Version 2.78

Part Description

LP172566-4   Iclaprim
Iclaprim, codenamed AR-100 and RO-48-2622, is a diaminopyrimidine dihydrofolate reductase inhibitor being developed for the treatment of complicated skin and soft tissue infections caused by antibiotic-resistant bacteria. It is structurally related to trimethoprim. In Phase III clinical trials, intravenously-administered iclaprim was found to be as effective as and better tolerated than linezolid in people with skin and soft tissue infections, many caused by methicillin-resistant Staphylococcus aureus (MRSA). In vitro, iclaprim is highly active against MRSA, vancomycin-resistant Staphylococcus aureus (VRSA), strains of Streptococcus pneumoniae resistant to several common antibiotics, and some Gram-negative bacteria. A new drug application for iclaprim was filed with the U.S. Food and Drug Administration in March 2008, and a marketing authorisation application (MAA) was accepted by the European Medicines Agency on August 21, 2008. Phase II clinical trials are being conducted to assess whether iclaprim can be taken by mouth as well as intravenously and whether it is effective for the treatment of hospital-acquired pneumonia. Iclaprim has been granted fast track status by the FDA Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Iclaprim
Property
Susc
Time
Pt
System
Isolate
Scale
OrdQn
Method
MIC

Additional Names

Short Name
Iclaprim Islt MIC
Display Name
Iclaprim MIC [Susc]
Consumer Name Alpha Get Info
Susceptibility to Iclaprim

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.44
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
50545-3 Bacterial susceptibility panel by Minimum inhibitory concentration (MIC)

Member of these Groups Get Info

LOINC Group Group Name
LG41455-3 IclaprimSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Iclaprim:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Minimale Hemmkonzentration (MHK)
es-ES Spanish (Spain) Iclaprim:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (CMI)
es-MX Spanish (Mexico) Iclaprim:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Concentración mínima inhibitoria (MIC)
fr-FR French (France) Iclaprime:Sensibilité:Ponctuel:Isolat:Alphanumérique:CMI
it-IT Italian (Italy) Iclaprim:Susc:Pt:Isolato:OrdQn:MIC
Synonyms: Concentrazione minima inibitoria Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) iclaprim:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:minimaal inhiberende concentratie
Synonyms: MIC
pt-BR Portuguese (Brazil) Iclaprim::Pt:Isolado:OrdQn:MIC
ru-RU Russian (Russian Federation) Иклаприм:Чув:ТчкВрм:Изолят:ПорКол:МИК
Synonyms: Минимальная ингибирующая концентрация (МИК) Порядковый или Количественный Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Iklaprim:Duyr:Zmlı:İzolat:SrlKant:MIC
zh-CN Chinese (China) 艾拉普林:抗生素敏感性:时间点:分离株:定量型或序数型:最小抑菌浓度法
Synonyms: 分离物;分离菌;分离菌株;隔离种群 埃拉普林;CAS 192314-93-5;C19H22N4O3;5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 最低抑制浓度;最低抑制浓度法;最低抑菌浓度;最低抑菌浓度法;最小抑制浓度;最小抑制浓度法;最小抑菌浓度;Minimum Inhibitory Concentration;MIC

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73619-9