Version 2.78

Term Description

A patient's genotype for the UGT2B15 gene is typically reported as *A/*B where A is the allele from one chromosome and B is the allele from the other chromosome. The genotype is determined by the analysis of specific single nucleotide polymorphisms (SNPs) within the gene by various molecular techniques, including PCR and microarray. In some cases, SNP results are analyzed by bioinformatics computer software to determine a patient's overall genotype.
Source: Regenstrief LOINC

Part Description

LP157516-8   UGT2B15 gene
The UGT2B15 gene (UDP glucuronosyltransferase 2 family, polypeptide B15) [HGNC Gene ID:12546] is located on chromosome 4q13. This gene encodes a member of the UDP-glycosyltransferase (UDPGT) family. The UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein displays activity towards several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens. [provided by RefSeq, Oct 2011] [NCBI Gene ID:7366] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component
UGT2B15 gene targeted mutation analysis
Property
Prid
Time
Pt
System
Bld/Tiss
Scale
Nom
Method
Molgen

Additional Names

Long Common Name
UGT2B15 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal
Short Name
UGT2B15 Mut Anl Bld/T
Display Name
UGT2B15 gene targeted mutation analysis Molgen Nom (Bld/Tiss)
Consumer Name Alpha Get Info
UGT2B15 gene targeted mutation analysis, Blood or tissue specimen

Example Answer List: LL2250-0

Source: Regenstrief LOINC
Answer Code Score Answer ID
UGT2B15*1/*1 LA19163-7
UGT2B15*1/*2 LA19164-5
UGT2B15*2/*2 LA19165-2

Basic Attributes

Class
MOLPATH.PHARMG
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.67
Change Reason
Release 2.67: CLASS: Updated to MOLPATH.PHARMG, the more representative LOINC Class for this concept.; SYSTEM: Updated System from "Bld/Tiss/Sal" to "Bld/Tiss" since this System in LOINC encompasses all specimens used for germline nucleic acid testing, including blood, tissue and cells contained in swabs as well as fluids such as saliva.; Previous Releases: Based on LOINC Committee review (June 2016), "targeted" was added to the Component to clarify that this test is looking for a specific set of mutations as described in the LOINC User Guide under the Molecular Genetics section.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) gen UGT2B15 Analisis de mutaciones:Presencia o identidad:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-MX Spanish (Mexico) Análisis de mutación dirigida al gen UGT2B15:Presencia o identidad:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FR French (France) UGT2B15 gène mutation cible trouvée:Identification:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-IT Italian (Italy) UGT2B15, gene analisi di mutazione mirata:Prid:Pt:Sangue/Tess:Nom:Molgen
Synonyms: Farmacogenomica Gene UGT2B15 Genetica molecolare Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) UGT2B15-gen doelgerichte mutatie-analyse:identificator:moment:bloed of weefsel:nominaal:moleculair genetisch onderzoek
Synonyms: molgen targeted
pt-BR Portuguese (Brazil) UGT2B15 gene análise de mutação:Ident:Pt:Sg/Tecido:Nom:Genética molecular
ru-RU Russian (Russian Federation) UGT2B15 ген исследование на мутацию:ПрИд:ТчкВрм:Кр/Тк:Ном:МолГен
Synonyms: Кровь Кровь или Ткань Номинальный;Именной Присутствие или Идентификация Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) UGT2B15 geni Mutasyon analizi:MevcKimlik:Zmlı:Kan/Dk:Snf:Molgen
zh-CN Chinese (China) UGT2B15 基因 突变分析:存在与否或特征标识:时间点:全血/组织:名义型:分子遗传学类实验室方法
Synonyms: 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基因突变分析 存在;存在与否;特征标识;身份;身份标识 尿苷二磷酸葡萄糖醛酸基转移酶 2 家族, 多肽 B15;UDP 葡萄糖醛酸基转移酶 2 家族, 多肽 B15;UGT 2 家族, 多肽 B15;UDP 葡萄糖醛酰基转移酶 2 家族, 多肽 B15;UDP 葡萄糖苷酸基转移酶 2 家族, 多肽 B15;UDP 葡萄糖苷酰转移酶 2 家族, 多肽 B15;UDP glucuronosyltransferase 2 family, polypeptide B15 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

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