76478-7
Acetylcholinesterase panel - Amniotic fluid
Active
18185-9 Gestational age
Part Descriptions
LP19507-0 Gestational age
The age of the conceptus, beginning from the time of fertilization. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last menstruation which is about 2 weeks before ovulation and fertilization.
Source: National Library of Medicine, MeSH 2006
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | This term is preferred over the two separate terms for gestational age in weeks [LOINC: 49051-6] and in days [LOINC: 49052-4] so that only one variable is used. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Observation Required in Panel
Optional
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Gestational age
- Property
- Time
- Time
- Pt
- System
- ^Fetus
- Scale
- Qn
- Method
Additional Names
- Short Name
- GA
Basic Attributes
- Class
- OB.US
- Type
- Clinical
- First Released
- Version 1.0l
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 1105
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 76478-7 | Acetylcholinesterase panel - Amniotic fluid |
| 58735-2 | Alpha-1-Fetoprotein panel - Amniotic fluid |
| 48802-3 | Alpha-1-Fetoprotein panel - Serum or Plasma |
| 75199-0 | Congenital syphilis case investigation and report panel [CDC.CS] |
| 49085-4 | First and Second trimester integrated maternal screen panel |
| 48798-3 | First trimester maternal screen panel - Serum or Plasma |
| 49086-2 | First trimester maternal screen with nuchal translucency panel |
| 49087-0 | Maternal screen clinical predictors panel |
| 96978-2 | Noninvasive prenatal fetal aneuploidy and 22q11.2 deletion panel - Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA |
| 75547-0 | Noninvasive prenatal fetal aneuploidy and microdeletion panel based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific circulating cell free (ccf) DNA |
| 96977-4 | Noninvasive prenatal fetal aneuploidy panel - Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA |
| 100230-2 | Routine prenatal assessment panel |
| 48799-1 | Second trimester penta maternal screen panel - Serum or Plasma |
| 48800-7 | Second trimester quad maternal screen panel - Serum or Plasma |
| 35086-8 | Second trimester triple maternal screen panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG50112-8 | Gestational ageTime^Fetus |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-AR | Spanish (Argentina) | edad gestacional: |
| es-MX | Spanish (Mexico) | Edad gestacional: |
| es-ES | Spanish (Spain) | Edad gestacional: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Raseduse kestus: Synonyms: Juhuslik Kvantitatiivne |
| fr-BE | French (Belgium) | Age gestationnel: |
| fr-FR | French (France) | Âge gestationnel: |
| it-IT | Italian (Italy) | Età gestazionale: Synonyms: Ecografia ostetrica Punto nel tempo (episodio) Tempo (e.g. secondi) |
| nl-NL | Dutch (Netherlands) | zwangerschapsduur: |
| pt-BR | Portuguese (Brazil) | Idade gestacional: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Гестационный возраст: Synonyms: Время (в т.ч. в секундах) Гестационный срок Количественный Точка во времени; |
| tr-TR | Turkish (Turkey) | Doğurma yaşı: Synonyms: Gestasyonel yaş |
| uk-UA | Ukrainian (Ukraine) | Гестаційний вік: Synonyms: Fetal; |
| zh-CN | Chinese (China) | 孕龄: Synonyms: 产科 产科.超声; |
Example Units
| Unit | Source |
|---|---|
| wk | Example UCUM Units |
| week | REGENSTRIEF |
30106-9 Acetylcholinesterase [Presence] in Amniotic fluid
Part Descriptions
LP15315-2 Acetylcholinesterase
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
Source: National Library of Medicine, MeSH 2006
LP15315-2 Acetylcholinesterase
Acetylcholinesterase, an enyzme (EC 3.1.1.7) (AChE) that controls synaptic and neurohumoral cholinergic activity by hydrolyzing the neurotransmitter acetylcholine, is also known as RBC cholinesterase, erythrocyte cholinesterase, or (most formally) acetylcholine acetylhydrolase. The ACHE gene is mapped to chromosome 7q22. AChE is found primarily in the blood on red blood cell membranes, in neuromuscular junctions, and in neural synapses. Two main clinical diagnostic uses are: 1) a second trimester screening test for fetal neural tube defects using amniotic fluid and, 2) in the general population, to detect past exposure to organophosphate insecticides with resultant inhibition of the enzyme using blood.
Source: Regenstrief LOINC, Acetylcholinesterase
Observation Required in Panel
Required
Fully-Specified Name
- Component
- Acetylcholinesterase
- Property
- PrThr
- Time
- Pt
- System
- Amnio fld
- Scale
- Ord
- Method
Additional Names
- Short Name
- AChE Amn Ql
- Display Name
- Acetylcholinesterase Ql (Amn fld)
- Consumer Name Alpha Get Info
- Acetylcholinesterase, Amniotic fluid
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.04
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 7766
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 76478-7 | Acetylcholinesterase panel - Amniotic fluid |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Acetilcolinesterasa: |
| es-AR | Spanish (Argentina) | acetilcolinesterasa: |
| es-ES | Spanish (Spain) | Acetilcolinesterasa: |
| et-EE | Estonian (Estonia) | Atsetüülkoliini esteraas: Synonyms: Amnionivedelik Järgarvuline Juhuslik |
| fr-BE | French (Belgium) | Acétylcholinestérase: |
| fr-FR | French (France) | Acétylcholinestérase: |
| fr-CA | French (Canada) | Acétylcholinestérase: |
| it-IT | Italian (Italy) | Acetilcolinesterasi: Synonyms: Chimica Liquido amniotico Presenza o Soglia Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 아세틸콜린에스테라제: |
| nl-NL | Dutch (Netherlands) | acetylcholinesterase: |
| pt-BR | Portuguese (Brazil) | Acetilcolinesterase: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Ацетилхолинэстераза: Synonyms: Амниотическая жидкость Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | Asetilkolinesteraz: Synonyms: Amniyon mayii Mevcut |
| uk-UA | Ukrainian (Ukraine) | Ацетилхолінестераза: Synonyms: Acetycholinesterase; |
| zh-CN | Chinese (China) | 乙酰胆碱酯酶: Synonyms: AChE; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
76479-5 Acetylcholinesterase [Interpretation] in Amniotic fluid Narrative
Term Description
An interpretation of the acetylcholinesterase (AChE) in amniotic fluid testing result which is used as an aid to diagnose open neural tube defect (NDT) and ventral wall defects. The two most common neural tube defects are spina bifida and anencephaly. When an NTD is suspected based upon maternal serum alpha-fetoprotein (AFP) screening results, or diagnosed via ultrasound, detection of acetylcholinesterase (AChE) in amniotic fluid is a useful diagnostic tool as normal amniotic fluid does not contain AChE, unless from the fetus as a result of an open NTD. The patient's gestational age must be at least 13 weeks (second trimester) for accurate AChE detection. Optimal gestational age is 14 to 18 weeks. If acetylcholinesterase is present genetic consultation and high-resolution ultrasound may be suggested.
Source: Regenstrief LOINC
Part Descriptions
LP15315-2 Acetylcholinesterase
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
Source: National Library of Medicine, MeSH 2006
LP15315-2 Acetylcholinesterase
Acetylcholinesterase, an enyzme (EC 3.1.1.7) (AChE) that controls synaptic and neurohumoral cholinergic activity by hydrolyzing the neurotransmitter acetylcholine, is also known as RBC cholinesterase, erythrocyte cholinesterase, or (most formally) acetylcholine acetylhydrolase. The ACHE gene is mapped to chromosome 7q22. AChE is found primarily in the blood on red blood cell membranes, in neuromuscular junctions, and in neural synapses. Two main clinical diagnostic uses are: 1) a second trimester screening test for fetal neural tube defects using amniotic fluid and, 2) in the general population, to detect past exposure to organophosphate insecticides with resultant inhibition of the enzyme using blood.
Source: Regenstrief LOINC, Acetylcholinesterase
Observation Required in Panel
Required
Fully-Specified Name
- Component
- Acetylcholinesterase
- Property
- Imp
- Time
- Pt
- System
- Amnio fld
- Scale
- Nar
- Method
Additional Names
- Short Name
- AChE Amn-Imp
- Display Name
- Acetylcholinesterase Nar (Amn fld) [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Acetylcholinesterase test result, Amniotic fluid
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 15145
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 76478-7 | Acetylcholinesterase panel - Amniotic fluid |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Acetilcolinesterasa: |
| es-ES | Spanish (Spain) | Acetilcolinesterasa: |
| fr-FR | French (France) | Acétylcholinestérase: |
| fr-BE | French (Belgium) | Acétylcholinestérase: |
| fr-CA | French (Canada) | Acétylcholinestérase: |
| it-IT | Italian (Italy) | Acetilcolinesterasi: Synonyms: Chimica Impressione/interpretazione di studio Liquido amniotico Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | acetylcholinesterase: |
| ru-RU | Russian (Russian Federation) | Ацетилхолинэстераза: Synonyms: Амниотическая жидкость Впечатление/интерпретация исследования Описательный Точка во времени; |
| tr-TR | Turkish (Turkey) | Asetilkolinesteraz: Synonyms: Amniyon mayii |
| zh-CN | Chinese (China) | 乙酰胆碱酯酶: Synonyms: AChE; |
4576-5 Hemoglobin F/Hemoglobin.total in Blood
Part Descriptions
LP16428-2 Hemoglobin F
Hemoglobin F is used to screen for fetal-to-maternal hemorrrhage. The presence of fetal red cells in the maternal circulation may be identified by use of the acid elution principle first described by Kleihauer, Brown, and Betke, or by several modifications. Very small volumes of red cells commonly escape from the fetal intravascular compartment across the placental barrier into the maternal intervillous space.
Source: Regenstrief Institute
Observation Required in Panel
Reflex with alternatives
Fully-Specified Name
- Component
- Hemoglobin F/Hemoglobin.total
- Property
- MFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- Hgb F MFr Bld
- Display Name
- Hemoglobin F (Bld) [Mass fraction]
- Consumer Name Alpha Get Info
- Hemoglobin F/Total Hgb, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 1597
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 76478-7 | Acetylcholinesterase panel - Amniotic fluid |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Hämoglobin F/Hämoglobin.gesamt: |
| de-AT | German (Austria) | Synonyms: Hämoglobin F |
| es-MX | Spanish (Mexico) | Hemoglobina F / Hemoglobina total: |
| es-AR | Spanish (Argentina) | hemoglobina F/hemoglobina.total: |
| es-ES | Spanish (Spain) | Hemoglobina fetal/Hemoglobina.total: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Hemoglobiin F/hemoglobiin.üld: Synonyms: Juhuslik Kvantitatiivne Veri |
| fr-BE | French (Belgium) | Hémoglobine F/Hémoglobine.totale: Synonyms: Hb Hb.totale HbF |
| fr-FR | French (France) | Hémoglobine F/hémoglobine totale: |
| fr-CA | French (Canada) | Hémoglobine F/Hémoglobine.totale: |
| it-IT | Italian (Italy) | Emoglobina F/Emoglobina.totale: Synonyms: Ematologia (coagulazione) conta differenziale Frazione di massa Punto nel tempo (episodio) Sangue |
| ko-KR | Korean (Korea, Republic Of) | 혈색소 F/총혈색소: |
| nl-NL | Dutch (Netherlands) | hemoglobine F/hemoglobine.totaal: |
| pl-PL | Polish (Poland) | Hemoglobina F/hemoglobina całkowita: Synonyms: Hemoglobina F/Hemoglobina całkowita |
| pt-BR | Portuguese (Brazil) | Hemoglobina F/Hemoglobina.total: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Гемоглобин F/Гемоглобин.общий: Synonyms: Количественный Кровь Массовая доля Точка во времени; |
| tr-TR | Turkish (Turkey) | Hemoglobin F/Hemoglobin.total: |
| uk-UA | Ukrainian (Ukraine) | Гемоглобін F/Гемоглобін.загальний: Synonyms: Blood; |
| zh-CN | Chinese (China) | 血红蛋白 F/血红蛋白.总计: Synonyms: HbF; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |