PDGFR-alpha Ag [Presence] in Tissue by Immune stain
Used in localization of PDGF and detection of neoplasms with elevated expression of PDGFR-alpha.
Source: Regenstrief LOINC
Platelet-derived growth factor receptors (PDGFRs) exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and -beta receptors. PDGF-alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons. Source: LOINC partner 1
- PDGFR-alpha Ag
- Immune stain
- Short Name
- PDGFR-alpha Ag Tiss Ql ImStn
- Display Name
- PDGFR-alpha Ag Immune stain Ql (Tiss)
- Consumer Name Alpha Get Info
- PDGFR-alpha antigen, Tissue
Example Answer List: LL360-9Source: Regenstrief Institute
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
- First Released
- Version 2.46
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
Language Variants Get Info
|es-ES||Spanish (Spain)||Receptor del factor de crecimiento derivado de plaquetas alfa Antígeno:
|es-MX||Spanish (Mexico)||PDGFR-alfa Ag:
|fr-FR||French (France)||PDGFR-alpha antigène:
|it-IT||Italian (Italy)||PDGFR alfa , Ag:
Synonyms: Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto &
|nl-NL||Dutch (Netherlands)||PDGFR-alfa Ag:
|pt-BR||Portuguese (Brazil)||PDGFR-alfa Ag:
|ru-RU||Russian (Russian Federation)||PDGFR-альфа Аг:
Synonyms: Порядковый Ткань и мазки Точка во времени;
|tr-TR||Turkish (Turkey)||PDGFR-alpha Ag:
Synonyms: Antijen Mevcut
|zh-CN||Chinese (China)||PDGFR-alpha 抗原:
Synonyms: Ag PDGFR-α;
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Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright