75858-1
Sterols panel [Mass/volume] - Serum or Plasma
Active
75739-3 Desmosterol [Mass/volume] in Serum or Plasma
Part Descriptions
LP173717-2 Desmosterol
Desmosterol is an intermediate in the synthesis of cholesterol. Desmosterolosis is a rare autosomal recessive inborn errors of cholesterol synthesis that is caused by defective activity of desmosterol reductase which results in an accumulation of demosterol (DHCR24, EC 1.3.1.72), combines a severe osteosclerotic skeletal dysplasia and includes 2-3 toe syndactyly with Smith-Lemli-Opitz syndrome (SLOS; the biochemical block in SLOS results in decreased cholesterol levels and increased 7-dehydrocholesterol levels). Desmosterolosis is caused by mutation of the 24-dehydrocholesterol reductase gene (DHCR24). Many of the malformations in SLOS and desmosterolosis are consistent with impaired hedgehog function. The hedgehog proteins include Sonic hedgehog (SHH), which plays a major role in midline patterning and limb development. Desmosterolosis, caused by defective activity of desmosterol reductase, combines a severe osteosclerotic skeletal dysplasia. 7-dehydrocholesterol reductase (DHCR7, EC 1.3.1.21) reduces the C7-C8 double bond in the sterol B ring to form cholesterol or desmosterol depending upon the precursor. Desmosterol can be converted to cholesterol by DHCR24. Therefore, SLOS and Desmosterolosis patients invariably have elevated levels of cholesterol precursor's 7-dehydrocholesterol (and its spontaneous isomer 8-dehydrocholesterol) and absent desmosterol. PMID: 14631207, PMID: 16207203.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, HMDB: 02719
Fully-Specified Name
- Component
- Desmosterol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 17551
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG43385-0 | Desmosterol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Δεσμοστερόλη: Synonyms: MCnc Δεσμοστερόλη |
| es-MX | Spanish (Mexico) | Desmosterol: |
| es-ES | Spanish (Spain) | Desmosterol: Synonyms: Cuantitativo |
| fr-FR | French (France) | Desmostérol: |
| fr-CA | French (Canada) | Desmostérol: |
| it-IT | Italian (Italy) | Desmosterolo: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | desmosterol: |
| ru-RU | Russian (Russian Federation) | Десмостерол: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Dezmosterol: |
| zh-CN | Chinese (China) | 链甾醇: Synonyms: 24-脱氢胆固醇; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
75740-1 Lathosterol [Mass/volume] in Serum or Plasma
Part Descriptions
LP185931-5 Lathosterol
Lathosterol is a sterol and lipid found in the cell membranes of all body tissues, and transported in the blood plasma of all animals. It is used as an indicator of whole-body cholesterol synthesis PMID: 14511438. Plasma lathosterol levels are significantly elevated in patients with bile acid malabsorption PMID: 8777839.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
, Lathosterol
Fully-Specified Name
- Component
- Lathosterol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 18647
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG45386-6 | Lathosterol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Λαθοστερόλη: Synonyms: MCnc Λαθοστερόλη |
| es-ES | Spanish (Spain) | Latosterol: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Lathosterol: |
| fr-CA | French (Canada) | Lathostérol: |
| fr-FR | French (France) | Lathostérol: |
| it-IT | Italian (Italy) | Lathosterolo: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | lathosterol: |
| tr-TR | Turkish (Turkey) | Latosterol: |
| zh-CN | Chinese (China) | 7-烯胆甾烷醇: Synonyms: 7-烯胆烷醇; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
75738-5 Campesterol [Mass/volume] in Serum or Plasma
Part Descriptions
LP99350-8 Campesterol
Campesterol is a phytosterol, meaning it is a steroid derived from plants. As a food additive, phytosterols have cholesterol-lowering properties (reducing cholesterol absorption in intestines), and may act in cancer prevention. Phytosterols naturally occur in small amount in vegetable oils, especially soybean oil. One such phytosterol complex, isolated from vegetable oil, is cholestatin, composed of campesterol, stigmasterol, and brassicasterol, and is marketed as a dietary supplement. Sterols can reduce cholesterol in human subjects by up to 15%. The mechanism behind phytosterols and the lowering of cholesterol occurs as follows : the incorporation of cholesterol into micelles in the gastrointestinal tract is inhibited, decreasing the overall amount of cholesterol absorbed. This may in turn help to control body total cholesterol levels, as well as modify HDL, LDL and TAG levels. Many margarines, butters, breakfast cereals and spreads are now enriched with phytosterols and marketed towards people with high cholesterol and a wish to lower it.
[HMDB ID: HMDB02869]
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
LP99350-8 Campesterol
Phytosterols (e.g., β-sitosterol, campesterol, stigmasterol, and brassicasterol) are common components of plant foods,such as vegetable oils, seeds, and nuts. An average Western diet contains approx. 200-400 mg of phytosterols per day. Phytosterols are structurally similar to cholesterol and differ only in the number of carbons or double bonds in the side chain. Since serum and tissue phytosterols are derived from intestinal absorption, levels reflect dietary plant sterol intake and intestinal absorption. Markedly increased serum phytosterol concentrations (e.g., β-sitosterol > 50 mg/l) is seen in sitosterolemia, a rare autosomal recessive lipid disorder. These patients develop premature coronary heart disease. A study suggests that even slightly increased campesterol (3.8 ± 1.6 mg/l) and β-sitosterol (3.1 ± 1.1 mg/l) concentrations in serum may contribute to the risk of coronary heart disease. PMID: 15489546
Source: Regenstrief LOINC
, PMID:15489546
Fully-Specified Name
- Component
- Campesterol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 17733
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG48236-0 | Campesterol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Καμπεστερόλη: Synonyms: MCnc Καμπεστερόλη |
| es-MX | Spanish (Mexico) | Campesterol: |
| es-ES | Spanish (Spain) | Campesterol: Synonyms: Cuantitativo |
| fr-BE | French (Belgium) | Campestérol: |
| fr-CA | French (Canada) | Campestérol: |
| fr-FR | French (France) | Campestérol: |
| it-IT | Italian (Italy) | Campesterolo: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | campesterol: |
| ru-RU | Russian (Russian Federation) | Кампестерол: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Campesterol: |
| zh-CN | Chinese (China) | 菜油固醇: Synonyms: 化学; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
75741-9 Beta sitosterol [Mass/volume] in Serum or Plasma
Part Descriptions
LP173720-6 Beta sitosterol
β-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol. Alone and in combination with similar phytosterols, β-sitosterol reduces blood levels of cholesterol, and is sometimes used in treating hypercholesterolemia. β-sitosterol inhibits cholesterol absorption in the intestine, reducing the levels of LDL and total serum cholesterol. β-Sitosterol is not recommended for individuals with sitosterolemia, a rare inherited fat storage disease. Because people with this condition have too much β-sitosterol and related fats in their system, taking β-sitosterol will only worsen this condition. High levels of β-sitosterol concentrations in blood have been correlated with increased severity of heart disease in men having previously suffered from heart attacks.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Beta Sitosterol
Fully-Specified Name
- Component
- Beta sitosterol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.50
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 11570
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG43208-4 | Beta sitosterol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | β-σιτοστερόλη: Synonyms: MCnc β-σιτοστερόλη |
| es-ES | Spanish (Spain) | Beta-sitosterol: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Beta sitosterol: |
| fr-FR | French (France) | Bêta sitostérol: |
| fr-CA | French (Canada) | Bêta sitostérol: |
| it-IT | Italian (Italy) | Beta sitosterolo: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | bèta-sitosterol: Synonyms: Beta-sitosterol |
| ru-RU | Russian (Russian Federation) | Бета ситостерол: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Beta sitosterol: |
| zh-CN | Chinese (China) | Beta 谷甾醇: Synonyms: B Beta 谷固醇; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
100427-4 Stigmasterol [Mass/volume] in Serum or Plasma
Part Descriptions
LP173719-8 Stigmasterol
Stigmasterol is a phytosterol, meaning it is steroid derived from plants. As a food additive, phytosterols have cholesterol-lowering properties (reducing cholesterol absorption in intestines), and may act in cancer prevention. Phytosterols naturally occur in small amount in vegetable oils, especially soybean oil. One such phytosterol complex, isolated from vegetable oil, is cholestatin, composed of campesterol, stigmasterol, and brassicasterol, and is marketed as a dietary supplement. Sterols can reduce cholesterol in human subjects by up to 15%. The mechanism behind phytosterols and the lowering of cholesterol occurs as follows : the incorporation of cholesterol into micelles in the gastrointestinal tract is inhibited, decreasing the overall amount of cholesterol absorbed. This may in turn help to control body total cholesterol levels, as well as modify HDL, LDL and TAG levels. Many margarines, butters, breakfast cereals and spreads are now enriched with phytosterols and marketed towards people with high cholesterol and a wish to lower it.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Stigmasterol
LP173719-8 Stigmasterol
Phytosterols (e.g., β-sitosterol, campesterol, stigmasterol, and brassicasterol) are common components of plant foods,such as vegetable oils, seeds, and nuts. An average Western diet contains approx. 200-400 mg of phytosterols per day. Phytosterols are structurally similar to cholesterol and differ only in the number of carbons or double bonds in the side chain. Since serum and tissue phytosterols are derived from intestinal absorption, levels reflect dietary plant sterol intake and intestinal absorption. Markedly increased serum phytosterol concentrations (e.g., β-sitosterol > 50 mg/l) is seen in sitosterolemia, a rare autosomal recessive lipid disorder. These patients develop premature coronary heart disease. A study suggests that even slightly increased campesterol (3.8 ± 1.6 mg/l) and β-sitosterol (3.1 ± 1.1 mg/l) concentrations in serum may contribute to the risk of coronary heart disease. PMID: 15489546
Source: Regenstrief LOINC
, PMID:15489546
Fully-Specified Name
- Component
- Stigmasterol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.73
- Last Updated
- Version 2.73 (ADD)
- Order vs. Observation
- Both
Formula (Readable)
< or = 0.5 mg/L
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51388-3 | Stigmasterol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Στιγμαστερόλη: Synonyms: MCnc |
| es-ES | Spanish (Spain) | Estigmasterol: Synonyms: Cuantitativo |
| fr-FR | French (France) | Stigmastérol: |
| it-IT | Italian (Italy) | Stigmasterolo: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | stigmasterol: |
| pl-PL | Polish (Poland) | Stygmasterol: Synonyms: Stygmasterol |
| ru-RU | Russian (Russian Federation) | Стигмастерол: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Stigmasterol: |
| zh-CN | Chinese (China) | 豆甾醇: Synonyms: 化学; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
100426-6 Squalene [Mass/volume] in Serum or Plasma
Part Descriptions
LP200440-8 Squalene
Squalene is a naturally occurring polyprenyl compound and an intermediate metabolite in the synthesis of cholesterol. Serum squalene originates from endogenous cholesterol synthesis and from dietary sources. PMID: 9988781 One study found that women with elevated ratios of serum squalene, campesterol and sitosterol to cholesterol and low respective lathosterol values have enhanced risk for coronary artery disease (CAD). PMID: 10758959
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Squalene
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.73
- Last Updated
- Version 2.73 (ADD)
- Order vs. Observation
- Both
Formula (Readable)
< or = 1.0 mg/L
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51387-5 | Squalene| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Σκουαλένιο: Synonyms: MCnc |
| es-ES | Spanish (Spain) | Escualeno: Synonyms: Cuantitativo |
| fr-FR | French (France) | Squalène: |
| it-IT | Italian (Italy) | Squalene: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| tr-TR | Turkish (Turkey) | Skualen: |
| zh-CN | Chinese (China) | 角鲨烯: Synonyms: 化学; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
100425-8 DiHydro T-Mas [Mass/volume] in Serum or Plasma
Fully-Specified Name
- Component
- DiHydro T-Mas
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.73
- Last Updated
- Version 2.73 (ADD)
- Order vs. Observation
- Both
Formula (Readable)
< or = 0.3 mg/L
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | DiHydro T-Mas: Synonyms: MCnc |
| es-ES | Spanish (Spain) | Dihydro T-Mas: Synonyms: Cuantitativo |
| fr-FR | French (France) | Dihydro T-Mas: |
| it-IT | Italian (Italy) | DiHydro T-Mas: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | DiHydro T-Mas: |
| zh-CN | Chinese (China) | 二氢 T-MAS: Synonyms: 二氢睾丸减数分裂激活固醇; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |
100424-1 8(9)-Cholestenol [Mass/volume] in Serum or Plasma
Part Descriptions
LP186173-3 8(9)-Cholestenol
8(9)-Cholestenol is one of the precursors to cholesterol in the cholesterol biosynthetic pathway. Elevation of 8(9)-cholestenol is the primary marker for X-linked dominant chondrodysplasia punctata 2 (CDPX2), also known as Conradi Hunermann Happle syndrome, a rare disorder associated with abnormal punctate calcification of cartilaginous structures in an asymmetric pattern, scoliosis, congenital hip dislocation, skeletal disease, and characteristic skin lesions. The disorder is usually lethal in affected males and has variable manifestations in affected females. CDPX2 is caused by a mutation in the EDP gene, which encodes cholestenol delta-isomerase, the enzyme that metabolizes 8(9)-cholestenol. PMID: 23798009
Source: Regenstrief LOINC
, PMID: 23798009
Fully-Specified Name
- Component
- 8(9)-Cholestenol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.73
- Last Updated
- Version 2.73 (ADD)
- Order vs. Observation
- Both
Formula (Readable)
< or = 5.0 mg/L
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 75858-1 | Sterols panel [Mass/volume] - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51389-1 | 8(9)-Cholestenol| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | 8(9)-Χοληστενόλη: Synonyms: MCnc |
| es-ES | Spanish (Spain) | 8(9)-Colestenol: Synonyms: Cuantitativo |
| fr-FR | French (France) | 8(9)-cholesténol: |
| it-IT | Italian (Italy) | 8(9) Colestenolo: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | 8(9)-cholestenol: |
| pl-PL | Polish (Poland) | 8(9)-cholestenol: |
| tr-TR | Turkish (Turkey) | 8(9)-kolestenol: |
| zh-CN | Chinese (China) | 8(9)-胆甾烯醇: Synonyms: 8(9)-胆甾醇烯醇 化学; |
Example Units
| Unit | Source |
|---|---|
| mg/L | Example UCUM Units |