72476-5
Methadone panel - Saliva (oral fluid) by Confirmatory method
Active
72388-2 Methadone [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Part Descriptions
LP15015-8 Methadone
Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon and many other names) is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency. Because it is an acyclic analog of morphine, methadone acts on the same opioid receptors and thus has many of the same effects. Methadone is also used in managing severe chronic pain.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Methadone (Wikipedia)
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Methadone
- Property
- MCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
- Confirm
Additional Names
- Short Name
- Methadone Sal Cfm-mCnc
- Display Name
- Methadone Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- Methadone, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6660
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 72476-5 | Methadone panel - Saliva (oral fluid) by Confirmatory method |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37553-1 | Methadone| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Metadona: |
| es-ES | Spanish (Spain) | Metadona: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Metadoon: Synonyms: Juhuslik Kvantitatiivne Sülg |
| fr-FR | French (France) | Méthadone: |
| fr-BE | French (Belgium) | Méthadone: |
| fr-CA | French (Canada) | Méthadone: |
| it-IT | Italian (Italy) | Metadone: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | methadon: |
| pt-BR | Portuguese (Brazil) | Metadona: |
| ru-RU | Russian (Russian Federation) | Метадон: Synonyms: Количественный Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Metadon: Synonyms: Teyid |
| zh-CN | Chinese (China) | 美沙酮: Synonyms: C21H27NO; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
72387-4 Methadone [Presence] in Saliva (oral fluid) by Confirmatory method
Part Descriptions
LP15015-8 Methadone
Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon and many other names) is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency. Because it is an acyclic analog of morphine, methadone acts on the same opioid receptors and thus has many of the same effects. Methadone is also used in managing severe chronic pain.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Methadone (Wikipedia)
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Methadone
- Property
- PrThr
- Time
- Pt
- System
- Saliva
- Scale
- Ord
- Method
- Confirm
Additional Names
- Short Name
- Methadone Sal Ql Cfm
- Display Name
- Methadone Confirm Ql (Sal)
- Consumer Name Alpha Get Info
- Methadone, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9422
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 72476-5 | Methadone panel - Saliva (oral fluid) by Confirmatory method |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37553-1 | Methadone| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Metadona: |
| es-MX | Spanish (Mexico) | Metadona: |
| et-EE | Estonian (Estonia) | Metadoon: Synonyms: Järgarvuline Juhuslik Sülg |
| fr-FR | French (France) | Méthadone: |
| fr-BE | French (Belgium) | Méthadone: |
| fr-CA | French (Canada) | Méthadone: |
| it-IT | Italian (Italy) | Metadone: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | methadon: |
| pt-BR | Portuguese (Brazil) | Metadona: |
| ru-RU | Russian (Russian Federation) | Метадон: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | Metadon: Synonyms: Mevcut Teyid |
| zh-CN | Chinese (China) | 美沙酮: Synonyms: C21H27NO; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
72385-8 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP) [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Part Descriptions
LP35885-0 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
EDDP (2-ethylidene-1,5-dimethyl1-3,3-diphenylpyrrolidine) is a primary metabolite of methadone, a synthetic opioid used for the treatment of opioid dependence. It is excreted in bile and urine along with other another methadone metabolite, EMPD. Levels of methadone itself are variable and depend on a patient's urine pH value, dose given, and metabolism. EDDP levels are less variable and can be detected 4 to 6 hours after methadone use, therefore, EDDP is preferentially used to check for methadone exposure.
Source: Regenstrief Institute
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
- Property
- MCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
- Confirm
Additional Names
- Short Name
- EDDP Sal Cfm-mCnc
- Display Name
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP) Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP), Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9591
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 72476-5 | Methadone panel - Saliva (oral fluid) by Confirmatory method |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37661-2 | 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | 2-etilideno-1,5-dimetil-3,3-difenilpirrolidina (EDDP): Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 2-etiliden-1,5-dimetil-3,3-difenilpirrolidina: |
| et-EE | Estonian (Estonia) | 2-etüülideen-1,5-dimetüül-3,3-difenüülpürolidiin: Synonyms: Juhuslik Kvantitatiivne Sülg |
| fr-BE | French (Belgium) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP): |
| fr-FR | French (France) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine: |
| fr-CA | French (Canada) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP): |
| it-IT | Italian (Italy) | 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina: Synonyms: 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina (ED Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | 2-ethylideen-1,5-dimethyl-3,3-difenylpyrrolidine: |
| pt-BR | Portuguese (Brazil) | 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidine: |
| ru-RU | Russian (Russian Federation) | 2-Этилиден-1,5-Диметил-3,3-Дифенил Пирролидин: Synonyms: Количественный Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | 2-Etiliden-1,5-Dimetil-3,3-Difenilpirrolidin: Synonyms: Teyid |
| zh-CN | Chinese (China) | 2-亚乙基-1,5-二甲基-3,3-四氢吡咯: Synonyms: Ⅰ 2-乙叉-1,5-二甲基-3,3-吡咯烷; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
72386-6 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP) [Presence] in Saliva (oral fluid) by Confirmatory method
Part Descriptions
LP35885-0 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
EDDP (2-ethylidene-1,5-dimethyl1-3,3-diphenylpyrrolidine) is a primary metabolite of methadone, a synthetic opioid used for the treatment of opioid dependence. It is excreted in bile and urine along with other another methadone metabolite, EMPD. Levels of methadone itself are variable and depend on a patient's urine pH value, dose given, and metabolism. EDDP levels are less variable and can be detected 4 to 6 hours after methadone use, therefore, EDDP is preferentially used to check for methadone exposure.
Source: Regenstrief Institute
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine
- Property
- PrThr
- Time
- Pt
- System
- Saliva
- Scale
- Ord
- Method
- Confirm
Additional Names
- Short Name
- EDDP Sal Ql Cfm
- Display Name
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP) Confirm Ql (Sal)
- Consumer Name Alpha Get Info
- 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine (EDDP), Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9421
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 72476-5 | Methadone panel - Saliva (oral fluid) by Confirmatory method |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37661-2 | 2-Ethylidene-1,5-Dimethyl-3,3-Diphenylpyrrolidine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | 2-etilideno-1,5-dimetil-3,3-difenilpirrolidina (EDDP): |
| es-MX | Spanish (Mexico) | 2-etiliden-1,5-dimetil-3,3-difenilpirrolidina: |
| et-EE | Estonian (Estonia) | 2-etüülideen-1,5-dimetüül-3,3-difenüülpürolidiin: Synonyms: Järgarvuline Juhuslik Sülg |
| fr-FR | French (France) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine: |
| fr-BE | French (Belgium) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP): |
| fr-CA | French (Canada) | 2-éthylidène-1,5-diméthyl-3,3-diphénylpyrrolidine (EDDP): |
| it-IT | Italian (Italy) | 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina: Synonyms: 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidina (ED Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | 2-ethylideen-1,5-dimethyl-3,3-difenylpyrrolidine: |
| pt-BR | Portuguese (Brazil) | 2-Etilidene-1,5-Dimetil-3,3-Difenilpirrolidine: |
| ru-RU | Russian (Russian Federation) | 2-Этилиден-1,5-Диметил-3,3-Дифенил Пирролидин: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | 2-Etiliden-1,5-Dimetil-3,3-Difenilpirrolidin: Synonyms: Mevcut Teyid |
| zh-CN | Chinese (China) | 2-亚乙基-1,5-二甲基-3,3-四氢吡咯: Synonyms: Ⅰ 2-乙叉-1,5-二甲基-3,3-吡咯烷; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
72475-7 Methadone+Metabolite [Presence] in Saliva (oral fluid) by Confirmatory method
Part Descriptions
LP36029-4 Methadone+Metabolite
Methadone is a narcotic analgesic which is used in the treatment of pain and as a primary treatment of narcotic addiction. Methadone metabolites include 2-ethylidene-1, 5-dimethyl-3,3-diphenylpyrrolidine (EDDP) and 2-ethyl-5-methyl-3,3-diphenylpyrroline (EMDP), both of which are inactive. EDDP is the primary metabolite and is the analyte that is measured with methadone for drug monitoring.
Source: Regenstrief LOINC
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Methadone+Metabolite
- Property
- PrThr
- Time
- Pt
- System
- Saliva
- Scale
- Ord
- Method
- Confirm
Additional Names
- Short Name
- Methadone+metab Sal Ql Cfm
- Display Name
- Methadone+Metabolite Confirm Ql (Sal)
- Consumer Name Alpha Get Info
- Methadone+Metabolite, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 11637
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 72476-5 | Methadone panel - Saliva (oral fluid) by Confirmatory method |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37662-0 | Methadone+Metabolite| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Metadona+metabolito: |
| es-MX | Spanish (Mexico) | Metadona + Metabolito: |
| et-EE | Estonian (Estonia) | Metadoon + metaboliit: Synonyms: Järgarvuline Juhuslik Sülg |
| fr-FR | French (France) | Méthadone+métabolite: |
| fr-BE | French (Belgium) | Méthadone+Métabolite: |
| fr-CA | French (Canada) | Méthadone+Métabolite: |
| it-IT | Italian (Italy) | Metadone+Metabolita: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | methadon + metaboliet: |
| pt-BR | Portuguese (Brazil) | Metadona+Metabólito: |
| ru-RU | Russian (Russian Federation) | Метадон+Метаболиты: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | Metadon+Metabolit: Synonyms: Mevcut Teyid |
| zh-CN | Chinese (China) | 美沙酮+代谢产物: Synonyms: C21H27NO; |
Third Party Copyright
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