Version 2.80

Part Description

LP32949-7   Lymphocyte proliferation
Ojo-Amaize, EA Lymphocyte Mitogen Stimulation. Lymphocyte mitogen stimulation assays are used for in vitro assessment of cellular immunity in patients with immunodeficiency, autoimmunity, infectious diseases, cancer and chemical-induced hypersensitivity reactions. Lymphocytes from healthy human subjects have receptors for mitogens such as the plant lectin concanavalin A (UCon A), pokeweed mitogen (PWM), the protein A component of Staphylococcus aureus Cowan strain I (SpA) and chemicals. Lymphocytes respond to these mitogens (substances that stimulate large numbers of lymphocytes without prior sensitization and in contrast to antigens do not require a sensitized host). Both B cells and T cells can be stimulated with mitogens. Inability of lymphocytes to respond to mitogens is a sign of impaired cell-mediated or humoral immunity.

There is a good correlation between CD4+ T-cell subset numbers and mitogenic response to PWM at different disease states in patients with HIV infection. [3H]-thymidine uptake is the gold standard for measuring lymphocyte mitogen stimulation.

However, a newer and more practical method utilizing supravital stains shows a good correlation with [3H]-thymidine uptake. Flow cytometry was also recently applied to analyze proliferation of cultured cells in response to stimulation with mitogen. Copyright Copyright © 1996 - 2008 Specialty Laboratories Source: Specialty Laboratories , Lymphocyte proliferation

Fully-Specified Name

Component
Lymphocyte proliferation
Property
Imp
Time
Pt
System
Bld
Scale
Nar
Method

Additional Names

Long Common Name
Lymphocyte proliferation [Interpretation] in Blood Narrative
Short Name
Lymphocyte prolif Bld-Imp Nar
Display Name
Lymphocyte proliferation Nar (Bld) [Interp]
Consumer Name Alpha Get Info
Interpretation of Lymphocyte proliferation test result, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.50 (MIN)
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC Group Group Name
LG21870-7 Lymphocyte proliferation|Imp|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Πολλαπλασιασμός λεμφοκυττάρων:Imp:Pt:Αίμα:Nar:
Synonyms: Imp Λεμφοκύτταρο Πολλαπλασιασμός λεμφοκυττάρων
es-ES Spanish (Spain) Proliferación de linfocitos:Impresión/interpretación del estudio:Punto temporal:Sangre:Narrativo:
es-MX Spanish (Mexico) Proliferación de linfocitos:Impresión / interpretación del estudio:Punto temporal:Sangre:Narrativo:
fr-CA French (Canada) Prolifération des lymphocytes:Impression:Temps ponctuel:Sang:Narratif:
fr-FR French (France) Lymphocytes prolifération:Interprétation:Ponctuel:Sang:Résultat textuel:
fr-BE French (Belgium) Prolifération des lymphocytes:Impression/interprétation d'étude:Temps ponctuel:Sang:Narratif:
it-IT Italian (Italy) Linfociti, proliferazione:Imp:Pt:Sangue:Nar:
Synonyms: Impressione/interpretazione di studio Proliferazione dei linfociti Punto nel tempo (episodio) Sangue Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) lymfocytenproliferatie:interpretatie:moment:bloed:tekstueel:
pt-BR Portuguese (Brazil) Proliferação de linfócitos::Pt:SgTotal:Nar:
ru-RU Russian (Russian Federation) Лимфоцит пролиферация:Впчт:ТчкВрм:Кр:Опис:
Synonyms: Впечатление/интерпретация исследования Кровь Описательный Точка во времени;Момент
tr-TR Turkish (Turkey) Lenfosit proliferasyonu:İzlnm:Zmlı:Kan:Öykü:
zh-CN Chinese (China) 淋巴细胞增殖:印象:时间点:全血:叙述型:
Synonyms: LAP LAST LPA LPT LST PHA PHA 淋巴细胞转化试验 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 时刻;随机;随意;瞬间 植物血凝素 植物血凝素（phytohaemagglutinin，phytohemagglutinin，PHA） 淋巴细胞刺激试验 淋巴细胞刺激试验（Lymphocyte stimulation test，LST） 淋巴细胞增殖（Lymphocyte proliferation） 淋巴细胞增殖试验 淋巴细胞增殖试验（Lymphocyte proliferation test，LPT） 淋巴细胞抗原刺激试验 淋巴细胞抗原刺激试验（Lymphocyte antigen stimulation test，LAST） 淋巴细胞抗原增殖 淋巴细胞抗原增殖（Lymphocyte antigen proliferation，LAP） 淋巴细胞转化试验 淋巴细胞转化试验（lymphocyte proliferation assay，LPA，淋转） 淋转 血;血液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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CodeSystem lookup
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