735-1
Variant lymphocytes/Leukocytes in Blood by Manual count
Active
Term Description
CLSI (formerly NCCLS) document "Reference Leukocyte Differential Count (Proportional) and Evaluation of Instrumental Methods", 1992, recommend the use of variant lymphocytes rather than atypical or reactive lymphocytes.
Part Descriptions
LP15072-9 Lymphocytes.variant
Variant lymphocytes (also called reactive or atypical) are a type of abnormal lymphocyte found in the peripheral blood. They can be a marker for certain viral illnesses, including infectious mononucleosis, viral hepatitis, CMV, HIV, and rubella, and can also occur as part of a drug reaction to drugs such as phenytoin and para-aminosalicylic acid. [NCBI Books: NBK263]
Source: Regenstrief LOINC
, NCBI Books: NBK263
LP157588-7 Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010)
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | Lymphocyte variants are also called atypical lymphocytes. Some automated counters can report these values. LOINC codes for them can be found in the full LOINC database. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Fully-Specified Name
- Component
- Lymphocytes.variant/Leukocytes
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- Manual count
Additional Names
- Long Common Name
- Variant lymphocytes/Leukocytes in Blood by Manual count
- Short Name
- Variant Lymphs NFr Bld Manual
- Display Name
- Variant lymphocytes/Leukocytes Manual cnt (Bld)
- Consumer Name Alpha Get Info
- Variant lymphocytes/White Blood Cells, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 773
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Atyp.Lymphoz.rel.mi. |
| de-DE | German (Germany) | Lymphozyten.atypisch, vermutlich reaktiv/Leukozyten: Synonyms: Aktivierte Lymphozyten |
| el-GR | Greek (Greece) | Λεμφοκύτταρα.παραλλαγή/Λευκοκύτταρα: Synonyms: NFr Λεμφοκύτταρα Λεμφοκύτταρα.παραλλαγή Λευκοκύτταρα |
| es-AR | Spanish (Argentina) | linfocitos.atípico/100 leucocitos: |
| es-MX | Spanish (Mexico) | Linfocitos variante / 100 leucocitos: |
| es-ES | Spanish (Spain) | Linfocitos atípicos/Leucocitos: Synonyms: Cuantitativo |
| fr-FR | French (France) | Lymphocytes variants/100 leucocytes: |
| fr-CA | French (Canada) | Lymphocytes.variante/Leucocytes: |
| it-IT | Italian (Italy) | Linfociti.varianti/Leucociti: Synonyms: Ematologia (coagulazione) conta differenziale Frazione numerica Linfociti Varianti Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 비정형림프구/100 백혈구: |
| nl-NL | Dutch (Netherlands) | lymfocyten.variant/leukocyten: Synonyms: handmatige methode handmatige telling |
| pl-PL | Polish (Poland) | Limfocyty.atypowe/leukocyty: Synonyms: Leukocyty Limfocyty Limfocyty atypowe Limfocyty atypowe/leukocyty |
| pt-BR | Portuguese (Brazil) | Linfócitos.variáveis/100 leucócitos: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Лимфоциты.вариант/Лейкоциты: Synonyms: Количественный Количество отношение Кровь Точка во времени; |
| tr-TR | Turkish (Turkey) | Lenfositler.varyant/Lökosit: Synonyms: El ile |
| uk-UA | Ukrainian (Ukraine) | Лімфоцити.атипові (реактивні)/100 лейкоцитів: Synonyms: 100WBC; |
| zh-CN | Chinese (China) | 淋巴细胞.异型/白细胞: Synonyms: Leuc; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |
| % | eCHN |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=735-1
LOINC Copyright
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