74858-2

Hepatitis E virus genotypes 1+2+3+4 RNA [Presence] in Serum or Plasma from Donor by NAA with probe detection

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Term Description

An in vitro nucleic acid amplification assay for the direct qualitative detection of hepatitis E virus (HEV) genotypes 1-4 RNA in human plasma or serum. This is a blood screening assay to detect HEV RNA. Plasma from whole blood, blood components, or collections by apheresis can also be used. Plasma from all donors or manufacturing pools may be tested as separate specimens or in pools composed of aliquots of individual specimens. This assay is not meant for use on cord blood nor for use as an aid in diagnosis. This term was created for, but not limited in use to, the Cobas® HEV assay.
Source: Regenstrief LOINC

Part Description

LP183572-9   Hepatitis E virus genotypes 1+2+3+4 RNA
Hepatitis E virus (HEV) is a small, non-enveloped, single-stranded RNA virus. There are four major HEV genotypes (genotypes 1 to 4) that comprise a single serotype. Genotypes 1, 2 and 4 are associated with widespread outbreaks and are found in Asia and Africa, Mexico and west Africa, and Taiwan and China, respectively. Genotype 3 is the cause of isolated cases in developed countries. HEV infection targets the liver and is usually a self-limited, acute illness in immunocompetent patients, however, patients with solid organ transplants who are infected with HEV may develop chronic hepatitis. In developing countries, the most common source of HEV is fecally-contaminated drinking water. In developed countries, sporadic cases of HEV genotype 3 have occurred following consumption of uncooked or undercooked pork or deer meat and consumption of shellfish; zoonotic spread is possible though not common. As of 2015, there is no FDA-approved vaccine for HEV in the U.S., but a recombinant vaccine was recently approved for use in China. [CDC: hepatitis/hev/hevfaq.htm] Source: Regenstrief LOINC, CDC: Hepatitis E Virus

Fully-Specified Name

Component

Hepatitis E virus genotypes 1+2+3+4 RNA

Property

PrThr

Time

Pt

System

Ser/Plas^Donor

Scale

Ord

Method

Probe.amp.tar

Additional Names

Long Common Name

Hepatitis E virus genotypes 1+2+3+4 RNA [Presence] in Serum or Plasma from Donor by NAA with probe detection

Short Name

HEV 1+2+3+4 RNA SerPl Donr Ql NAA+probe

Display Name

HEV genotypes 1+2+3+4 RNA NAA+probe Ql (S/P donor)

Consumer Name Alpha Get Info

HEV genotypes 1+2+3+4, Donor Blood

Example Answer List: LL2888-7

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.48

Last Updated

Version 2.63

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Language Variants Get Info

Related Names

• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• DNA NUCLEIC ACID PROBE
• DNA probe
• Donr
• Hep
• Hep E
• Hepatis
• Hepatit
• Hepatology
• HEV
• HEV 1+2+3+4
• HEV 1-4 RNA
• i
• ID
• II
• III
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Liver
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Ordinal
• PCR
• Pl
• Plasma
• Plsm
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Ribonucleic acid
• Screen
• SDA
• SerP
• SerPl
• SerPlas
• Serum
• Serum or plasma
• SR
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.