Version 2.78

Part Description

LP15448-1   Bilirubin
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin). Source: Regenstrief LOINC

Reference Information

Type Source Reference
Mapping Guidance LOINC This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished.
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Bilirubin

Fully-Specified Name

Component
Bilirubin
Property
SCnc
Time
Pt
System
Ser/Plas/Bld
Scale
Qn
Method

Additional Names

Short Name
Bilirub SerPlBld-sCnc
Display Name
Bilirubin (S/P/Bld) [Moles/Vol]
Consumer Name Alpha Get Info
Bilirubin, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.68
Change Reason
Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG2811-0 Bilirubin|SCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bilirubin:Stoffmengenkonzentration:Zeitpunkt:Serum, Plasma oder Blut:Quantitativ:
es-ES Spanish (Spain) Bilirrubina:Concentración de sustancia:Punto temporal:Suero, Plasma o Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Bilirrubina:Concentración de sustancias:Punto temporal:Suero, plasma o sangre:Cuantitativo:
et-EE Estonian (Estonia) Bilirubiin:SCnc:Pt:S/P/B:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma Seerum või plasma või veri Veri
fr-CA French (Canada) Bilirubine:Concentration de substance:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-FR French (France) Bilirubine:Moles/Volume:Ponctuel:Sérum/Plasma/Sang:Numérique:
fr-BE French (Belgium) Bilirubine:Concentration de substance:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
it-IT Italian (Italy) Bilirubina:SCnc:Pt:Siero/Plasma/Sangue:Qn:
Synonyms: Chimica Concentrazione di Sostanza Plasma Plasma o Sangue Punto nel tempo (episodio) Sangue Siero Siero o Plasma Siero,Plasma o Sangue
nl-NL Dutch (Netherlands) bilirubine:mol/volume:moment:serum of plasma of bloed:kwantitatief:
pl-PL Polish (Poland) Bilirubina:stężenie molowe:punkt w czasie:surowica, osocze lub krew:ilościowy:
ru-RU Russian (Russian Federation) Билирубин:МолКонц:ТчкВрм:Сыв/Плаз/Кр:Колич:
Synonyms: Количественный Кровь Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Сыворотка, Плазма или Кровь Точка во времени;Момент
tr-TR Turkish (Turkey) Bilirubin:SubKons:Zmlı:Ser/Plaz/Kan:Kant:
zh-CN Chinese (China) 胆红素:物质的量浓度:时间点:血清/血浆/全血:定量型:
Synonyms: TBIL;总胆红素;胆红质 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血;血液 血浆或全血;血浆/血液;血浆或血液 血清、血浆或全血;血清、血浆或血液;血清/血浆/血液 血清或血浆

Example Units

Unit Source
umol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77137-8