74261-9
HEDIS 2014 Value Set - Phenytoin Level
Discouraged
14877-5 Phenytoin [Moles/volume] in Serum or Plasma
Part Descriptions
LP14732-9 Phenytoin
An anticonvulsant that is used to treat a wide variety of seizure disorders. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its side effects and interactions with other drugs. [MeSH 2014: Phenytoin]
Source: National Library of Medicine, MeSH 2006, MeSH: Phenytoin
Fully-Specified Name
- Component
- Phenytoin
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Phenytoin SerPl-sCnc
- Display Name
- Phenytoin [Moles/Vol]
- Consumer Name Alpha Get Info
- Phenytoin, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 7115
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG49335-9 | Phenytoin| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Phenytoin: |
| de-AT | German (Austria) | Synonyms: Phenytoin |
| el-GR | Greek (Greece) | Φαινυντοΐνη: |
| es-MX | Spanish (Mexico) | Fenitoína: |
| es-ES | Spanish (Spain) | Fenitoína: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | fenitoína: |
| et-EE | Estonian (Estonia) | Fenütoiin: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Phénytoïne: |
| fr-CA | French (Canada) | Phénytoïne: |
| fr-FR | French (France) | Diphénylhydantoïne: |
| it-IT | Italian (Italy) | Fenitoina: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 페니토인: |
| nl-NL | Dutch (Netherlands) | fenytoïne: |
| pt-BR | Portuguese (Brazil) | Fenitoína: Synonyms: Diphenylhydantoin; |
| ru-RU | Russian (Russian Federation) | Фенитоин: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Fenitoin: |
| zh-CN | Chinese (China) | 苯妥英: Synonyms: C15H12N2O2; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
| umol/L | eCHN |
32109-1 Phenytoin Free [Moles/volume] in Serum or Plasma
Part Descriptions
LP14731-1 Phenytoin.free
Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug.
Source: Regenstrief Institute
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Phenytoin.free
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Phenytoin Free SerPl-sCnc
- Display Name
- Phenytoin Free [Moles/Vol]
- Consumer Name Alpha Get Info
- Free phenytoin, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.07
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG47569-5 | Phenytoin.free| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Phenytoin.frei: |
| es-MX | Spanish (Mexico) | Phenytoin.libre: |
| es-ES | Spanish (Spain) | Fenitoína libre: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | fenitoína.libre: |
| et-EE | Estonian (Estonia) | Fenütoiin.vaba: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Phénytoïne.libre: |
| fr-FR | French (France) | Diphénylhydantoïne libre: |
| fr-CA | French (Canada) | Phénytoïne.libre: |
| it-IT | Italian (Italy) | Fenitoina.libera: Synonyms: Concentrazione di Sostanza Fenitoina Libera Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 유리페니토인: |
| nl-NL | Dutch (Netherlands) | fenytoïne.vrij: |
| pt-BR | Portuguese (Brazil) | Fenitoína.livre: Synonyms: Diphenylhydantoin; |
| ru-RU | Russian (Russian Federation) | Фенитоин.свободный: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Fenitoin.serb: |
| zh-CN | Chinese (China) | 苯妥英.游离型: Synonyms: C15H12N2O2; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
| umol/L | eCHN |
3968-5 Phenytoin [Mass/volume] in Serum or Plasma
Part Descriptions
LP14732-9 Phenytoin
An anticonvulsant that is used to treat a wide variety of seizure disorders. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its side effects and interactions with other drugs. [MeSH 2014: Phenytoin]
Source: National Library of Medicine, MeSH 2006, MeSH: Phenytoin
Fully-Specified Name
- Component
- Phenytoin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Phenytoin SerPl-mCnc
- Display Name
- Phenytoin [Mass/Vol]
- Consumer Name Alpha Get Info
- Phenytoin, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 874
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 104596-2 | Phenytoin and Phenobarbital panel - Serum |
| 34540-5 | Phenytoin free and total panel - Serum or Plasma |
| 55427-9 | Seizure disorder tracking panel |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG49335-9 | Phenytoin| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Phenytoin |
| de-DE | German (Germany) | Phenytoin: |
| el-GR | Greek (Greece) | Φαινυντοΐνη: |
| es-MX | Spanish (Mexico) | Fenitoína: |
| es-ES | Spanish (Spain) | Fenitoína: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | fenitoína: |
| et-EE | Estonian (Estonia) | Fenütoiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Phénytoïne: |
| fr-FR | French (France) | Diphénylhydantoïne: |
| fr-CA | French (Canada) | Phénytoïne: |
| it-IT | Italian (Italy) | Fenitoina: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 페니토인: |
| nl-NL | Dutch (Netherlands) | fenytoïne: |
| pt-BR | Portuguese (Brazil) | Fenitoína: Synonyms: Diphenylhydantoin; |
| ru-RU | Russian (Russian Federation) | Фенитоин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Fenitoin: |
| zh-CN | Chinese (China) | 苯妥英: Synonyms: C15H12N2O2; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
| mcg/mL | REGENSTRIEF |
3969-3 Phenytoin Free [Mass/volume] in Serum or Plasma
Part Descriptions
LP14731-1 Phenytoin.free
Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug.
Source: Regenstrief Institute
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Phenytoin.free
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Phenytoin Free SerPl-mCnc
- Display Name
- Phenytoin Free [Mass/Vol]
- Consumer Name Alpha Get Info
- Free phenytoin, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Change Reason
- Changed Order_Obs from 'Observation Only' to fit the current order use cases.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1466
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 34540-5 | Phenytoin free and total panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG47569-5 | Phenytoin.free| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Phenytoin.frei: |
| es-ES | Spanish (Spain) | Fenitoína libre: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Phenytoin.libre: |
| es-AR | Spanish (Argentina) | fenitoína.libre: |
| et-EE | Estonian (Estonia) | Fenütoiin.vaba: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Phénytoïne.libre: |
| fr-FR | French (France) | Diphénylhydantoïne libre: |
| fr-CA | French (Canada) | Phénytoïne.libre: |
| it-IT | Italian (Italy) | Fenitoina.libera: Synonyms: Concentrazione di Massa Fenitoina Libera Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 유리페니토인: |
| nl-NL | Dutch (Netherlands) | fenytoïne.vrij: |
| pt-BR | Portuguese (Brazil) | Fenitoína.livre: Synonyms: Diphenylhydantoin; |
| ru-RU | Russian (Russian Federation) | Фенитоин.свободный: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Fenitoin.serb: |
| zh-CN | Chinese (China) | 苯妥英.游离型: Synonyms: C15H12N2O2; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
| mcg/mL | REGENSTRIEF |
40460-8 Phenytoin.bound [Mass/volume] in Serum or Plasma
Fully-Specified Name
- Component
- Phenytoin.bound
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Bnd Phenytoin SerPl-mCnc
- Display Name
- Phenytoin.bound [Mass/Vol]
- Consumer Name Alpha Get Info
- Phenytoin.bound, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5742
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Fenitoína.: |
| es-ES | Spanish (Spain) | Fenitoina unida: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Fenütoiin.seotud: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-FR | French (France) | Diphénylhydantoïne liée: |
| it-IT | Italian (Italy) | Fenitoina.legata: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 결합페니토인: |
| nl-NL | Dutch (Netherlands) | fenytoïne.gebonden: |
| pt-BR | Portuguese (Brazil) | Fenitoína.ligada: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Фенитоин.связанный: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Fenitoin.bound: |
| zh-CN | Chinese (China) | 苯妥英.结合型: Synonyms: C15H12N2O2; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
| mcg/mL | REGENSTRIEF |
65361-8 Phenytoin [Moles/volume] corrected for albumin in Serum or Plasma
Part Descriptions
LP14732-9 Phenytoin
An anticonvulsant that is used to treat a wide variety of seizure disorders. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its side effects and interactions with other drugs. [MeSH 2014: Phenytoin]
Source: National Library of Medicine, MeSH 2006, MeSH: Phenytoin
Fully-Specified Name
- Component
- Phenytoin^^corrected for albumin
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Phenytoin Album cor SerPl-sCnc
- Display Name
- Phenytoin corrected for albumin [Moles/Vol]
- Consumer Name Alpha Get Info
- Phenytoin Corrected for Albumin, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.70
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 74234-6 | HEDIS 2014 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Fenitoína^^Corregido en función de la albúmina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Fenitoína ^^ corregida por albúmina: |
| et-EE | Estonian (Estonia) | Fenütoiin^^albumiini järgi kohandatud: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Phénytoïne^^Corrigé pour l'albumine: |
| fr-FR | French (France) | Diphénylhydantoïne corrigée pour l'albumine: |
| fr-CA | French (Canada) | Phénytoïne^^Corrigé pour l'albumine: |
| it-IT | Italian (Italy) | Fenitoina^^corretto per albumina: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | fenytoïne^^gecorrigeerd voor albumine: |
| ru-RU | Russian (Russian Federation) | Фенитоин^^поправленный на альбумин: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Fenitoin^^düzeltilmiş albumine göre: |
| zh-CN | Chinese (China) | 苯妥英^^经过针对白蛋白而校正的: Synonyms: Alb; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |