72380-9
LORazepam [Mass/volume] in Saliva (oral fluid)
Active
Part Descriptions
LP16176-7 LORazepam
Lorazepam (marketed under the brand names Ativan®, Temesta®, Tavor®) is a drug which is a benzodiazepine derivative. Pharmacologically, it is classified as a sedative -hypnotic, anxiolytic and anticonvulsant. Lorazepam reduces anxiety, interferes with new memory formation, reduces agitation, induces sleep, treats seizures, treats nausea and vomiting, and relaxes muscles. Lorazepam is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus, and sedation of hospitalized patients, as well as sedation of aggressive patients. Due to tolerance and dependence, lorazepam is recommended for short-term use, up to two to four weeks only. Among benzodiazepines, lorazepam has possible physical addiction potential. Lorazepam also has misuse potential; the main types of misuse are for recreational purposes.
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Source: Wikipedia, Lorazepam (Wikipedia)
LP16176-7 LORazepam
A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Source: National Library of Medicine, MeSH 2006
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- LORazepam
- Property
- MCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
Additional Names
- Short Name
- LORazepam Sal-mCnc
- Display Name
- LORazepam (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- LORazepam, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 8371
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG37571-3 | Lorazepam| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Lorazepam: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | LORazepam: |
et-EE | Estonian (Estonia) | Lorasepaam: Synonyms: Juhuslik Kvantitatiivne Sülg |
fr-CA | French (Canada) | Lorazépam: Synonyms: #REF! |
fr-FR | French (France) | Lorazépam: |
fr-BE | French (Belgium) | Lorazépam: |
it-IT | Italian (Italy) | Lorazepam: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | lorazepam: |
pt-BR | Portuguese (Brazil) | Lorazepam: |
ru-RU | Russian (Russian Federation) | Лоразепам: Synonyms: Количественный Массовая концентрация Точка во времени; |
tr-TR | Turkish (Turkey) | Lorazepam: |
zh-CN | Chinese (China) | 氯羟安定: Synonyms: 劳拉西泮; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
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