Version 2.78

Part Descriptions

LP14729-5   PHENobarbital
Phenobarbital is an antiepileptic drug first introduced for clinical use in 1912. It is still used to treat most seizures except for absence seizure types. The CYP2C19 enzyme metabolizes phenobarbital to p-hydroxyphenobarbital which is then excreted as glucuronide. Phenobarbital induces secretion of liver enzymes which can impact the efficacy of drugs administered at the same time. The most common side effect of phenobarbital in adults with blood levels greater than 40 mg/L is sedation. Phenobarbital is an active metabolite of primidone and so must also be monitored in patients on primidone.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns) Source: Regenstrief LOINC

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
PHENobarbital^trough
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
PHENobarbital [Mass/volume] in Serum or Plasma --trough
Short Name
Phenobarb Trough SerPl-mCnc
Display Name
PHENobarbital trough [Mass/Vol]
Consumer Name Alpha Get Info
PHENobarbital trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.48
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
78436-3 Primidone and PHENobarbital trough panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Φαινοβαρβιτάλη^κατώτερα επίπεδα:Συγκέντρωση μάζας:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:
es-ES Spanish (Spain) Fenobarbital^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Fenobarbital ^ canal:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Fenobarbitaal^baas:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Phénobarbital^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Phénobarbital taux résiduel:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Phénobarbital^Creux:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Minimum, nadir
it-IT Italian (Italy) Fenobarbital^valore minimo:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NL Dutch (Netherlands) fenobarbital^dalspiegel:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Fenobarbital^basal::Pt:Soro/Plas:Qn:
ru-RU Russian (Russian Federation) Фенобарбитал^остаточная концентрация:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Fenobarbital^en düşük:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CN Chinese (China) 苯巴比妥^波谷:质量浓度:时间点:血清/血浆:定量型:
Synonyms: C12H12N2O3;苯巴比妥米那;鲁米那;苯基巴比妥;本巴比妥 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆

Example Units

Unit Source
mg/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74926-7