76078-5

Influenza virus A RNA [Presence] in Nasopharynx by NAA with probe detection

Active

Part Description

LP14239-5 Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Influenza virus A RNA:PrThr:Pt:Nph:Ord:Probe.amp.tar
Long Common Name: Influenza virus A RNA [Presence] in Nasopharynx by NAA with probe detection
Short Name: FLUAV RNA Nph Ql NAA+probe
Display Name: FLUAV RNA NAA+probe Ql (Nph)
Consumer Name Alpha Get Info: Influenza A (Flu A), Nasopharynx

Part Model Get Info

Component
Influenza virus A RNA
LP38646-3
- Analyte
  Influenza virus A RNA
  LP38646-3
  - Component Numerator
    Influenza virus A RNA
    LP38646-3
    - Component Numerator Core
      Influenza virus A
      LP14239-5
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Nph
LP30875-6
- System Core
  Nph
  LP30875-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.50
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 989

Member of these Panels

LOINC	Long Common Name
77029-7	Respiratory pathogens DNA and RNA 14 panel - Nasopharynx by NAA with probe detection
76091-8	Respiratory pathogens DNA and RNA 4 panel - Nasopharynx by NAA with probe detection
78922-2	Respiratory pathogens DNA and RNA panel - Nasopharynx by NAA with probe detection
94499-1	Respiratory viral pathogens DNA and RNA panel - Respiratory system specimen Qualitative by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG32757-3	Influenza virus
LG34064-2	Influenza virus A RNA\|PrThr\|Sys:ANYResp

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus chřipky A RNA:Přítomnost nebo práh:Časový bod:Nosohltan:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-AT	German (Austria)	Synonyms: Influenza A Virus RNA /NP PCR
de-DE	German (Germany)	Influenza-Virus A RNA:Nachweis oder Schwellenwert:Zeitpunkt:Nasopharynx:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Ιός γρίπης A RNA:PrThr:Pt:Nph:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: A MICRO Nph Ord PrThr Pt RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός γρίπης Ιός γρίπης A
es-ES	Spanish (Spain)	Virus Influenza A RNA:PrThr:Punto temporal:Nasofaringe:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN del virus de la influenza A:Presencia o umbral:Punto temporal:Nasofaringe:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA	French (Canada)	Virus de l'influenza A ARN:Présence-Seuil:Temps ponctuel:Nasopharynx:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Influenza virus A ARN:Présence/Seuil:Ponctuel:Nasopharynx:Qualitatif:PCR amplification de cible
fr-BE	French (Belgium)	Virus de l'influenza A ARN:PrThr:Temps ponctuel:Nasopharynx:Ordinal:Sonde avec amplification de la cible Synonyms: FLU A virus FLU virus
it-IT	Italian (Italy)	Influenza A, virus RNA:PrThr:Pt:Nph:Ord:Sonda.amp.tar Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Rinofaringe Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A
nl-NL	Dutch (Netherlands)	Influenzavirus A RNA:aanwezigheid:moment:neusholte:ordinaal:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Wirus grypy A RNA:granica wykrywalności:punkt w czasie:nosogardziel:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA wirusa grypy typu A Wirus grypy typ A
ru-RU	Russian (Russian Federation)	Грипп вирус А РНК:PrThr:ТчкВрм:НГл:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Носоглотка Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	İnfluenza virüsü A RNA:MevcEşik:Zmlı:Nfks:Srl:Prob.amf.hdf Synonyms: Mevcut
uk-UA	Ukrainian (Ukraine)	Вірус грипу А РНК:Наявність або Поріг:МоментЧасу:Носоглотка:Порядково:Зонд-детекція. цільова аміпліфікація НК Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Avian influenza; Bird flu; DNA NUCLEIC ACID PROBE; DNA probe; FLUA; FLUAV; FLUV; Fowl plague; ID; Infectious Disease; InfectiousDisease; Influ; Influenza A; Influenza A virus; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Microbiology; NAA+probe; NAAT; NASBA; Nasopharynx; Nucleic acid sequence based analysis; Ordinal; PCR; Point in time; Polymerase chain reaction; PR; Probe amp; Probe with ampification; Probe with target amplification; QBR; QL; Qual; Qualitative; Random; Ribonucleic acid; Screen; SDA; Strand Displacement Amplification; TMA; Transcription mediated amplification
zh-CN	Chinese (China)	流感病毒 A 型 RNA:存在情况或阈值:时间点:鼻咽:序数型:探针法.基因扩增.靶向 Synonyms: A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒 RNA FLUA RNA FLUAV RNA FLUV;Influ;列性感冒病毒;流行性感冒病毒传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 流感病毒甲型 RNA 甲型流感病毒 RNA 经过扩增的脱氧核糖核酸探针鼻咽标本;鼻咽部;鼻咽部标本

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.