MYH11,CBFB) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) inv(16)(p13.1;q22.1)(MYH11,CBFB) transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) inv(16)(p13.1;q22.1)(MYH11,CBFB) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) inv(16)(p13.1;q22.1)(MYH11,CBFB) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) inv(16)(p13.1;q22.1)(MYH11,CBFB) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: 倒位(16)(p13.1;q22.1)(MYH11,CBFB);基因倒位;基因倒置;倒位;倒置;gene inversion 全血或组织;血液/组织;血液或组织 分子病理学.基因倒位;分子病理学试验.基因倒位;分子病理学试验类.倒位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液

Example Units

Unit Source
% Example UCUM Units

72214-0 t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

A balanced reciprocal translocation involving chromosomes 15 and 17, (15;17)(q22;q21), results in a fused transcript between PML and RARA genes. This gene fusion produces the PML-RARA fusion protein, a transcriptional repressor, which causes acute promyelocytic Leukemia (APL). Depending on the breakpoint within the PML gene, various fusion transcripts will be generated: long (L or bcr1), variant (V or bcr2), and short (S or bcr3). Techniques like real-time PCR are used to detect the PML-RARA fused transcripts and breakpoints. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Part Descriptions

LP156105-1   t(15;17)(q24.1;q21.1)(PML,RARA) bcr3
Three different breakpoint cluster regions (BCR1, BCR2, BCR3) on chromosome 15 leads to the formation of various types of PML-RARA fusion transcripts. BCR1 and BCR3 are most frequently involved in acute promyelocytic leukemia (APL), and BCR2 leads to several different products due to different breakpoints within this cluster. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(15;17) BCR3/control Bld/T
Display Name
t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(15;17)(q24.1;q21.1)(PML,RARA) Bcr3/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
8893

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (15; 17) (q24.1; q21.1) (PML, RARA) transcripción de fusión bcr3 / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-CA French (Canada) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
fr-FR French (France) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
it-IT Italian (Italy) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3, trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Промиелоцитарный лейкоз Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(15;17)(q24.1;q21.1)(PML,RARA) bcr3 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: MYL NR1B1 PML-1 PML-2 PML-3 PML-3B PML-X RAR alpha 型 RAR α型 RARalpha RARα 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 前髓细胞白血病 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 早幼粒细胞性白血病 早幼粒细胞白血病 早幼粒细胞白血病（Promyelocytic leukemia，PML） 时刻;随机;随意;瞬间 易位(15;17)(q24.1;q21.1)(PML,RARA) 易位(15;17)(q24.1;q21.1)(PML,RARA) bcr3 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 视黄酸受体 alpha 视黄酸受体 alpha（Retinoic acid receptor alpha，RARA，RARalpha，RAR alpha） 视黄酸受体 α

Example Units

Unit Source
% Example UCUM Units

72215-7 t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

A balanced reciprocal translocation involving chromosomes 15 and 17, (15;17)(q22;q21), results in a fused transcript between PML and RARA genes. This gene fusion produces the PML-RARA fusion protein, a transcriptional repressor, which causes acute promyelocytic Leukemia (APL). Depending on the breakpoint within the PML gene, various fusion transcripts will be generated: long (L or bcr1), variant (V or bcr2), and short (S or bcr3). Techniques like real-time PCR are used to detect the PML-RARA fused transcripts and breakpoints. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Part Descriptions

LP101591-8   t(15;17)(q24.1;q21.1)(PML,RARA) bcr2
Three different breakpoint cluster regions (BCR1, BCR2, BCR3) on chromosome 15 leads to the formation of various types of PML-RARA fusion transcripts. BCR1 and BCR3 are most frequently involved in acute promyelocytic leukemia (APL), and BCR2 leads to several different products due to different breakpoints within this cluster. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(15;17) BCR2/control Bld/T
Display Name
t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(15;17)(q24.1;q21.1)(PML,RARA) Bcr2/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
10063

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) bcr2 t(15;17)(q24.1;q21.1)(PML,RARA) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (15; 17) (q24.1; q21.1) (PML, RARA) transcripción de fusión bcr2 / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2, trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Промиелоцитарный лейкоз Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(15;17)(q24.1;q21.1)(PML,RARA) bcr2 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: MYL NR1B1 PML-1 PML-2 PML-3 PML-3B PML-X RAR alpha 型 RAR α型 RARalpha RARα 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 前髓细胞白血病 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 早幼粒细胞性白血病 早幼粒细胞白血病 早幼粒细胞白血病（Promyelocytic leukemia，PML） 时刻;随机;随意;瞬间 易位(15;17)(q24.1;q21.1)(PML,RARA) 易位(15;17)(q24.1;q21.1)(PML,RARA) bcr2 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 视黄酸受体 alpha 视黄酸受体 alpha（Retinoic acid receptor alpha，RARA，RARalpha，RAR alpha） 视黄酸受体 α

Example Units

Unit Source
% Example UCUM Units

72216-5 t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

A balanced reciprocal translocation involving chromosomes 15 and 17, (15;17)(q22;q21), results in a fused transcript between PML and RARA genes. This gene fusion produces the PML-RARA fusion protein, a transcriptional repressor, which causes acute promyelocytic Leukemia (APL). Depending on the breakpoint within the PML gene, various fusion transcripts will be generated: long (L or bcr1), variant (V or bcr2), and short (S or bcr3). Techniques like real-time PCR are used to detect the PML-RARA fused transcripts and breakpoints. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Part Descriptions

LP101592-6   t(15;17)(q24.1;q21.1)(PML,RARA) bcr1
Three different breakpoint cluster regions (BCR1, BCR2, BCR3) on chromosome 15 leads to the formation of various types of PML-RARA fusion transcripts. BCR1 and BCR3 are most frequently involved in acute promyelocytic leukemia (APL), and BCR2 leads to several different products due to different breakpoints within this cluster. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(15;17) BCR1/control Bld/T
Display Name
t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(15;17)(q24.1;q21.1)(PML,RARA) Bcr1/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
8858

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: PML-RARA/BCR1 quantitativ
es-ES Spanish (Spain) bcr1 t(15;17)(q24.1;q21.1)(PML,RARA) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (15; 17) (q24.1; q21.1) (PML, RARA) transcripción de fusión bcr1 / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1, trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Промиелоцитарный лейкоз Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: MYL NR1B1 PML-1 PML-2 PML-3 PML-3B PML-X RAR alpha 型 RAR α型 RARalpha RARα 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 前髓细胞白血病 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 早幼粒细胞性白血病 早幼粒细胞白血病 早幼粒细胞白血病（Promyelocytic leukemia，PML） 时刻;随机;随意;瞬间 易位(15;17)(q24.1;q21.1)(PML,RARA) 易位(15;17)(q24.1;q21.1)(PML,RARA) bcr1 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 视黄酸受体 alpha 视黄酸受体 alpha（Retinoic acid receptor alpha，RARA，RARalpha，RAR alpha） 视黄酸受体 α

Example Units

Unit Source
% Example UCUM Units

72218-1 t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Part Descriptions

LP19835-5   t(12;21)(p13;q22.3)(ETV6,RUNX1)
The chromosomal translocation t(12;21)(p13;q22) results in a fused transcript between ETV6-RUNX1 (TEL-AML1) genes and is the most common translocation in B cell childhood acute lymphoblastic leukemia (ALL), accounting for 25% of childhood ALL. Molecular and cytogenetic techniques such as real-time PCR and FISH are used to detect the ETV6-RUNX1 fused transcripts. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(12;21)(ETV6,RUNX1)/control Bld/T
Display Name
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(12;21)(p13;q22.3)(ETV6,RUNX1)/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(12;21)(p13;q22.3)(ETV6,RUNX1) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (12; 21) (p13; q22.3) (ETV6, RUNX1) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(12;21)(p13;q22.3)(ETV6,RUNX1), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(12;21)(p13;q22.3)(ETV6,RUNX1) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(12;21)(p13;q22.3)(ETV6,RUNX1) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(12;21)(p13;q22.3)(ETV6,RUNX1) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(12;21)(p13;q22.3)(ETV6,RUNX1) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: AML1 ETS 变体基因 6 ETS 差异基因 6 ETS 突变体基因 6 ETS 突变基因 6 ETS 突变基因 6（ets variant gene 6，ETV6） T(12,21)(ETV6,CBFA2) 基因易位;T(12,21)(ETV6,CBFA2) 易位 TEL TEL 癌基因 TEL 癌基因（Tel oncogene） TEL 致癌基因 TEL1 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 急性髓性白血病 1 急性髓系白细胞 1 急性髓系白细胞 1（Acute myeloid leukemia 1） 急性髓细胞白血病 1 时刻;随机;随意;瞬间 易位 ETS 白血病 易位 ETS 白血病（Translocation ets leukemia，TEL） 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液

Example Units

Unit Source
% Example UCUM Units

72274-4 t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Part Descriptions

LP150268-3   t(15;17)(q24.1;q21.1)(PML,RARA)
The fusion of promyelocytic leukemia (PML, chromosome 15q24.1) and retinoic acid receptor alpha (RARA, chromosome 17q21.1) genes occurs due to a chromosomal translocation. The fused genes can be detected by various molecular techniques, including FISH and real-time quantitative polymerase chain reaction (RT-qPCR). The test is used to diagnose Acute Promyelocytic Leukemia (APL), detect residual or recurrent APL, and to monitor PML-RARA levels in patients with APL. The assay can be done on whole blood (plasma or cell-based) and bone marrow. Long, variant and/or short isoforms of PML-RARA fusion transcripts may be identified. The ratio of PML-RARA fusion transcript to a control gene (e.g. ABL1) may be reported for positive samples. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(15;17)(PML,RARA)/control Bld/T
Display Name
t(15;17)(q24.1;q21.1)(PML,RARA) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(15;17)(q24.1;q21.1)(PML,RARA)/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(15;17)(q24.1;q21.1)(PML,RARA) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (15; 17) (q24.1; q21.1) (PML, RARA) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(15;17)(q24.1;q21.1)(PML,RARA) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(15;17)(q24.1;q21.1)(PML,RARA) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(15;17)(q24.1;q21.1)(PML,RARA), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(15;17)(q24.1;q21.1)(PML,RARA) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(15;17)(q24.1;q21.1)(PML,RARA) transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(15;17)(q24.1;q21.1)(PML,RARA) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Промиелоцитарный лейкоз Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(15;17)(q24.1;q21.1)(PML,RARA) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(15;17)(q24.1;q21.1)(PML,RARA) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: MYL NR1B1 PML-1 PML-2 PML-3 PML-3B PML-X RAR alpha 型 RAR α型 RARalpha RARα 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 前髓细胞白血病 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 早幼粒细胞性白血病 早幼粒细胞白血病 早幼粒细胞白血病（Promyelocytic leukemia，PML） 时刻;随机;随意;瞬间 易位(15;17)(q24.1;q21.1)(PML,RARA) 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 视黄酸受体 alpha 视黄酸受体 alpha（Retinoic acid receptor alpha，RARA，RARalpha，RAR alpha） 视黄酸受体 α

Example Units

Unit Source
{ratio} Example UCUM Units

72312-2 t(1;19)(q23.3;p13.3)(PBX1,TCF3) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

A translocation involving chromosomes 1 and 19, t(1;19)(q23;p13), results in a fused transcript between TCF3 (formerly E2A) and PBX1 (formerly prl) genes. The TCF3-PBX1 fusion gene is found in approximately 3% of childhood and adult precursor-B acute lymphoblastic leukemia (ALL). This code is based on, but not limited to, Ispogen's E2A-PBX1 FusionQuant® kit, which uses real-time Quantitative RQ-PCR to quantify the expression level of specific TCF3(E2A)-PBX1 fusion gene transcripts relative to a control gene transcript (e.g. ABL1). From the manufacturer's website (2012), "Quantification of E2A-PBX1 fusion gene transcripts has been standardized in the EAC (Europe Against Cancer) program [Gabert J et al. Leukemia. 2003, Beillard E et al. Leukemia. 2003], and IPSOGEN FusionQuant® kits use this validated technology to calibrate and normalize RQ-PCR results."
Source: Regenstrief LOINC

Part Descriptions

LP19829-8   t(1;19)(q23.3;p13.3)(PBX1,TCF3)
Chromosomal translocation t(1;19)(q23.3;p13.3) PBX1/TCF3 is caused by a breakpoint in 19p13.3 and occurs in two different forms: 1) a balanced form found in one fourth of cases with a der(1) and a der(19) and 2) an unbalanced form found in 3/4 cases with 2 normal chromosomes 1, a der(19), and 1 normal chromosome 19. This translocation is mostly found in acute lymphoblastic leukemia (ALL), L1/L2 type, as well as L3-like ALL, T-lineage ALL (T-ALL), non-Hodgkin lymphomas (NHL), and acute myeloid leukemias (AML).[Atlas Genetics Oncology:t0119ID1048] Source: Regenstrief LOINC, t(1;19)(q23;p13) TCF3/PBX1

Fully-Specified Name

Component
t(1;19)(q23.3;p13.3)(PBX1,TCF3) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(1;19)(PBX1,TCF3)/control Bld/T
Display Name
t(1;19)(q23.3;p13.3)(PBX1,TCF3) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(1;19)(q23.3;p13.3)(PBX1,TCF3)/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(1;19)(q23.3;p13.3)(PBX1,TCF3) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (1; 19) (q23.3; p13.3) (PBX1, TCF3) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(1;19)(q23.3;p13.3)(PBX1,TCF3) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(1;19)(q23.3;p13.3)(PBX1,TCF3) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(1;19)(q23.3;p13.3)(PBX1,TCF3), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(1;19)(q23.3;p13.3)(PBX1,TCF3) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(1;19)(q23.3;p13.3)(PBX1,TCF3) transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(1;19)(q23.3;p13.3)(PBX1,TCF3) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(1;19)(q23.3;p13.3)(PBX1,TCF3) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(1;19)(q23.3;p13.3)(PBX1,TCF3) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: Ⅰ E2A 免疫球蛋白增强子结合因子 E12/E47 E2A 免疫球蛋白增强子结合因子 E12/E47（E2A Immunoglobulin enhancer binding factors E12/E47） I ITF1 PBXP1 T(1,19)(PBX1,TCF3) 基因易位;T(1,19)(PBX1,TCF3) 易位 免疫球蛋白转录因子 1 免疫球蛋白转录因子 1（Immunoglobulin transcription factor 1，ITF1） 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 前 B 细胞白血病转录因子-1 前 B-细胞白血病转录因子-1 前 B-细胞白血病转录因子-1（Pre-B cell leukemia transcription factor-1，PBX1，PBXP1） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 转录因子 3 转录因子 3（Transcription factor 3，TCF3）

Example Units

Unit Source
% Example UCUM Units

72313-0 t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method

Term Description

A translocation involving chromosomes 4 and 11, t(4;11)(q21.3;q23), results in a fused transcript between AFF1 and MLL genes. The AFF1-MLL fusion gene is associated with childhood and adult acute lymphoblastic leukemia (ALL) as well as infant acute leukemia. This code is based on, but not limited to, Ispogen's FusionQuant® kit, which uses real-time Quantitative RQ-PCR to quantify the expression level of specific AFF1-MLL fusion transcripts relative to a control gene transcript (e.g. ABL1). Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
Source: Regenstrief LOINC

Fully-Specified Name

Component
t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript
Property
NRto
Time
Pt
System
Bld/Tiss
Scale
Qn
Method
Molgen

Additional Names

Short Name
t(4;11)(AFF1,MLL)/control Bld/T
Display Name
t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]
Consumer Name Alpha Get Info
t(4;11)(q21.3;q23)(AFF1,MLL)/control Transcript, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.42
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
72104-3 Acute and chronic leukemia fusion transcript per control transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) t(4;11)(q21.3;q23)(AFF1,MLL) Tránscritos de fusión/transcrito control:Relación de número:Punto temporal:Sangre o tejido:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) t (4; 11) (q21.3; q23) (AFF1, MLL) transcripción de fusión / transcripción de control:Proporción numérica:Punto temporal:Sangre o tejido:Cuantitativo:Genética molecular
fr-FR French (France) t(4;11)(q21.3;q23)(AFF1,MLL) transcrit de fusion/transcrit de référence:Nombre/Nombre:Ponctuel:Sang/Tissu:Numérique:Biologie moléculaire
fr-CA French (Canada) t(4;11)(q21.3;q23)(AFF1,MLL) transcrit de fusion/Transcrit de contrôle:Ratio de numérique:Temps ponctuel:Sang/Tissu:Quantitatif:Molgen
it-IT Italian (Italy) t(4;11)(q21.3;q23)(AFF1,MLL), trascritto di fusione/trascritto di controllo:NRto:Pt:Sangue/Tess:Qn:Molgen
Synonyms: Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
nl-NL Dutch (Netherlands) t(4;11)(q21.3;q23)(AFF1,MLL) fusietranscript/controle transcript:aantalsverhouding:moment:bloed of weefsel:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(4;11)(q21.3;q23)(AFF1,MLL) transcrição de fusão/controle de transcrição::Pt:Sg/Tecido:Qn:Genética molecular
ru-RU Russian (Russian Federation) t(4;11)(q21.3;q23)(AFF1,MLL) слияния транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Кр/Тк:Колич:МолГен
Synonyms: Количественное отношение Количественный Кровь Кровь или Ткань Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(4;11)(q21.3;q23)(AFF1,MLL) füzyon transkript/kontrol transkripti:SayOr:Zmlı:Kan/Dk:Kant:Molgen
zh-CN Chinese (China) t(4;11)(q21.3;q23)(AFF1,MLL) 融合转录物/对照转录物:计数型比率:时间点:全血/组织:定量型:分子遗传学类实验室方法
Synonyms: AF4 ALL1 ALL-1 FEL HRX HTRX HTRX1 T(4,11)(MLLT2,MLL) 基因易位;T(4,11)(MLLT2,MLL) 易位 TRX1 三胸同源基因 三胸同源基因（Homolog of trithorax） 三胸同源物 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液 髓/淋巴混合系白血病 (三胸(果蝇)) 髓/淋巴混合系白血病 (三胸(果蝇)同源基因) 髓/淋系或混合型白血病 (三胸(果蝇)) 髓/淋系或混合型白血病 (三胸(果蝇)同源基因) 髓/淋系或混合性白血病 (三胸(果蝇)) 髓/淋系或混合性白血病 (三胸(果蝇)同源基因) 髓/淋系或混合系白血病 (三胸(果蝇)) 髓/淋系或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴样或混合型白血病 (三胸(果蝇)) 髓系/淋巴样或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴样或混合性白血病 (三胸(果蝇)) 髓系/淋巴样或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴样或混合系白血病 (三胸(果蝇)) 髓系/淋巴样或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合型白血病 (三胸(果蝇)) 髓系/淋巴系或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合性白血病 (三胸(果蝇)) 髓系/淋巴系或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合系白血病 (三胸(果蝇)) 髓系/淋巴系或混合系白血病 (三胸(果蝇))（Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila))） 髓系/淋巴系或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴系或混合系白血病 (三胸(果蝇)同源基因) （Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog)） 髓系/淋巴细胞性或混合型白血病 (三胸(果蝇)) 髓系/淋巴细胞性或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞性或混合性白血病 (三胸(果蝇)) 髓系/淋巴细胞性或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞性或混合系白血病 (三胸(果蝇)) 髓系/淋巴细胞性或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞或混合型白血病 (三胸(果蝇)) 髓系/淋巴细胞或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞或混合性白血病 (三胸(果蝇)) 髓系/淋巴细胞或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋巴细胞或混合系白血病 (三胸(果蝇)) 髓系/淋巴细胞或混合系白血病 (三胸(果蝇)同源基因) 髓系/淋系或混合型白血病 (三胸(果蝇)) 髓系/淋系或混合型白血病 (三胸(果蝇)同源基因) 髓系/淋系或混合性白血病 (三胸(果蝇)) 髓系/淋系或混合性白血病 (三胸(果蝇)同源基因) 髓系/淋系或混合系白血病 (三胸(果蝇)) 髓系/淋系或混合系白血病 (三胸(果蝇)同源基因)

Example Units

Unit Source
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