Version 2.77

Part Description

LP173634-9   Tissue inhibitor of metalloproteinases 1
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a widely expressed, secreted 28kDa protein. It functions primarily to inhibit members of a large family of metalloproteinases (MPs) and, as a result, is involved in many of the same pathophysiological processes as MPs, e.g. wound healing, ovulation, angiogenesis, and cancer cell metastasis. However, it has also been found that elevated TIMP-1 expression in tumors, e.g. stromal cells, is correlated with accelerated tumor progression and poor prognosis. Source: Regenstrief LOINC, PMID: 16142437

Fully-Specified Name

Component
Tissue inhibitor of metalloproteinases 1
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Short Name
TIMP-1 SerPl IA-mCnc
Display Name
Tissue inhibitor of metalloproteinases 1 IA [Mass/Vol]
Consumer Name Alpha Get Info
Tissue inhibitor of metalloproteinases 1, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.46
Last Updated
Version 2.56
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: TIMP-1
es-ES Spanish (Spain) Inhibidor tisular de metaloproteinasas-1:Concentración de masa:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Inhibidor tisular de metaloproteinasas 1:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
fr-FR French (France) Inhibiteur tissulaire métalloprotéinases 1:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
it-IT Italian (Italy) Tessuto inibitore di metalloproteinasi 1:MCnc:Pt:Siero/Plasma:Qn:IA
Synonyms: Chimica Concentrazione di Massa Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) tissue inhibitor van metalloproteïnasen 1:massa/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: IA
pl-PL Polish (Poland) Tkankowy inhibitor metaloproteinazy 1:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:metoda immunologiczna
pt-BR Portuguese (Brazil) Tecido inibidor de metalloproteinases 1::Pt:Soro/Plas:Qn:Imunoensaio
ru-RU Russian (Russian Federation) Тканевый ингибитор металлопротеиназ 1:МассКонц:ТчкВрм:Сыв/Плаз:Колич:IA
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Metaloproteinazlar doku inhibitörü 1:KütlKons:Zmlı:Ser/Plaz:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 金属蛋白酶组织抑制剂 1:质量浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ⅰ I tissue inhibitor of metalloproteinases;TIMPs;金属蛋白酶组织抑制物-1;金属蛋白酶组织抑制因子-1;tissue inhibitor of metalloproteinase-1,TIMP-1 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抑制因子 抑制物 抑制物质 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74101-7