75664-3

Human papilloma virus 16 DNA [Presence] in Anorectal specimen by Probe and signal amplification method

Active

Term Description

Men who are at high risk for sexually transmitted diseases for HPV-related anal cancer may be tested similar to a cervical Pap smear where the anal lining is swabbed and cells examined microscopically. HPV DNA tests can also be performed on these samples and similarly, positive results need to be followed up with further testing, including a more thorough exam and possible biopsy. HPV type 16 and 18 are the most common carcinogenic HPV types, with HPV type 16 as the greatest risk for HPV persistence, along with other risk factors of increasing age, smoking, immunosuppression, inflammation, hormones and genetic factors. This term was created for, but not limited in use to, the cobas HPV test kit which uses PCR and nucleic acid hybridization for the detection of 14 high-risk (HR) HPV types.

Part Description

LP18037-9 Human papilloma virus 16
HPV type 16 has been associated with low grade cervical abnormalities, cancer precursors, and anogenital cancers. Type 16 is the cause of approximately 50% of cervical cancers worldwide, HPV types 16 and 18 together account for about 70% of cervical cancers. Source: Centers for Disease Control and Prevention , Human papilloma virus 16

Fully-Specified Name

Component: Human papilloma virus 16 DNA
Property: PrThr
Time: Pt
System: Anorectal
Scale: Ord
Method: Probe.amp.sig

Additional Names

Long Common Name: Human papilloma virus 16 DNA [Presence] in Anorectal specimen by Probe and signal amplification method
Short Name: HPV16 DNA Anorectl Ql Probe+sig amp
Display Name: HPV 16 DNA Probe+sig amp Ql (Anorectal)
Consumer Name Alpha Get Info: HPV 16, Anorectal

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.50
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 11309

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ιός ανθρώπινων θηλωμάτων 16 DNA:PrThr:Pt:Ορθοπρωκτικό:Ord:Ανιχνευτής.ενίσχυση.σήματος Synonyms: DNA PrThr Ιός Ιός ανθρώπινων θηλωμάτων Ιός ανθρώπινων θηλωμάτων 16
es-ES	Spanish (Spain)	Papilomavirus humano 16 ADN:PrThr:Punto temporal:Anorectal:Ord:Sonda con amplificación de señal
es-MX	Spanish (Mexico)	ADN del virus del papiloma humano 16:Presencia o umbral:Punto temporal:Anorrectal:Ordinal:Sonda con amplificación de señal
fr-CA	French (Canada)	Papillomavirus humain 16, ADN:Présence-Seuil:Temps ponctuel:Anorectal:Ordinal:Sonde avec amplification du signal
fr-FR	French (France)	Papillomavirus humain 16 ADN:Présence/Seuil:Ponctuel:Anorectal:Qualitatif:PCR amplification du signal
it-IT	Italian (Italy)	Papilloma virus umano 16 DNA:PrThr:Pt:Anorettale:Ord:Sonda.amp.sig Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del segnale Sonda di DNA
nl-NL	Dutch (Netherlands)	Humaan papillomavirus 16 DNA:aanwezigheid:moment:anorectaal:ordinaal:probe.amp.sig
tr-TR	Turkish (Turkey)	Human papilloma virüsü 16 DNA:MevcEşik:Zmlı:Anorektal:Srl:Prob.amf.siny Synonyms: Mevcut
zh-CN	Chinese (China)	人乳头瘤病毒 16 型 DNA:存在情况或阈值:时间点:肛门直肠:序数型:探针法.基因扩增.信号 Synonyms: HPV 16;HPV 16 型;HPV16;人类乳头瘤病毒 16 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV;人乳头瘤病毒（Human papilloma virus，HPV）;人类乳头瘤病毒;生殖器疣传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助信号扩增的探针方法;借助信号扩增的探针法;探针法.扩增.信号;支链 DNA;支链 DNA（Branched Chain DNA，bDNA）;杂交保护分析;杂交保护分析（Hybidization Protection Assay，HPA）;杂交保护测定;杂种捕获;杂种捕获（Hybrid Capture）;杂种捕获核酸杂交（Hybrid Capture nucleic acid hybridization）借助扩增的探针方法;借助扩增的探针法;探针法.扩增去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间经过扩增的肛肠脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75664-3

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

LOINC Copyright

Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.