Version 2.78

Part Descriptions

LP15014-1   Benzodiazepines
The benzodiazepines are a class of drugs with sedative, hypnotic, anxiolytic, anticonvulsant, amnestic and muscle relaxant properties. They are often used for short-term relief of severe, disabling anxiety or insomnia. Long-term use may lead to tolerance and dependency. They are believed to act on the GABA receptor GABAA, the activation of which dampens higher neuronal activity. They began to be widely prescribed for stress-related ailments in the 1960s and 1970s. Their chemical structure is based upon diazepine and phenyl groups. Common benzodiazepines include diazepam, oxazepam, chlorodiazepam, alprozolam, and temazepam. Source: Regenstrief Institute, Benzodiazepines (Wikipedia)

LP15014-1   Benzodiazepines
A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring. Permitted is any degree of hydrogenation, any substituents and any H-isomer. Source: National Library of Medicine, MeSH 2006

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

Fully-Specified Name

Component
Benzodiazepines
Property
MCnc
Time
Pt
System
Saliva
Scale
Qn
Method
Screen

Additional Names

Long Common Name
Benzodiazepines [Mass/volume] in Saliva (oral fluid) by Screen method
Short Name
Benzodiaz Sal Scn-mCnc
Display Name
Benzodiazepines Screen (Sal) [Mass/Vol]
Consumer Name Alpha Get Info
Benzodiazepines, Saliva

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
17913

Member of these Panels

LOINC Long Common Name
73662-9 Benzodiazepines panel - Saliva (oral fluid) by Screen method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Benzodiazepinas:Concentración de masa:Punto temporal:Saliva:Qn:Cribado toxicológico
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Benzodiazepinas:Concentración de masa:Punto temporal:Saliva:Cuantitativo:Pantalla de toxicología
fr-CA French (Canada) Benzodiazépines:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Dépistage
fr-FR French (France) Benzodiazépines:Masse/Volume:Ponctuel:Salive:Numérique:Dépistage
fr-BE French (Belgium) Benzodiazépines:Concentration de masse:Temps ponctuel:Salivaire:Quantitatif:Dépistage
it-IT Italian (Italy) Benzodiazepine:MCnc:Pt:Saliva:Qn:Screening
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Screening tossicologico
nl-NL Dutch (Netherlands) benzodiazepinen:massa/volume:moment:speeksel:kwantitatief:screening
pt-BR Portuguese (Brazil) Benzodiazepinas::Pt:Saliva:Qn:Triagem
ru-RU Russian (Russian Federation) Бензодиазепины:МассКонц:ТчкВрм:Слюна:Колич:Скрининг
Synonyms: Количественный Массовая концентрация Токсикологический скрининг Точка во времени;Момент
tr-TR Turkish (Turkey) Benzodiazepinler:KütlKons:Zmlı:Tükürük:Kant:Tarama
zh-CN Chinese (China) 苯并二氮:质量浓度:时间点:唾液:定量型:毒理学筛查试验
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 津;津液;涎 筛查 筛查方法;筛查法;筛查试验 筛查试验 筛选试验 苯二氮 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 过筛 过筛试验

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72757-8