72368-4

t(11;14)(q13;q32)(CCND1,IGH) fusion transcript [Presence] in Bone marrow by Molecular genetics method

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Term Description

PCR-based assays are used to detect and monitor CCND1-IGH t(11;14)(q13;q32) gene translocations in patients with lymphoproliferations. This test is based on, but not limited to the IdentiClone BCL1/JH Translocation Assay, which targets the MTC region of the CCND1/IGH gene fusion and amplifies genomic DNA between primers that target the CCND1 (also known as BCL1) gene and the conserved joining (JH) regions of the IGH gene.

Part Description

LP19830-6 t(11;14)(q13;q32)(CCND1,IGH)
The CCND1-IGH t(11;14)(q13;q32) gene translocation is primarily found in mantle cell lymphoma (MCL) (50-70%) as well as B prolymphocytic leukemia (B-PLL), plasma cell leukemia (PCL), splenic lymphoma with villous lymphocytes (SLVL), chronic lymphocytic leukemia (CLL), and multiple myeloma (MM).[Huret, JL, t(11;14)(q13;q32). Atlas Genet Cytogenet Oncol Haematol. 1998;2(4):129-131.] Source: Regenstrief LOINC , t(11;14)(q13;q32) IGH/CCND1

Fully-Specified Name

Component: t(11;14)(q13;q32)(CCND1,IGH) fusion transcript
Property: PrThr
Time: Pt
System: Bone mar
Scale: Ord
Method: Molgen

Additional Names

Long Common Name: t(11;14)(q13;q32)(CCND1,IGH) fusion transcript [Presence] in Bone marrow by Molecular genetics method
Short Name: t(11;14)(CCND1,IGH) Mar Ql
Display Name: t(11;14)(q13;q32)(CCND1,IGH) fusion transcript Molgen Ql (BM)
Consumer Name Alpha Get Info: t(11;14)(q13;q32)(CCND1,IGH) fusion transcript analysis, Bone marrow

Basic Attributes

Class: MOLPATH.TRNLOC
Type: Laboratory
First Released: Version 2.42
Last Updated: Version 2.56 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
de-AT	German (Austria)	Synonyms: CCND1/IGH Translokation (11,14) /KM
el-GR	Greek (Greece)	t(11;14)(q13;q32)(CCND1,IGH) μεταγραφή συγχώνευσης:PrThr:Pt:Μυελός των οστών:Ord:Μοριακή γενετική Synonyms: PrThr t(11;14)(q13;q32)(CCND1,IGH)
es-ES	Spanish (Spain)	t(11;14)(q13;q32)(CCND1,IGH) Tránscritos de fusión:PrThr:Punto temporal:Médula ósea:Ord:Genética molecular
es-MX	Spanish (Mexico)	t (11; 14) (q13; q32) (CCND1, IGH) transcripción de fusión:Presencia o umbral:Punto temporal:Médula ósea:Ordinal:Genética molecular
fr-FR	French (France)	t(11;14)(q13;q32)(CCND1,IGH) transcrit de fusion:Présence/Seuil:Ponctuel:Moelle osseuse:Qualitatif:Biologie moléculaire
fr-CA	French (Canada)	t(11;14)(q13;q32)(CCND1,IGH) transcrit de fusion:Présence-Seuil:Temps ponctuel:Moelle osseuse:Ordinal:Molgen
it-IT	Italian (Italy)	t(11;14)(q13;q32)(CCND1,IGH), trascritto di fusione:PrThr:Pt:Mid oss:Ord:Molgen Synonyms: Genetica molecolare Midollo osseo Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Traslocazione genetica
nl-NL	Dutch (Netherlands)	t(11;14)(q13;q32)(CCND1,IGH) fusietranscript:aanwezigheid:moment:beenmerg:ordinaal:moleculair genetisch onderzoek Synonyms: molgen
pl-PL	Polish (Poland)	t (11; 14) (q13; q32) (CCND1,IGH) transkrypt fuzyjny:granica wykrywalności:punkt w czasie:szpik kostny:półilościowy:genetyka molekularna Synonyms: Translokacja (11; 14) (q13; q32) (CCND1,IGH) Translokacja (11; 14) (q13; q32) (CCND1,IGH) transkrypt genu fuzyjnego
pt-BR	Portuguese (Brazil)	t(11;14)(q13;q32)(CCND1,IGH )transcrição de fusão::Pt:MedOssea:Ord:Genética molecular
ru-RU	Russian (Russian Federation)	t(11;14)(q13;q32)(CCND1,IGH) слияния транскрипт:PrThr:ТчкВрм:Костный мозг:Пор:МолГен Synonyms: Порядковый Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR	Turkish (Turkey)	t(11;14)(q13;q32)(CCND1,IGH) füzyon transkript:MevcEşik:Zmlı:Kem il:Srl:Molgen Synonyms: Mevcut
zh-CN	Chinese (China)	t(11;14)(q13;q32)(CCND1,IGH) 融合转录物:存在情况或阈值:时间点:骨髓:序数型:分子遗传学类实验室方法 Synonyms: T(11,14)(CLL,IGH) 基因易位;T(11,14)(CLL,IGH) 易位依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录骨骼;骨头髓

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