76621-2
Lysosomal acid lipase panel - Fibroblast
Active
76614-7 Lysosomal acid lipase [Enzymatic activity/mass] in Fibroblast by 4-MU-oleate substrate
Part Descriptions
LP189526-9 Lysosomal acid lipase
Lysosomal acid lipase (LAL) is an enzyme that hydrolyzes cholesterol esters and triglycerides. Decreased levels of LAL leads to two autosomal recessive disorders known as Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD). Complete loss of the enzyme causes WD in infants who present with vomiting, diarrhea, poor weight gain and hepatomegaly subsequently leading to death. Partial loss of LAL causes CESD with variable symptoms ranging from asymptomatic to gastrointestinal symptoms, hepatomegaly, elevated transaminases and dyslipidemia. PMID: 25345094
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Lysosomal acid lipase
- Property
- CCnt
- Time
- Pt
- System
- Fibroblasts
- Scale
- Qn
- Method
- 4-MU-oleate substrate
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.52 (MIN)
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 76621-2 | Lysosomal acid lipase panel - Fibroblast |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG29985-5 | Lysosomal acid lipase| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Lysozomální kyselá lipáza: |
| el-GR | Greek (Greece) | Λιπάση λυσοσωμικού οξέος: Synonyms: 4-ΜU-υπόστρωμα ελαϊκού οξέος CCnt CHEM Pt Qn Ινοβλάστες Λιπάση λυσοσωμικού οξέος |
| es-ES | Spanish (Spain) | Lipasa ácida lisosomal: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Lipasa ácida lisosomal: |
| fr-FR | French (France) | Lipase acide lysosomale: |
| it-IT | Italian (Italy) | Lipasi acida lisosomiale: Synonyms: Chimica Contenuto Catalitico Fibroblasto Punto nel tempo (episodio) Substrato 4-MU oleato |
| nl-NL | Dutch (Netherlands) | lysosomale zure lipase: |
| zh-CN | Chinese (China) | 溶酶体酸性脂肪酶: Synonyms: LAL; |
Example Units
| Unit | Source |
|---|---|
| nmol/h/mg{protein} | Example UCUM Units |
76615-4 Lysosomal acid lipase [Enzymatic activity/mass] in Fibroblast by 4-MU-palmitate substrate
Part Descriptions
LP189526-9 Lysosomal acid lipase
Lysosomal acid lipase (LAL) is an enzyme that hydrolyzes cholesterol esters and triglycerides. Decreased levels of LAL leads to two autosomal recessive disorders known as Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD). Complete loss of the enzyme causes WD in infants who present with vomiting, diarrhea, poor weight gain and hepatomegaly subsequently leading to death. Partial loss of LAL causes CESD with variable symptoms ranging from asymptomatic to gastrointestinal symptoms, hepatomegaly, elevated transaminases and dyslipidemia. PMID: 25345094
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Lysosomal acid lipase
- Property
- CCnt
- Time
- Pt
- System
- Fibroblasts
- Scale
- Qn
- Method
- 4-MU-palmitate substrate
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 17095
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 76621-2 | Lysosomal acid lipase panel - Fibroblast |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG29985-5 | Lysosomal acid lipase| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Lysozomální kyselá lipáza: |
| el-GR | Greek (Greece) | Λιπάση λυσοσωμικού οξέος: Synonyms: 4-MU-παλμιτικό υπόστρωμα CCnt CHEM Pt Qn Ινοβλάστες Λιπάση λυσοσωμικού οξέος |
| es-ES | Spanish (Spain) | Lipasa ácida lisosomal: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Lipasa ácida lisosomal: |
| fr-FR | French (France) | Lipase acide lysosomale: |
| it-IT | Italian (Italy) | Lipasi acida lisosomiale: Synonyms: Chimica Contenuto Catalitico Fibroblasto Punto nel tempo (episodio) Substrato 4-MU palmitato |
| nl-NL | Dutch (Netherlands) | lysosomale zure lipase: |
| zh-CN | Chinese (China) | 溶酶体酸性脂肪酶: Synonyms: LAL; |
Example Units
| Unit | Source |
|---|---|
| nmol/h/mg{protein} | Example UCUM Units |
76622-0 Lysosomal acid lipase [Interpretation] in Fibroblast Narrative
Part Descriptions
LP189526-9 Lysosomal acid lipase
Lysosomal acid lipase (LAL) is an enzyme that hydrolyzes cholesterol esters and triglycerides. Decreased levels of LAL leads to two autosomal recessive disorders known as Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD). Complete loss of the enzyme causes WD in infants who present with vomiting, diarrhea, poor weight gain and hepatomegaly subsequently leading to death. Partial loss of LAL causes CESD with variable symptoms ranging from asymptomatic to gastrointestinal symptoms, hepatomegaly, elevated transaminases and dyslipidemia. PMID: 25345094
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Lysosomal acid lipase
- Property
- Imp
- Time
- Pt
- System
- Fibroblasts
- Scale
- Nar
- Method
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.52 (MIN)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 76621-2 | Lysosomal acid lipase panel - Fibroblast |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Lysozomální kyselá lipáza: |
| el-GR | Greek (Greece) | Λιπάση λυσοσωμικού οξέος: Synonyms: CHEM Imp Nar Pt Ινοβλάστες Λιπάση λυσοσωμικού οξέος |
| es-ES | Spanish (Spain) | Lipasa ácida lisosomal: |
| es-MX | Spanish (Mexico) | Lipasa ácida lisosomal: |
| fr-FR | French (France) | Lipase acide lysosomale: |
| it-IT | Italian (Italy) | Lipasi acida lisosomiale: Synonyms: Chimica Fibroblasto Impressione/interpretazione di studio Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | lysosomale zure lipase: |
| tr-TR | Turkish (Turkey) | Lizozomal asit lipaz: |
| zh-CN | Chinese (China) | 溶酶体酸性脂肪酶: Synonyms: LAL; |