Version 2.74

Term Description

An in vitro nucleic acid amplification assay for the direct qualitative detection of hepatitis E virus (HEV) genotypes 1-4 RNA in human plasma or serum. This is a blood screening assay to detect HEV RNA. Plasma from whole blood, blood components, or collections by apheresis can also be used. Plasma from all donors or manufacturing pools may be tested as separate specimens or in pools composed of aliquots of individual specimens. This assay is not meant for use on cord blood nor for use as an aid in diagnosis. This term was created for, but not limited in use to, the Cobas® HEV assay.
Source: Regenstrief LOINC

Part Description

LP183572-9   Hepatitis E virus genotypes 1+2+3+4 RNA
Hepatitis E virus (HEV) is a small, non-enveloped, single-stranded RNA virus. There are four major HEV genotypes (genotypes 1 to 4) that comprise a single serotype. Genotypes 1, 2 and 4 are associated with widespread outbreaks and are found in Asia and Africa, Mexico and west Africa, and Taiwan and China, respectively. Genotype 3 is the cause of isolated cases in developed countries. HEV infection targets the liver and is usually a self-limited, acute illness in immunocompetent patients, however, patients with solid organ transplants who are infected with HEV may develop chronic hepatitis. In developing countries, the most common source of HEV is fecally-contaminated drinking water. In developed countries, sporadic cases of HEV genotype 3 have occurred following consumption of uncooked or undercooked pork or deer meat and consumption of shellfish; zoonotic spread is possible though not common. As of 2015, there is no FDA-approved vaccine for HEV in the U.S., but a recombinant vaccine was recently approved for use in China. [CDC: hepatitis/hev/hevfaq.htm] Source: Regenstrief LOINC, CDC: Hepatitis E Virus

Fully-Specified Name

Hepatitis E virus genotypes 1+2+3+4 RNA

Additional Names

Short Name
HEV 1+2+3+4 RNA SerPl Donr Ql NAA+probe
Display Name
HEV genotypes 1+2+3+4 RNA NAA+probe Ql (S/P donor)
Consumer Name Alpha Get Info
HEV genotypes 1+2+3+4, Donor Blood

Example Answer List: LL2888-7

Source: Roche Diagnostics International
Answer Code Score Answer ID
NonreactiveCopyright ID:131194007 Non-reactive (qualifier value) LA15256-3
ReactiveCopyright ID:11214006 Reactive (qualifier value) LA15255-5
InvalidCopyright ID:455371000124106 Invalid result (qualifier value) LA15841-2

Basic Attributes

First Released
Version 2.48
Last Updated
Version 2.63
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-E-Virus Genotypen 1+2+3+4 RNA:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma^Donor:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Virus de la hepatitis E genotipos 1+2+3+4 RNA:PrThr:Punto temporal:Suero o Plasma^donante:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Genotipos 1 + 2 + 3 + 4 del virus de la hepatitis E ARN:Presencia o umbral:Punto temporal:Suero o plasma ^ Donante:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Hépatite E virus ARN génotypes 1+2+3+4:Présence/Seuil:Ponctuel:Sérum/Plasma du donneur:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Epatite E virus, genotipi 1+2+3+4 RNA:PrThr:Pt:Siero/Plasma^donatore:Ord:Sonda.amp.tar
Synonyms: Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite E
nl-NL Dutch (Netherlands) Hepatitis E-virus genotypes 1+2+3+4 RNA:aanwezigheid:moment:serum of plasma^donor:ordinaal:moleculaire techniek (PCR)
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Hepatite E vírus genótipos 1+2+3+4 RNA::Pt:Soro/Plas^doador:Ord:Sonda com limite de detecção da amplificação de alvo
ru-RU Russian (Russian Federation) Гепатит E вирус генотипы 1+2+3+4 РНК:PrThr:ТчкВрм:Сыв/Плаз^донор:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Плазма Порядковый Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatitis E virüs genotypes 1+2+3+4 RNA:MevcEşik:Zmlı:Ser/Plaz^verici:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 戊型肝炎病毒基因型 1+2+3+4 RNA:存在情况或阈值:时间点:血清/血浆^供体:序数型:探针法.基因扩增.靶向
Synonyms: Ⅰ Ⅱ Ⅲ E 型 Hep E;HEV;戊型肝炎;戊肝;戊肝病毒;肝炎病毒 E 型 I II III 三 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 供血者;捐献者;捐赠者;给予体;给体;超系统 - 供体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 戊肝病毒基因型 1+2+3+4;肝炎病毒 E 型基因型 1+2+3+4 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 经过扩增的 肝 脱氧核糖核酸探针 血清/血浆^捐赠者 血清或血浆

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