Version 2.78

Term Description

The quantification of NPM1 mutation D (c.960insCCTG) transcripts are compared to a control gene (e.g. ABL1) by real-time PCR (RT-qPCR). NPM1 primers and probes spanning exons 11 and 12 may be used to detect quantify the NPM1 mutation transcripts. Results are based on the normalized copy number [NPM1 mut D copy number/ABL1 copy number) x 100]. This test is based on, but not limited to, IPSOGEN'S NPM1-B/D MutaQuant Kit, which is used as research tool (as of 2012) for the quantification of NPM1-D transcripts in samples previously identified as carrying the NPM1 mutation D. The results are used to monitor the decrease of NPM1 mutD expression.
Source: Regenstrief LOINC

Fully-Specified Name

Component
NPM1 gene.c.960insCCTG transcript/control transcript
Property
NRto
Time
Pt
System
Bone mar
Scale
Qn
Method
Molgen

Additional Names

Long Common Name
NPM1 gene c.960insCCTG transcript/control transcript [# Ratio] in Bone marrow by Molecular genetics method
Short Name
NPM1 gene mut D/control Mar
Display Name
NPM1 gene c.960insCCTG transcript/control transcript Molgen (BM) [# ratio]
Consumer Name Alpha Get Info
NPM1 gene c.960insCCTG transcript/control Transcript, Bone marrow

Basic Attributes

Class
MOLPATH.MUT
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.50
Order vs. Observation
Both

Formula (Readable)

NCN = (CN NPM1 mut D/CN ABL) x 100 where NCN= normalized copy number CN = copy number

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gen NPM1 transcrito c.960insCCTG/transcrito control:Relación de número:Punto temporal:Médula ósea:Qn:Genética molecular
Synonyms: Cuantitativo
es-MX Spanish (Mexico) NPM1 gene.c.960insCCTG transcripción / transcripción de control:Proporción numérica:Punto temporal:Médula ósea:Cuantitativo:Genética molecular
fr-FR French (France) NPM1 gène mutation c.960insCCTG transcrit/transcrit de référence:Nombre/Nombre:Ponctuel:Moelle osseuse:Numérique:Biologie moléculaire
it-IT Italian (Italy) NPM1 c.960insCCTG, gene, trascritto/trascritto di controllo:NRto:Pt:Mid oss:Qn:Molgen
Synonyms: Gene NPM1 Genetica molecolare Midollo osseo Mutazione genica Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Trascritto gene NPM1 c.960insCCTG
nl-NL Dutch (Netherlands) NPM1-gen.c.960insCCTG transcript/controle transcript:aantalsverhouding:moment:beenmerg:kwantitatief:moleculair genetisch onderzoek
Synonyms: molgen NPM1 gen
pt-BR Portuguese (Brazil) NPM1 gene.c.960insCCTG transcrição/controle de transcrição::Pt:MedOssea:Qn:Genética molecular
ru-RU Russian (Russian Federation) NPM1 ген.c.960insCCTG транскрипт/контрольный транскрипт:КолОтн:ТчкВрм:Костный мозг:Колич:МолГен
Synonyms: Количественное отношение Количественный Точка во времени;Момент
tr-TR Turkish (Turkey) NPM1 geni.c.960insCCTG transkript/kontrol transkripti:SayOr:Zmlı:Kem il:Kant:Molgen
zh-CN Chinese (China) NPM1 基因.c.960insCCTG 转录物/对照转录物:计数型比率:时间点:骨髓:定量型:分子遗传学类实验室方法
Synonyms: B23;MGC104254;NPM;nucleolar phosphoprotein B23;nucleophosmin 1;nucleophosmin/nucleoplasmin family, member 1;numatrin;nucleophosmin (nucleolar phosphoprotein B23, numatrin);核仁磷蛋白 B23;核仁磷酸化蛋白 B23;核磷蛋白 1;核磷蛋白/核磷蛋白家族, 成员1;numatrin;核磷蛋白 (核仁磷蛋白 B23, numatrin, N C 型;丙;丙型 NPM NPM1 基因.c.960insCCTG 转录物（转录本、转录产物、转录子、转录）;NPM1 基因.c.960insCCTG 转录;NPM1 基因.c.960insCCTG 转录物 Numatrin 分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 对照转录物（转录本、转录产物、转录子、转录）;对照基因转录本;控制转录本 时刻;随机;随意;瞬间 核仁磷朊 b23 核仁磷蛋白 b23 核仁磷蛋白 b23（Nucleolar phosphoprotein b23，B23） 核仁磷蛋白 b23（Nucleophosmin，NPM，B23，Numatrin，NO38） 核仁磷酸化蛋白 核磷蛋白 核磷蛋白 1 核磷蛋白 1（Nucleophosmin，NPM，B23，N38，Numatrin） 核磷蛋白（Nuclear phosphoprotein，NPM） 遗传基因;遗传因子;吉恩;生物基因 骨骼;骨头 髓

Example Units

Unit Source
% Example UCUM Units

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